0000000000117186

AUTHOR

Vito R. Cicinnati

showing 4 related works from this author

Hepatic Hilar and Sectorial Vascular and Biliary Anatomy in Right Graft Adult Live Liver Donor Transplantation

2008

Abstract Introduction The aim of this study was to analyze vascular and biliary variants at the hilar and sectorial level in right graft adult living donor liver transplantation. Methods From January 2003 to June 2007, 139 consecutive live liver donors underwent three-dimensional computed tomography (3-D CT) reconstructions and virtual 3-D liver partitioning. We evaluated the portal (PV), arterial (HA), and biliary (BD) anatomy. Results The hilar and sectorial biliary/vascular anatomy was predominantly normal (70%–85% and 67%–78%, respectively). BD and HA showed an equal incidence (30%) of hilar anomalies. BD and PV had a nearly identical incidence of sectorial abnormalities (64.7% and 66.2…

Adultmedicine.medical_specialtyCholecystographymedicine.medical_treatmentHilum (biology)Hepatic VeinsLiver transplantationliverHepatic ArteryImage Processing Computer-AssistedLiving DonorsmedicineHumansPorta hepatisTransplantationmedicine.diagnostic_testbusiness.industryGallbladderCholecystographyLiver TransplantationSurgeryTransplantationmedicine.anatomical_structureBiliary tractCirculatory systemSurgeryHepatectomyTomography X-Ray ComputedNuclear medicinebusinessTransplantation Proceedings
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A New Systematic Classification of Peripheral Anatomy of the Right Hepatic Duct: Experience From Adult Live Liver Donor Transplantation

2008

Abstract Objective The peripheral intrahepatic biliary anatomy, especially at the sectorial level on the right side, has not been adequately described. The purpose of our study was to systematically describe this complex anatomy in clinically applicable fashion. Patients and Methods We analyzed three-dimensional computed tomography (CT) imaging reconstructions of 139 potential living liver donors evaluated at our institution between January 2003 and June 2007. Results Eighty-nine (64%) donors had a normal right bile duct sectorial anatomy. In the other 50/139 (36%) cases, we observed abnormal sectorial branching patterns, with 45/50 abnormalities as trifurcations, whereas the remaining ones…

Adultmedicine.medical_treatmentHepatic Duct CommonLiver transplantationAnastomosisFunctional LateralityCholangiographyImage Processing Computer-AssistedLiving DonorsmedicineHumansSurvivorsTransplantationmedicine.diagnostic_testBile ductbusiness.industryGallbladderAnastomosis SurgicalGallbladderAnatomyLobeCholecystographyLiver TransplantationSurvival RateTransplantationmedicine.anatomical_structureSurgeryBile DuctsHepatectomyTomography X-Ray ComputedbusinessCholangiographyTransplantation Proceedings
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Liver transplantation with grafts from septuagenarians.

2008

Abstract Background The purpose of this study was to evaluate our experience with orthotopic liver transplantation (OLT) using grafts from septuagenarians. Patients and Methods Seventeen adult patients underwent transplantation with grafts from donors 70 years of age or older during an 8-year period. Results The median donor age was 73 years (range, 70–83). Eleven (64.7%) donors had experienced at least 1 hypotensive period and received vasoactive drugs. Median cold and warm ischemia times were 7.25 hours and 35 minutes, respectively. Two recipients underwent retransplantation because of dysfunction or primary nonfunction. Morbidity rate was 47% and hospital mortality rate was 23.5%. After …

MaleReoperationmedicine.medical_specialtymedicine.medical_treatmentHospital mortalityLiver transplantationVasoactiveCause of DeathmedicineHumansHospital MortalitySurvival rateCause of deathAgedRetrospective StudiesAged 80 and overTransplantationbusiness.industryMortality rateRetrospective cohort studyTissue DonorsSurgeryLiver TransplantationTransplantationSurvival RateSurgeryFemalebusinessLiver FailureTransplantation proceedings
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Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: identification of an H2-Kd-restricted CTL epitope

2000

Enhanced green fluorescent protein (EGFP) is a novel marker gene product, which is readily detectable using techniques of fluorescence microscopy, flow cytometry, or macroscopic imaging. In the present studies, we have examined the immunogenicity of EGFP in murine models. A stable transfectant of the transplantable CMS4 sarcoma of BALB/c origin expressing EGFP, CMS4-EGFP-Zeo, was generated. Splenocytes harvested from mice immunized with a recombinant adenovirus expressing EGFP (Ad-EGFP) were restimulated in vitro with CMS4-EGFP-Zeo. Effector lymphocytes displayed strong cytotoxicity against CMS4-EGFP-Zeo, but not against mock-transfected CMS4-Zeo tumor cells. A number of candidate H2-Kd-bin…

Green Fluorescent ProteinsBiologyCancer VaccinesEpitopeBALB/cFlow cytometryGreen fluorescent proteinMiceAntigenAntigens NeoplasmGeneticsmedicineAnimalsMolecular BiologyMice Inbred BALB Cmedicine.diagnostic_testImmunogenicityfungiH-2 Antigensbiology.organism_classificationMolecular biologyTumor antigenIn vitroLuminescent ProteinsModels AnimalMolecular MedicineT-Lymphocytes CytotoxicGene Therapy
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