0000000000117238

AUTHOR

E Topinkova

0000-0002-6786-4116

showing 6 related works from this author

Using the Multidimensional Prognostic Index to Predict Clinical Outcomes of Hospitalized Older Persons: A Prospective, Multicenter, International Stu…

2018

Abstract Background Multidimensional Prognostic Index (MPI) is useful as a prognostic tool in hospitalized older patients, but our knowledge is derived from retrospective studies. We therefore aimed to evaluate in a multicenter, longitudinal, cohort study whether the MPI at hospital admission is useful to identify groups with different mortality risk and whether MPI at discharge may predict institutionalization, rehospitalization, and use of home care services during 12 months. Methods This longitudinal study, carried out between February 2015 and August 2017, included nine public hospitals in Europe and Australia. A standardized comprehensive geriatric assessment including information on f…

MaleAgingmedicine.medical_specialtyLongitudinal studyIndex (economics)InstitutionalisationPrognosi030204 cardiovascular system & hematologyRisk Assessment03 medical and health sciencesHospital0302 clinical medicinePredictive Value of TestsMultidimensional Prognostic IndexmedicineRisk of mortalityHumansLongitudinal StudiesProspective Studies030212 general & internal medicineGeriatric AssessmentAgedAged 80 and overbusiness.industryAustraliaRetrospective cohort studyOdds ratioPrognosisEuropeHospitalizationROC CurveThe Journal of Gerontology: Medical SciencesEmergency medicineCohortFemaleGeriatrics and GerontologybusinessCohort studyCohort study
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Enteral tube feeding and mortality in hospitalized older patients: A multicenter longitudinal study

2020

Background & aims: The literature regarding enteral nutrition and mortality in older frail people is limited and still conflicting. Moreover, the potential role of comprehensive geriatric assessment is poorly explored. We therefore aimed to investigate whether the Multidimensional Prognostic Index (MPI), an established tool that assesses measures of frailty and predicts mortality, may help physicians in identifying patients in whom ETF (enteral tube feeding) is effective in terms of reduced mortality. Methods: Observational, longitudinal, multicenter study with one year of follow-up. Data regarding ETF were recorded through medical records. A standardized comprehensive geriatric assessm…

Male0301 basic medicinemedicine.medical_specialtyLongitudinal studyPrognosis.030209 endocrinology & metabolismCritical Care and Intensive Care MedicineHospital03 medical and health sciences0302 clinical medicineMultidimensional prognostic indexOdds RatiomedicineRisk of mortalityHumansLongitudinal StudiesMortalityAgedEnteral Tube FeedingAged 80 and overInpatients030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryMedical recordAustraliaOdds ratioConfidence intervalEuropeParenteral nutritionEmergency medicinePropensity score matchingFemaleEnteral nutritionbusinessClinical Nutrition
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Older women are frailer, but less often die then men: a prospective study of older hospitalized people

2019

Abstract Objectives The association between frailty, mortality and sex is complex, but a limited literature is available on this topic, particularly for older hospitalized patients. Therefore, the objective of our study was to prospectively evaluate sex differences in frailty, assessed by the Multidimensional Prognostic Index (MPI) and mortality, institutionalization, and re-hospitalization in an international cohort of older people admitted to hospital. Study design We used data from nine public hospitals in Europe and Australia, to evaluate sex differences in mortality, frailty and the risk of institutionalization and re-hospitalization, during one year of follow-up. Main outcome measures…

MaleGerontologyMultivariate analysisPrognosiLower riskArticleGeneral Biochemistry Genetics and Molecular BiologyHospital03 medical and health sciences0302 clinical medicineMultidimensional Prognostic IndexHumansMedicineLongitudinal StudiesProspective Studies030212 general & internal medicineProspective cohort studyGeriatric AssessmentAgedAged 80 and overSex Characteristics030219 obstetrics & reproductive medicineFrailtybusiness.industryMortality rateAustraliaObstetrics and GynecologyOdds ratioPrognosisHospitalsPatient DischargeConfidence intervalEuropeHospitalizationSurvival RateCohortSexFemaleCohort studybusinessCohort studyMaturitas
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The role of prognostic stratification on prescription of anticoagulants in older patients with atrial fibrillation : a multicenter, observational, pr…

2022

Background: Literature suggests that different risks of mortality could influence physicians in prescribing or not anticoagulants in older patients with atrial fibrillation (AF). The Multidimensional Prognostic Index (MPI) can be considered a tool for the detection of multidimensional frailty. The aim of this cross-sectional study was to evaluate whether prescription patterns of oral anticoagulants exist, based on MPI values. Methods: Older hospitalised patients (age >= 65 years) with non-valvular AF were included across 24 European centres. MPI was calculated using validated and standardised tools derived from a comprehensive geriatric assessment. Other functional and clinical information …

EUROSAF; anticoagulants; comprehensive geriatric assessment; frailty; multidimensional prognostic index; older peopleanticoagulantsAdministration OralfrailtyVALIDATIONolder peopleRisk FactorsAtrial FibrillationEUROSAFHumansProspective StudiesELDERLY-PATIENTSINDEXAgedAged 80 and overMORTALITYGeneral MedicineADULTScomprehensive geriatric assessmentPrognosismultidimensional prognostic indexCross-Sectional StudiesPrescriptions3121 General medicine internal medicine and other clinical medicineFemaleEUROSAF anticoagulants comprehensive geriatric assessment frailty multidimensional prognostic index older peopleSTROKE
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Can the Multidimensional Prognostic Index Improve the Identification of Older Hospitalized Patients with COVID-19 Likely to Benefit from Mechanical V…

2022

Objective: Data on prognostic tools for indicating mechanical ventilation in older people with COVID-19 are still limited. The aim of this research was to evaluate if the Multidimensional Prognostic Index (MPI), based on the Comprehensive Geriatric Assessment (CGA), may help physicians in identifying older hospitalized patients affected by COVID-19 who might benefit from mechanical ventilation.Design: Longitudinal, multicenter study.Settings and Participants: 502 older people hospitalized for COVID-19 in 10 European hospitals.Methods: MPI was calculated using 8 different domains typical of the CGA. A propensity score, Cox's regression analysis was used for assessing the impact of mechanical…

Aged 80 and overHealth PolicyCOVID-19HumansProspective StudiesGeneral MedicineCOVID-19 Comprehensive Geriatric Assessment Multidimensional Prognostic Index mechanical ventilation mortalitynoninvasive ventilation prognosisGeriatrics and GerontologyPrognosisGeriatric AssessmentRespiration ArtificialGeneral NursingAgedJournal of the American Medical Directors Association
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Association of Antidementia Drugs and Mortality in Community-Dwelling Frail Older Patients With Dementia: The Role of Mortality Risk Assessment

2018

Objective: To evaluate whether treatment with antidementia drugs is associated with reduced mortality in older patients with different mortality risk at baseline. Design: Retrospective. Setting: Community-dwelling. Participants: A total of 6818 older people who underwent a Standardized Multidimensional Assessment Schedule for Adults and Aged Persons (SVaMA) evaluation to determine accessibility to homecare services or nursing home admission from 2005 to 2013 in the Padova Health District, Italy were included. Measurements: Mortality risk at baseline was calculated by the Multidimensional Prognostic Index (MPI), based on information collected with the SVaMA. Participants were categorized to …

MaleGerontologymedicine.medical_specialtyFrail ElderlyMultidimensional assessmentantidementia drugLower riskComprehensive geriatric assessmentRisk AssessmentArticle03 medical and health sciences0302 clinical medicineOlder patientsSDG 3 - Good Health and Well-beingRisk Factorsantidementia drugs; comprehensive geriatric assessment; Dementia; frailty; mortality; multidimensional prognostic index (MPI); Nursing (all)2901 Nursing (miscellaneous); Health Policy; Geriatrics and GerontologyInternal medicinemedicineHumansDementia030212 general & internal medicineMultidimensional prognostic index (MPI)MortalityGeriatric AssessmentNursing (all)2901 Nursing (miscellaneous)General NursingAgedRetrospective StudiesAged 80 and overFrailtybusiness.industryHealth PolicyHazard ratioGeneral Medicinemedicine.diseaseSurvival AnalysisConfidence intervalAntidementia drugs; Comprehensive geriatric assessment; Dementia; Frailty; Mortality; Multidimensional prognostic index (MPI); Nursing (all)2901 Nursing (miscellaneous); Health PolicyAntidementia drugsFemaleDementiaIndependent LivingGeriatrics and GerontologyNursing homesbusinessRisk assessment030217 neurology & neurosurgery
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