Downregulated expression of Cdc25A gene in MCF-7 breast cancer cell

BRCA1 and BRCA2 variants of uncertain clinical significance and their implications for genetic counseling

Molecular screening of the BRCA1/2 genes and clinical significance of unknown sequence variants in families with hereditary breast/ovarian cancer

BRCA1 and BRCA2 germline mutations in sicilian breast and/or ovarian cancer families and their association with familial profiles

EGF Induces STAT3-Dependent VEGF Expression in HT-29 colon cancer cells

Analysis of Germline Gene Copy Number Variants of Patients with Sporadic Pancreatic Adenocarcinoma Reveals Specific Variations

<b><i>Objectives:</i></b> The rapid fatality of pancreatic cancer is, in large part, the result of diagnosis at an advanced stage in the majority of patients. Identification of individuals at risk of developing pancreatic adenocarcinoma would be useful to improve the prognosis of this disease. There is presently no biological or genetic indicator allowing the detection of patients at risk. Our main goal was to identify copy number variants (CNVs) common to all patients with sporadic pancreatic cancer. <b><i>Methods:</i></b> We analyzed gene CNVs in leukocyte DNA from 31 patients with sporadic pancreatic adenocarcinoma and from 93 matched contr…

Synthesis and Characterization of a cordierite monolith supported Pt(1%)/Ce0.6Zr0.4O2 catalyst for TWC applications

VUS variants in BRCA genes of hereditary breast/ovarian cancer