0000000000121547

AUTHOR

A. Stepniak

showing 4 related works from this author

Multirotations-CT und ARDS

2001

Purpose Aim of the study was to investigate alveolar inspiration and expiration using multiscan CT. Results of a visual assessment using a scoring system were compared with density ranges known to represent alveolar ventilation best. Method Pigs were examined before and after lavage-induced ARDS. All animals were examined using dynamic multiscan CT. The visual assessment was done by a scoring system proposed by Gattinoni. The results were compared with planimetric determination of defined density ranges. Results In the healthy lung, the visual analysis showed higher scores at lower airway pressures with a marked gradient, whereas at higher pressures neither opacities nor gradients were obse…

ARDSScoring systemLungAirway pressuresbusiness.industryAcute respiratory distressrespiratory systemmedicine.diseaserespiratory tract diseasesLung densitymedicine.anatomical_structureMedicineRadiology Nuclear Medicine and imagingExpirationTomographybusinessNuclear medicineDer Radiologe
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A novel technique to follow fast PaO2 variations during experimental CPR

2003

An ultrafast responding fluorescent-quenching PO2 probe allows time-resolved, in vivo measurement of PO2. This study describes several validation experiments of this new device in vitro, and reports its first use during cardiopulmonary resuscitation in an animal model of cardiac arrest.The influence of CO2, temperature and motion artefacts on the signal response of the PO2 probe was analysed in vitro by systematic variation of these values. Thereafter, with approval of the Review Board for the care and use of animals, CPR was performed in four pigs. The PaO2 course was recorded continuously at time resolution of80 ms in the abdominal aorta using an uncoated fluorescence-quenching probe (Fox…

Novel techniquemedicine.medical_specialtySwineDefibrillationPartial Pressuremedicine.medical_treatmentEmergency NursingSignalAnimal modelIn vivoIntensive caremedicineAnimalsFiber Optic TechnologyCardiopulmonary resuscitationFluorescent Dyesbusiness.industryTemperatureTime resolutionEquipment DesignCarbon DioxideCardiopulmonary ResuscitationHeart ArrestSurgeryOxygenDisease Models AnimalEmergency MedicineArtifactsCardiology and Cardiovascular MedicinebusinessBiomedical engineering
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Functional Evaluation of Emphysema Using Diffusion-Weighted 3Helium-Magnetic Resonance Imaging, High-Resolution Computed Tomography, and Lung Functio…

2004

Purpose: To assess the emphysematous enlargement of distal air-spaces and concomitant large and small airway disease using diffusion-weighted 3 Helium-magnetic resonance imaging (MRI), high-resolution computed tomography (HRCT), and lung function tests (LFT). Methods: Seven patients were examined after single lung transplantation (LTx) and 1 before double LTx for various forms of emphysema. Five patients after double LTx served as controls. Patients were assessed by 3 Helium-MRI (apparent diffusion coefficient [ADC]), HRCT (mean lung density [MLD], emphysema index [El]), and LFT. Results: Transplanted lungs: mean ADC = 0.17 cm 2 /s, MLD = -848 H, El = 22%. Emphysematous lungs: mean ADC = 0.…

Malemedicine.medical_specialtyHigh-resolution computed tomographyHeliumPulmonary function testingIsotopesmedicineHumansEffective diffusion coefficientRadiology Nuclear Medicine and imagingFunctional evaluationmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingGeneral MedicineMiddle Agedrespiratory systemSingle Lung TransplantationMagnetic Resonance ImagingRespiratory Function Testsrespiratory tract diseasesLung densityPulmonary EmphysemaConcomitantFemaleRadiologyTomography X-Ray ComputedbusinessNuclear medicineLung TransplantationInvestigative Radiology
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Quantifizierung von Atelektasen bei kontrollierter Beatmung: Spiral-CT versus dynamische Einzelschicht-CT

2004

Ziel: Dynamische CT-Untersuchungen (dCT) erlauben die Darstellung und Quantifizierung ventilierter Lungenflache und Atelektasenbildung wahrend kontinuierlicher Beatmung. Diese Studie ­vergleicht eine quantitative Auswertung einer infrakarinalen dCT-Einzelschicht mit der einer Spiral-CT der gesamten Lunge, um zu untersuchen, ob eine dynamisch gemessene Einzelschicht bezuglich der intrapulmonalen Atelektasenverteilung reprasentativ fur die Gesamtlunge ist. Material und Methoden: An 8 gesunden Schweinen erfolgte eine dCT (Schichtdicke 1 mm, zeitliches Inkrement 100 ms) wahrend kontinuierlicher Beatmung, gefolgt von einer Spiral-CT der gesamten Lunge (Schichtdicke 2 mm; Pitch 1,5; Inkrement 2 m…

Mechanical ventilationPathologymedicine.medical_specialtyLungbusiness.industrySlice thicknessSoftware toolmedicine.medical_treatmentAtelectasismedicine.diseasemedicine.anatomical_structureLung segmentationmedicineHigh temporal resolutionRadiology Nuclear Medicine and imagingDynamic ctNuclear medicinebusinessRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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