0000000000122988

AUTHOR

Antoine Bril

showing 2 related works from this author

Late neointimal tissue growth behind the stent after intravascular gamma-radiation.

2003

To determine the nature of the changes of the vascular wall after intravascular brachytherapy in stented arteries leading to incomplete stent apposition.Stents were implanted in the infrarenal aortas of rabbits, and gamma-intravascular brachytherapy (18 Gy) or a sham radiation procedure was immediately implemented. The arteries were harvested at 6 months for histologic analyses.The external elastic lamina area, as well as the vascular wall area behind the stent, were significantly greater in irradiated vs. control arteries (8.94 +/- 0.68 mm2 vs. 6.87 +/- 0.40 mm2 [p0.001] and 1.56 +/- 0.13 mm2 vs. 0.72 +/- 0.07 mm2 [p0.001], respectively). The ratio of the intimal area behind the stent rela…

MaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmentBrachytherapyBrachytherapyConstriction PathologicConstrictionRestenosismedicine.arterymedicineAnimalsRadiology Nuclear Medicine and imagingAorta AbdominalAortaRadiationγ radiationbusiness.industryStentIncomplete stent appositionmedicine.diseaseOncologyIntravascular brachytherapyGamma RaysStentsRadiologyRabbitsbusinessTunica IntimaInternational journal of radiation oncology, biology, physics
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Interpretation of epicardial mapping by means of computer simulations: Applications to calcium, lidocaine and to BRL 34915

1992

The aim of this work was to compare experimental investigations on effects of lidocaine, calcium and, BRL 34915 on reentries to simulated data obtained by use of a model of propagation based on the Huygens' construction method already described in previous works. Calcium and lidocaine effects are investigated on anisotropic conduction conditions. In both cases, reduction in conduction velocities are observed. In lidocaine case, a refractory area is located along the longitudinal axis. In agreement with experimental electrical mapping, the simulations show that the stabilization of reentrant excitation is mainly due to the existence of this refractory area around which the reentrant circuit …

CromakalimMaterials scienceLidocaineRefractory periodchemistry.chemical_elementCalciumGeneral Biochemistry Genetics and Molecular BiologyConstrictionDogsHeart Conduction SystemmedicineAnimalsTachycardia Atrioventricular Nodal ReentryBenzopyransComputer SimulationPyrrolesAntihypertensive AgentsGeneral Environmental ScienceApplied MathematicsModels CardiovascularLidocaineGeneral MedicineReentryMechanicsThermal conductionElectrophysiologyPhilosophyElectrophysiologyReentrancychemistryAnisotropyCalciumGeneral Agricultural and Biological Sciencesmedicine.drugActa Biotheoretica
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