0000000000124413

AUTHOR

Nicholas A. Ratamess

showing 12 related works from this author

The effects of amino acid supplementation on hormonal responses to resistance training overreaching.

2005

The purpose of this investigation was to examine the effects of amino acid supplementation on muscular performance and resting hormone concentrations during resistance training overreaching. Seventeen resistance-trained men were randomly assigned to either an amino acid (AA) or a placebo (P) group and underwent 4 weeks of total-body resistance training designed to induce a state of overreaching. The protocol consisted of two 2-week phases (phase 1, 3 sets of 8 exercises performed for 8-12 repetitions; phase 2, 5 sets of 5 exercises performed for 3-5 repetitions). Muscle strength and resting blood samples were determined before (T1) and at the end of each training week (T2-T5). One-repetitio…

AdultMalemedicine.medical_specialtyGlobulinAnabolismHydrocortisoneEndocrinology Diabetes and MetabolismBench presschemistry.chemical_compoundHemoglobinsEndocrinologyDouble-Blind MethodInternal medicineSex Hormone-Binding GlobulinmedicineHumansTestosteroneAmino AcidsInsulin-Like Growth Factor ICreatine KinaseTestosteroneExercise TolerancebiologyHuman Growth HormoneOverreachingHormonesPeptide FragmentsUric AcidEndocrinologychemistryDietary Supplementsbiology.proteinUric acidCreatine kinaseHormoneMetabolism: clinical and experimental
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Changes in Exercise Performance and Hormonal Concentrations Over a Big Ten Soccer Season in Starters and Nonstarters

2004

As a consequence of the physiological demands experienced during a competitive soccer season, the antagonistic relationship between anabolic and catabolic processes can affect performance. Twenty-five male collegiate soccer players were studied throughout a season (11 weeks) to investigate the effects of long-term training and competition. Subjects were grouped as starters (S; n = 11) and nonstarters (NS; n = 14). Measures of physical performance, body composition, and hormonal concentrations (testosterone [T] and cortisol [C]) were assessed preseason (T1) and 5 times throughout the season (T2-T6). Starters and NS participated in 83.06% and 16.95% of total game time, respectively. Nonstarte…

medicine.medical_specialtyKnee extensorsAnabolismOvertrainingbusiness.industryPhysical Therapy Sports Therapy and RehabilitationGeneral Medicinemedicine.diseaseVertical jumpAnimal scienceSprintExercise performancemedicinePhysical therapyOrthopedics and Sports Medicinebusinesshuman activitiesTestosteroneHormoneThe Journal of Strength and Conditioning Research
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The effect of heavy resistance exercise on the circadian rhythm of salivary testosterone in men.

2001

Circadian rhythms of serum testosterone concentrations in men have been shown, in general, to be highest in the morning and lowest in the evening. Thus, the purpose of this investigation was to determine the effects of acute resistance exercise upon the waking circadian rhythm of salivary testosterone over 2 days (with or without resistance exercise). The subjects included ten resistance-trained men (with at least 1 year of lifting experience) with the following characteristics [mean (SD)]: age 21.6 (1.1) years; height 177.8 (9.5) cm; body mass 80.5 (11.5) kg; percent body fat 7.9 (1.7)%. A matched, randomized, crossover study design was used such that each subject was tested under both the…

AdultMalemedicine.medical_specialtyEveningWeight LiftingPhysiologyStrength trainingPhysical exercisePhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineTestosteroneCircadian rhythmExercise physiologySalivaExerciseMorningChronobiologyCross-Over Studiesbusiness.industryPublic Health Environmental and Occupational HealthGeneral MedicineCrossover studyCircadian RhythmEndocrinologybusinessEuropean journal of applied physiology
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Elevated endogenous testosterone concentrations potentiate muscle androgen receptor responses to resistance exercise.

2009

The purpose of this study was to determine the influence of endogenous circulating testosterone (T) on muscle androgen receptor (AR) responses to acute resistance exercise (RE). Six healthy men (26+/-4 years; 176+/-5 cm; 75.8+/-11.4 kg) performed a knee extension exercise protocol on two occasions separated by 1-3 weeks. Rest preceded one trial (i.e., control [CON] trial) and a high-volume upper-body RE protocol designed to increase circulating T preceded the other trial (i.e., high T [HT] trial). Serial blood samples were obtained throughout each trial to determine circulating T concentrations. Biopsies of the vastus lateralis were obtained pre-RE (REST), 10-min post-RE (+10), and 180-min …

AdultMalemedicine.medical_specialtyTime FactorsAnabolismmedicine.drug_classEndocrinology Diabetes and MetabolismRestClinical BiochemistryBiologyBiochemistryQuadriceps MuscleYoung AdultEndocrinologyInternal medicinemedicineHumansTestosteroneExercise physiologyReceptorMuscle SkeletalMolecular BiologyExerciseTestosteroneCell BiologyAndrogenAndrogen receptorEndocrinologyReceptors AndrogenArea Under CurveMolecular Medicinemedicine.symptomHormoneMuscle contractionThe Journal of steroid biochemistry and molecular biology
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The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching

2003

To determine the effects of creatine supplementation during short-term resistance training overreaching on performance, body composition, and resting hormone concentrations, 17 men were randomly assigned to supplement with 0.3 g/kg per day of creatine monohydrate (CrM: n=9) or placebo (P: n=8) while performing resistance exercise (5 days/week for 4 weeks) followed by a 2-week taper phase. Maximal squat and bench press and explosive power in the bench press were reduced during the initial weeks of training in P but not CrM. Explosive power in the bench press, body mass, and lean body mass (LBM) in the legs were augmented to a greater extent in CrM ( P<or=0.05) by the end of the 6-week period…

AdultMalemedicine.medical_specialtyPhysiologyStrength trainingAdministration OralBlood PressureCreatineBench presschemistry.chemical_compoundHeart RatePhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineMuscle SkeletalPhysical Education and Trainingbusiness.industryOvertrainingFree androgen indexPublic Health Environmental and Occupational HealthGeneral MedicineCreatineOverreachingmedicine.diseaseAdaptation PhysiologicalHormonesEndocrinologychemistryDietary SupplementsBody CompositionPhysical EnduranceLean body massCreatine MonohydratebusinessPsychomotor PerformanceMuscle ContractionEuropean Journal of Applied Physiology
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Recovery from a national collegiate athletic association division I football game: muscle damage and hormonal status.

2008

The purpose of this study was to examine markers of skeletal muscle tissue damage and circulating anabolic and catabolic hormones to gain insight into the recovery process from Friday until Monday, when a new practice week begins. Twenty-eight National Collegiate Athletic Association Division I football players gave consent to participate in the investigation in the ninth game of the season. Sixteen players started the game and played the entire game (PL), and 12 others did not play and were on the bench during the game (DNP). Each player had fasted blood samples obtained at the same time of day between 1000 and 1200 hours the day before the game (Friday; T1), 18-20 hours after the game (Su…

Malemedicine.medical_specialtyTime FactorsAnabolismHydrocortisoneUniversitiesFootballAmerican footballPhysiologyPhysical Therapy Sports Therapy and RehabilitationEndocrine SystemFootballAthletic PerformanceRisk AssessmentCohort StudiesYoung AdultmedicineHumansOrthopedics and Sports MedicineTestosteroneMuscle SkeletalCreatine KinaseTestosteronebiologyL-Lactate DehydrogenaseCatabolismbusiness.industryMyoglobinGeneral MedicineRecovery of Functionmedicine.diseaseSoft tissue injuryMuscle FatiguePhysical therapybiology.proteinCreatine kinasebusinesshuman activitiesBlood Chemical AnalysisHormoneJournal of strength and conditioning research
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On “The Basics of Training for Muscle Size and Strength”

2020

medicine.medical_specialtyText miningMuscle sizePhysical medicine and rehabilitationbusiness.industrySports scienceMEDLINEmedicineTraining (meteorology)Physical Therapy Sports Therapy and RehabilitationOrthopedics and Sports MedicinebusinessPsychologyMedicine &amp; Science in Sports &amp; Exercise
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Differential effects of exhaustive cycle ergometry on concentric and eccentric torque production.

2001

The purpose of this study was to investigate the potential differences in peak isokinetic concentric end eccentric torque following low- and high-intensity cycle exercise fatigue protocols. Ten healthy, recreationally-active men were tested in a balanced, randomized testing sequence for peak eccentric and concentric isokinetic torque (60 degrees/sec) immediately before and after three experimental conditions each separated by 48 hours: 1) a bout of high intensity cycling consisting of a maximal 90-second sprint; 2) a bout of low-intensity cycling at 60 rpm equated for total work with the high-intensity protocol: and 3) no exercise (control bout). Blood was drawn from an antecubital vein and…

AdultMalemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationConcentricInternal medicinemedicineEccentricTorqueHumansOrthopedics and Sports MedicineKneeLactic AcidExercise physiologyMuscle SkeletalExerciseCross-Over StudiesPhysical Education and TrainingChemistryCrossover studyDifferential effectsSprintTorqueMuscle FatiguePhysical therapyCardiologyExercise Testhuman activitiesCycle ergometryMuscle ContractionJournal of science and medicine in sport
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Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women

2009

The purpose of this study was to examine the acute effect of resistance exercise (RE) on muscle androgen receptor (AR) and glucocorticoid receptor (GR) protein content. Fifteen resistance-trained men (n=8; 21+/-1 years, 175.3+/-6.7 cm, 90.8+/-11.6 kg) and women (n=7; 24+/-5 years, 164.6+/-6.7 cm, 76.4+/-15.6 kg) completed 6 sets of 10 repetitions of heavy squats. Blood samples were obtained before RE, after 3 and 6 sets of squats, and 5, 15, 30 and 70 min after RE. Muscle biopsies from the vastus lateralis were obtained before RE, and 10 min and 70 min after RE. Blood samples were analyzed for total and free testosterone concentrations and muscle samples were analyzed for AR and GR protein …

AdultMalemedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentClinical BiochemistryPhysical exerciseBiologyBiochemistrySteroidYoung AdultReceptors GlucocorticoidSex FactorsEndocrinologyGlucocorticoid receptorInternal medicinemedicineHumansTestosteroneMuscle SkeletalReceptorExerciseMolecular BiologyTestosteronePharmacologyOrganic ChemistryResistance trainingResistance TrainingAndrogenAndrogen receptorEndocrinologyReceptors AndrogenFemaleSteroids
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Effect of alkalosis on plasma epinephrine responses to high intensity cycle exercise in humans

2002

The purpose of this study was to determine the effects of alkalosis on epinephrine concentrations in response to a 90 s maximal exercise test. A group of ten healthy men ingested either a bicarbonate (BS) supplement (0.3 g x kg(-1) of body mass of sodium bicarbonate) or placebo mixture (P) prior to performing a 90 s maximal cycle ergometer test. An indwelling Teflon cannula was placed in the antecubital vein and blood samples were drawn at three times at rest separated by 10 min, immediately following the protocol, and at 2.5, 5, and 10 min post exercise to determine plasma epinephrine concentrations. Sodium bicarbonate ingestion significantly ( P0.05) induced alkalosis both at rest [mean (…

Adultmedicine.medical_specialtyAlkalosisEpinephrineBicarbonatePlacebochemistry.chemical_compoundPhysiology (medical)Internal medicineBlood plasmamedicineHumansIngestionOrthopedics and Sports MedicineLactic AcidChildAcid-Base EquilibriumSodium bicarbonatebusiness.industryPublic Health Environmental and Occupational HealthAlkalosisGeneral MedicineHydrogen-Ion Concentrationmedicine.diseaseBicyclingBicarbonatesEpinephrineEndocrinologychemistryPhysical EnduranceCatecholaminebusinessmedicine.drugEuropean Journal of Applied Physiology
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LONGITUDINAL TRACKING OF MUSCULAR POWER CHANGES OF NCAA DIVISION I COLLEGIATE WOMEN GYMNASTS

2004

Gymnastics relies upon power as a critical component of sports-specific fitness. The purpose of this study was to monitor long-term training adaptations in the power of National Collegiate Athletics Association Division I women gymnasts. Twenty members of a women's gymnastic team (aged 18-22) were tracked over 3 years with the first year a baseline year of testing. Whole body power for the counter-movement (CMJ) and squat (SJ) vertical jump was obtained via force plate analyses at 2 assessment time points during each year (February and November). Results showed significant (p < or = 0.05) and continued increases in peak power output in the CMJ and SJ at each biannual assessment. Improvement…

medicine.medical_specialtybusiness.industryPeak power outputSquatPhysical Therapy Sports Therapy and RehabilitationGeneral MedicineMuscular powerMuscle massVertical jumpFat free massPhysical therapymedicineTime to peakOrthopedics and Sports MedicineExercise physiologybusinessJournal of Strength and Conditioning Research
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Endogenous opioid peptide responses to opioid and anti-inflammatory medications following eccentric exercise-induced muscle damage.

2009

To determine the effects of Vicoprofen, Ibuprofen, and a placebo on the responses of endogenous opioid peptides following eccentric exercise-induced muscle damage 36 healthy men (age: 22.8 years; height: 178.8+/-6.2cm; body mass: 78.9+/-13.7kg; body fat: 15.8+/-6.5%) volunteered to participate in the study. Each participant was evaluated for pain 24h post and randomly assigned to an experimental group: VIC (Vicoprofen), IBU (Ibuprofen), or P (placebo). Medication was given four times daily (i.e., VIC (hydrocodone bitartrate 7.5mg with Ibuprofen 200mg) and IBU 200mg). Blood was obtained at rest and at 0, 24, 48, 72, 96 and 120h following the eccentric exercise damage protocol. No significant…

AdultMalemedicine.medical_specialtyAdolescentPhysiologyPhysical ExertionAnti-Inflammatory AgentsPainPhysical exercisePlaceboBiochemistryPlacebosCellular and Molecular NeuroscienceYoung AdultEndocrinologyDouble-Blind MethodInternal medicinemedicineEccentricAnimalsHumansOpioid peptideMuscle SkeletalExerciseEndogenous opioidPain MeasurementChemistryIbuprofenMagnetic Resonance ImagingEndocrinologymedicine.anatomical_structureOpioidOpioid PeptidesAdrenal medullamedicine.drugPeptides
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