0000000000124943

AUTHOR

Denis Nash

0000-0002-3280-5386

showing 4 related works from this author

Global, regional, and national levels and causes of maternal mortality during 1990-2013: A systematic analysis for the Global Burden of Disease Study…

2014

BACKGROUND: The fifth Millennium Development Goal (MDG 5) established the goal of a 75% reduction in the maternal mortality ratio (MMR; number of maternal deaths per 100,000 livebirths) between 1990 and 2015. We aimed to measure levels and track trends in maternal mortality, the key causes contributing to maternal death, and timing of maternal death with respect to delivery.METHODS: We used robust statistical methods including the Cause of Death Ensemble model (CODEm) to analyse a database of data for 7065 site-years and estimate the number of maternal deaths from all causes in 188 countries between 1990 and 2013. We estimated the number of pregnancy-related deaths caused by HIV on the basi…

PediatricsTime FactorsNutrition and Diseasehiv-infectionimmunodeficiency virus-1 infectionperipartum cardiomyopathyPoison controlHIV InfectionsIMMUNODEFICIENCY VIRUS-1 INFECTIONSocioeconomic FactorGlobal Health0302 clinical medicinePERIPARTUM CARDIOMYOPATHYpregnancy-related mortalityRisk FactorsPregnancyVoeding en ZiekteCause of DeathGlobal healthHIV Infection030212 general & internal medicinePregnancy Complications Infectious10. No inequalityCause of death030219 obstetrics & reproductive medicinesouth-africaMedicine (all)1. No povertyWOMENPREGNANCY-RELATED MORTALITYhealth initiativesGeneral MedicineSOUTH-AFRICA3. Good healthMaternal MortalityWorld HealthCHILD SURVIVALFemaleMaternal deathwomenHumanmedicine.medical_specialtyTime FactorDEATHSchild survivalArticleadult mortality03 medical and health sciencesAge DistributionHEALTH INITIATIVESSDG 3 - Good Health and Well-beingHIV-INFECTIONADULT MORTALITYInjury preventionmedicineOrganizational ObjectivesOrganizational ObjectiveHumansVLAGPregnancyModels Statisticalbusiness.industryRisk Factormedicine.diseasedeathsStandardized mortality ratioSocioeconomic FactorsRelative riskPregnancy Complications InfectioubusinessDemography
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Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

2016

BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015.METHODS: We estimated maternal mortality at the global, regional, and national levels from 1990 to 2015 for ages 10-54 years by systematically compiling and processing all available data sources from 186 of 195 countries and territories, 11 of which were analysed at the subnational level. We quantified eight underl…

0301 basic medicinePediatricsNutrition and DiseaseMILLENNIUM DEVELOPMENT GOALSSUSTAINABLE DEVELOPMENT GOALSANTENATAL CAREGlobal Health0302 clinical medicineVoeding en Ziekte11. SustainabilityGlobal healthHQHealthcare FinancingEMERGENCY OBSTETRIC CARE030212 general & internal medicineCooperative Behavior10. No inequalityReproductive healthMedicine(all)education.field_of_study030219 obstetrics & reproductive medicineMedicine (all)1. No povertyObstetrics and GynecologyPublic Health Global Health Social Medicine and EpidemiologyPrenatal CareGeneral Medicine11 Medical And Health SciencesLOW-RESOURCE SETTINGS3142 Public health care science environmental and occupational healthFamily Planning Service3. Good healthGBD 2015 Maternal Mortality CollaboratorsGovernment ProgramsMaternal MortalityReproductive HealthFamily Planning ServicesMaternal deathHEALTHLife Sciences & BiomedicineHumanCOUNTRIESmedicine.medical_specialtyPopulation610Prenatal careArticle03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingCASH TRANSFER PROGRAMEnvironmental healthGeneral & Internal Medicineparasitic diseasesmedicineLife ScienceQUALITYHumansGlobal Burden of Disease StudyeducationVLAGScience & TechnologyMedical Assistancebusiness.industryKlinisk medicinParturitionObstetric transitionmedicine.diseaseQPInfant mortalityFolkhälsovetenskap global hälsa socialmedicin och epidemiologiStandardized mortality ratio030104 developmental biologyRISK-FACTORSRGClinical MedicinebusinessRA
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Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for …

2015

Background Up-to-date evidence on levels and trends for age-sex-specific all-cause and cause-specific mortality is essential for the formation of global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013) we estimated yearly deaths for 188 countries between 1990, and 2013. We used the results to assess whether there is epidemiological convergence across countries. Methods We estimated age-sex-specific all-cause mortality using the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data. We generally estimated cause of death as in the GBD 2010. Key improvements included…

MaleAgingPediatricsNutrition and DiseaseDatabases FactualDisease030204 cardiovascular system & hematologyGlobal HealthMedical and Health SciencesDOUBLE-BLIND0302 clinical medicineAdolescent; Adult; Aged; Aged 80 and over; Cause of Death; Child; Child Mortality; Child Preschool; Databases Factual; Female; Global Health; Humans; Infant; Infant Newborn; Life Expectancy; Life Tables; Male; Middle Aged; Models Statistical; Mortality; Sex Distribution; Young AdultModelsVoeding en ZiekteCause of DeathEpidemiologyGlobal health80 and over2.2 Factors relating to the physical environmentLife Tables030212 general & internal medicineAetiologyChildINFLUENZAE TYPE-B11 Medical and Health SciencesCause of deathPediatricAged 80 and overPLACEBO-CONTROLLED-TRIALLife TableMortality rateMedicine (all)1. No povertyGeneral MedicineCHILDHOOD PNEUMONIAMiddle AgedStatistical3. Good healthInfectious DiseasesChild PreschoolPNEUMOCOCCAL CONJUGATE VACCINEChild MortalityFemaleInfectionLife Sciences & BiomedicineHumanAdultmedicine.medical_specialtyAdolescentINTEGRATED APPROACHCHILDREN YOUNGER187 COUNTRIESDatabase03 medical and health sciencesDatabasesYoung AdultMedicine General & InternalLife ExpectancyGeneral & Internal MedicinemedicineLife ScienceHumansMortalitySex DistributionPreschoolFactualVLAGAgedScience & TechnologyModels Statisticalbusiness.industryPreventionPOPULATION HEALTHInfant NewbornENTERIC MULTICENTERInfantGBD 2013 Mortality and Causes of Death CollaboratorsNewbornVerbal autopsyChild mortalityGood Health and Well BeingLife expectancyRISK-FACTORSbusiness2.4 Surveillance and distributionDemographyModel
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Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risk…

2015

Summary Background The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention. The GBD 2013 provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution. Methods Attributable deaths, years of life lost, years lived with disability, and disability-adjusted life-years (DALYs) have been estimated for 79 risks or clusters of risks using the GBD 2…

MaleFine particulate matterNutrition and DiseaseMESH : SanitationHealth BehaviorDiseasesMESH: Metabolic DiseasesMESH: Global Health030204 cardiovascular system & hematologyMESH: Risk AssessmentGlobal HealthMESH : Nutritional StatusMESH: Occupational Exposure0302 clinical medicineUnsafe SexMESH: Risk FactorsRisk FactorsVoeding en ZiekteMedicineAir-pollutionMESH : Female030212 general & internal medicineMESH : Risk AssessmentSanitationWasting2. Zero hungerFactors de risc en les malaltiesMedicine (all)[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologiePublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineMESH : Occupational DiseasesMESH: Nutritional StatusAll-cause mortalityMESH : Risk FactorshumanitiesEnvironmental Exposure; Female; Global Health; Health Behavior; Humans; Male; Metabolic Diseases; Nutritional Status; Occupational Diseases; Occupational Exposure; Risk Assessment; Risk Factors; Sanitation; Medicine (all)Tobacco smoking3. Good healthOccupational DiseasesNutritional StatuMESH : Occupational ExposureMESH : Metabolic DiseasesCohortFemalemedicine.symptomRisk assessmentBlood-pressureHumanMESH: Occupational DiseasesRisk factors in diseasesCoronary-heart-diseaseMESH : MaleMESH: Health BehaviorMESH: Environmental ExposureNutritional StatusPopulation healthBody-mass indexRisk Assessment03 medical and health sciencesHousehold cookingMetabolic DiseasesCardiovascular-diseaseEnvironmental healthGeneral & Internal MedicineOccupational Exposureparasitic diseasesLife ScienceMESH: SanitationHumansRisk factorMESH : Health BehaviorVLAGGBD2013MESH: Humansbusiness.industryRisk FactorGlobal Burden of Disease Study; 79 behavioural environmental and occupational and metabolic risksLong-term exposureMESH : HumansCAUSE-SPECIFIC MORTALITYEnvironmental ExposureMESH: MaleMetabolic DiseaseOccupational DiseaseFolkhälsovetenskap global hälsa socialmedicin och epidemiologiMALE BRITISH DOCTORSYears of potential life lostRelative riskMalaltiesMESH : Global HealthOUTDOOR AIR-POLLUTION[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusinessMESH : Environmental ExposureMESH: FemaleLancet
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