Multiplicity results for fourth order two-point boundary value problems with asymmetric nonlinearities

Attraction in n ‐dimensional differential systems from network regulation theory

Characteristic numbers of non‐autonomous emden‐fowler type equations

We consider the Emden‐Fowler equation x” = ‐q(t)|x|2εx, ε > 0, in the interval [a,b]. The coefficient q(t) is a positive valued continuous function. The Nehari characteristic number An associated with the Emden‐Fowler equation coincides with a minimal value of the functional [] over all solutions of the boundary value problem x” = ‐q(t)|x|2εx, x(a) = x(b) = 0, x(t) has exactly (n ‐ 1) zeros in (a, b). The respective solution is called the Nehari solution. We construct an example which shows that the Nehari extremal problem may have more than one solution. First Published Online: 14 Oct 2010

On modelling of artificial networks arising in applications

On attracting sets in artificial networks: cross activation

Mathematical models of artificial networks can be formulated in terms of dynamical systems describing the behaviour of a network over time. The interrelation between nodes (elements) of a network is encoded in the regulatory matrix. We consider a system of ordinary differential equations that describes in particular also genomic regulatory networks (GRN) and contains a sigmoidal function. The results are presented on attractors of such systems for a particular case of cross activation. The regulatory matrix is then of particular form consisting of unit entries everywhere except the main diagonal. We show that such a system can have not more than three critical points. At least n–1 eigenvalu…

On a Planar Dynamical System Arising in the Network Control Theory

We study the structure of attractors in the two-dimensional dynamical system that appears in the network control theory. We provide description of the attracting set and follow changes this set suffers under the changes of positive parameters µ and Θ.

Types and Multiplicity of Solutions to Sturm–Liouville Boundary Value Problem

We consider the second-order nonlinear boundary value problems (BVPs) with Sturm–Liouville boundary conditions. We define types of solutions and show that if there exist solutions of different types then there exist intermediate solutions also.

Dirichlet Boundary Value Problem for the Second Order Asymptotically Linear System

We consider the second order system x′′=f(x) with the Dirichlet boundary conditions x(0)=0=x(1), where the vector field f∈C1(Rn,Rn) is asymptotically linear and f(0)=0. We provide the existence and multiplicity results using the vector field rotation theory.

Mathematical Modelling of Leukemia Treatment

Leukemia is a cancer that can be treated in a variety of ways: chemotherapy, radiation therapy and stem cell transplant. Recovery rates for this disease are relatively high, the treatment itself has a painful effect on the body and is accompanied by numerous side effects that can persist years after the patient is cured. For this reason, efforts are underway worldwide to develop more selective therapies that will only affect leukemia cells and not healthy cells. Knowledge of developmental GRN is yet scarce, and it is early for a systematic comparative effort. We consider mathematical model of genetic regulatory networks. This model consists of a nonlinear system of ordinary differential equ…

Multiplicity of Solutions for Second Order Two-Point Boundary Value Problems with Asymptotically Asymmetric Nonlinearities at Resonance

Abstract Estimations of the number of solutions are given for various resonant cases of the boundary value problem 𝑥″ + 𝑔(𝑡, 𝑥) = 𝑓(𝑡, 𝑥, 𝑥′), 𝑥(𝑎) cos α – 𝑥′(𝑎) sin α = 0, 𝑥(𝑏) cos β – 𝑥′(𝑏) sin β = 0, where 𝑔(𝑡, 𝑥) is an asymptotically linear nonlinearity, and 𝑓 is a sublinear one. We assume that there exists at least one solution to the BVP.

Attracting sets in network regulatory theory

Modern telecommunication networks are very complex and they should be able to deal with rapid and unpredictable changes in traffic flows. Virtual Network Topology is used to carry IP traffic over Wavelength-division multiplexing optical network. To use network resources in the most optimal way, there is a need for an algorithm, which will dynamically re-share resources among all devices in the particular network segment, based on links utilization between routers. Attractor selection mechanism could be used to dynamically control such Virtual Network Topology. The advantage of this algorithm is that it can adopt to very rapid, unknown and unpredictable changes in traffic flows. This mechani…

On a three-dimensional neural network model

The dynamics of a model of neural networks is studied. It is shown that the dynamical model of a three-dimensional neural network can have several attractors. These attractors can be in the form of stable equilibria and stable limit cycles. In particular, the model in question can have two three-dimensional limit cycles.

Two-Dimensional Differential Systems with Asymmetric Principal Part

We consider the Sturm–Liouville nonlinear boundary value problem $$\displaystyle\begin{array}{rcl} \left \{\begin{array}{l} x^{\prime} = f(t,y) + u(t,x,y),\\ y^{\prime} = -g(t, x) + v(t, x, y), \end{array} \right.& & {}\\ \begin{array}{l} x(0)\cos \alpha - y(0)\sin \alpha = 0,\\ x(1)\cos \beta - y(1)\sin \beta = 0, \end{array} & & {}\\ \end{array}$$ assuming that the limits \(\lim _{y\rightarrow \pm \infty }\frac{f(t,y)} {y} = f_{\pm }\), \(\lim _{x\rightarrow \pm \infty }\frac{g(t,x)} {x} = g_{\pm }\) exist. Nonlinearities u and v are bounded. The system includes various cases of asymmetric equations (such as the Fucik one). Two classes of multiplicity results are discussed. The first one …

Networks Describing Dynamical Systems

Abstract We consider systems of ordinary differential equations that arise in the theory of gene regulatory networks. These systems can be of arbitrary size but of definite structure that depends on the choice of regulatory matrices. Attractors play the decisive role in behaviour of elements of such systems. We study the structure of simple attractors that consist of a number of critical points for several choices of regulatory matrices.

Qualitative Analysis of Differential, Difference Equations, and Dynamic Equations on Time Scales

and Applied Analysis 3 thank Guest Editors Josef Dibĺik, Alexander Domoshnitsky, Yuriy V. Rogovchenko, Felix Sadyrbaev, and Qi-Ru Wang for their unfailing support with editorial work that ensured timely preparation of this special edition. Tongxing Li Josef Dibĺik Alexander Domoshnitsky Yuriy V. Rogovchenko Felix Sadyrbaev Qi-Ru Wang

Multiplicity of solutions for two-point boundary value problems with asymptotically asymmetric nonlinearities

On Different Type Solutions of Boundary Value Problems

We consider boundary value problems of the type x'' = f(t, x, x'), (∗) x(a) = A, x(b) = B. A solution ξ(t) of the above BVP is said to be of type i if a solution y(t) of the respective equation of variations y'' = fx(t, ξ(t), ξ' (t))y + fx' (t, ξ(t), ξ' (t))y' , y(a) = 0, y' (a) = 1, has exactly i zeros in the interval (a, b) and y(b) 6= 0. Suppose there exist two solutions x1(t) and x2(t) of the BVP. We study properties of the set S of all solutions x(t) of the equation (∗) such that x(a) = A, x'1(a) ≤ x' (a) ≤ x'2(a) provided that solutions extend to the interval [a, b].

Planar systems with critical points: multiple solutions of two-point nonlinear boundary value problems

Abstract Two-point boundary value problems for the second-order ordinary nonlinear differential equations are considered. First, we consider the planar systems equivalent to equation x ″ = f ( x ) , where f ( x ) has multiple zeros and the respective system has centers and saddle points in various combinations. Estimations of the number of solutions are given. Then results are extended to nonautonomous equations which have superlinear behavior at infinity.

On a differential system arising in the network control theory

We investigate the three-dimensional dynamical system occurring in the network regulatory systems theory for specific choices of regulatory matrix { { 0, 1, 1 } { 1, 0, 1 } { 1, 1, 0 } } and sigmoidal regulatory function f(z) = 1 / (1 + e-μz), where z = ∑ Wij xj - θ. The description of attracting sets is provided. The attracting sets consist of respectively one, two or three critical points. This depends on whether the parameters (μ,θ) belong to a set Ω or to the complement of Ω or to the boundary of Ω, where Ω is fully defined set.

Multiple period annuli in Liénard type equations

Abstract We consider the equation x ″ x 1 − x 2 x ′ 2 + g ( x ) = 0 , where g ( x ) is a polynomial. We provide the conditions for existence of multiple period annuli enclosing several critical points.

Types of solutions and multiplicity results for two-point nonlinear boundary value problems

Abstract Two-point boundary value problems for the second-order ordinary nonlinear differential equations are considered. If the respective nonlinear equation can be reduced to a quasi-linear one with a non-resonant linear part and both equations are equivalent in some domain D , and if solutions of the quasi-linear problem lie in D , then the original problem has a solution. We then say that the original problem allows for quasilinearization. We show that a quasi-linear problem has a solution of definite type which corresponds to the type of the linear part. If quasilinearization is possible for essentially different linear parts, then the original problem has multiple solutions.

Remarks on GRN-type systems

Systems of ordinary differential equations that appear in gene regulatory networks theory are considered. We are focused on asymptotical behavior of solutions. There are stable critical points as well as attractive periodic solutions in two-dimensional and three-dimensional systems. Instead of considering multiple parameters (10 in a two-dimensional system) we focus on typical behaviors of nullclines. Conclusions about possible attractors are made.

Dynamical Models of Interrelation in a Class of Artificial Networks

The system of ordinary differential equations that models a type of artificial networks is considered. The system consists of a sigmoidal function that depends on linear combinations of the arguments minus the linear part. The linear combinations of the arguments are described by the regulatory matrix W. For the three-dimensional cases, several types of matrices W are considered and the behavior of solutions of the system is analyzed. The attractive sets are constructed for most cases. The illustrative examples are provided. The list of references consists of 12 items.

Oscillatory Solutions of Boundary Value Problems

We consider boundary value problems of the form $$\displaystyle\begin{array}{rcl} & x'' = f(t,x,x'), & {}\\ & x(a) = A,\quad x(b) = B,& {}\\ \end{array}$$ assuming that f is continuous together with f x and fx′. We study also equations in a quasi-linear form $$\displaystyle{x'' + p(t)x' + q(t)x = F(t,x,x').}$$ Introducing types of solutions of boundary value problems as an oscillatory type of the respective equation of variations, we show that for a solution of definite type, the problem can be reformulated in a quasi-linear form. Resonant problems are considered separately. Any resonant problem that has no solutions of indefinite type is in fact nonresonant. The ways of how to detect solut…