0000000000129174

AUTHOR

Boris Mizaikoff

showing 2 related works from this author

Modular Breath Analyzer (MBA): Introduction of a Breath Analyzer Platform Based on an Innovative and Unique, Modular eNose Concept for Breath Diagnos…

2021

Exhaled breath analysis for early disease detection may provide a convenient method for painless and non-invasive diagnosis. In this work, a novel, compact and easy-to-use breath analyzer platform with a modular sensing chamber and direct breath sampling unit is presented. The developed analyzer system comprises a compact, low volume, temperature-controlled sensing chamber in three modules that can host any type of resistive gas sensor arrays. Furthermore, in this study three modular breath analyzers are explicitly tested for reproducibility in a real-life breath analysis experiment with several calibration transfer (CT) techniques using transfer samples from the experiment. The experiment …

calibration transferComputer scienceRespiratory SystemPharmaceutical ScienceOrganic chemistrycorrelation alignment01 natural scienceseNoseAnalytical Chemistry0302 clinical medicineQD241-441DDC 570 / Life sciencesDrug Discoverybreath analysisSensortechnikdigestive oral and skin physiologyAtemgasanalyseMischoxideExhalationChemistry (miscellaneous)piecewise direct standardization030220 oncology & carcinogenesisElektronische NaseCalibrationMolecular MedicineMOX sensorsSpectrum analyzerAdolescentlow sensing chamber volumeReal-time computingstandard samplesbreath samplingArticleElectronic nose03 medical and health sciencesddc:570Breath testsCalibrationHumansddc:610Physical and Theoretical ChemistryReproducibilitybusiness.industry010401 analytical chemistryBreath samplingpattern recognitionBreath diagnosticsAtemluftModular design0104 chemical sciencesBreath analyzerBreath gas analysisbusinessBiosensing techniquesDDC 610 / Medicine & healthBiomarkersMolecules
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Towards the determination of isoprene in human breath using substrate-integrated hollow waveguide mid-infrared sensors

2014

Selected volatile organic compounds (VOCs) in breath may be considered biomarkers if they are indicative of distinct diseases or disease states. Given the inherent molecular selectivity of vibrational spectroscopy, infrared sensing technologies appear ideally suitable for the determination of endogenous VOCs in breath. The aim of this study was to determine that mid-infrared (MIR; 3-20 µm) gas phase sensing is capable of determining isoprene in exhaled breath as an exemplary medically relevant VOC by hyphenating novel substrate-integrated hollow waveguides (iHWG) with a likewise miniaturized preconcentration system. A compact preconcentrator column for sampling isoprene from exhaled breath …

Pulmonary and Respiratory MedicineDetection limitTime FactorsInfrared RaysTemperatureAnalytical chemistryInfrared spectroscopySignal Processing Computer-AssistedBiosensing TechniquesSubstrate (electronics)Reference StandardsHollow waveguidechemistry.chemical_compoundHemiterpenesBreath TestsBreath gas analysischemistryPentanesTemporal resolutionCalibrationButadienesCalibrationHumansIsopreneJournal of Breath Research
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