0000000000130644

AUTHOR

De Simone R

[Evaluation of resistance to activated protein C in myocardial infarction patients].

It is known that resistance to activated protein C (APCR), often associated with a single point mutation (Arg506--Gln) in the coagulation factor V gene (factor V Leiden), is the most frequent inherited abnormality of blood coagulation. It plays a key role as pathogenetic factor of venous thromboembolism, but its association with an increased risk of arterial thrombosis is uncertain. Aim of the present study was to evaluate the prevalence of APCR in men, who suffered myocardial infarction more than 6 months earlier and without cardiovascular risk factors (hypercholesterolemia, smoking, diabetes, obesity and hypertension).The study was carried on 20 men aged65 years who have suffered myocardi…

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Carthage's military installations of the First Punic War on Monte Pellegrino (Palermo)

The excavation in the park of Villa Belmonte (Monte Pellegrino, Palermo) has brought to light several warehouses, made with a “pseudo-frame” technique, probably with a straw roof, used for the storage of foodstuffs, given the large quantity of Punic-type amphorae found in situ, datable to around the middle of the third century BC. In addition, a section of road - about 3 m wide that proceeds in the direction of WNW- ESE, consisting of two layers of use - has been intercepted. We believe to have tracked down part of a strategic/military station used by the Carthaginian army during the crucial years of the First Punic War.

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Effect of moderate Sicilian red wines comsuption on inflammatory biomarkers of atherosclerosis

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Relationship between body fat distribution and blood disorders in patients with visceral obesity with and without diabetes mellitus

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Effects of moderate consumption of sicilian red wines on some cardiovascular risk factors

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One-year atorvastatin treatment in hypercholesterolemic patients with or without carotid artery disease.

Aim. Statins are the drugs of choice in heterozygous familial hypercholesterolemia (FH), which has a high risk of premature cardiovascular events including myocardial infarction, stroke, and surgical revascularization. Methods. A 1-year open-label study was conducted to test the efficacy and tolerability of Atorvastatin titrated to the target, in proven FH patients and to evaluate certain inflammatory parameters. One hundred and two FH patients (44 men and 58 women; mean age 58.7±3.6 years) were included in the study. After evaluation using the B-mode duplex scanning system of extracranial carotid arteries, the patients were divided into groups: Group 1 (15 men, 25 women) with carotid plaqu…

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Haemostatic and fibrinolytic abnormalities in obese patients and in patients with type 2 diabetes with metabolic syndrome

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One year atorvastatin treatment in patients with familial hypercholesterolrmia: effects on CRP and fibrinogen

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