0000000000133965

AUTHOR

Stephanie E. Combs

showing 2 related works from this author

Radiolucent Carbon Fiber–Reinforced Pedicle Screws for Treatment of Spinal Tumors: Advantages for Radiation Planning and Follow-Up Imaging

2016

Objective Surgical treatment of spinal tumors regularly includes spinal instrumentation with pedicle screws. Most modern pedicle screws are made of titanium alloy, which is associated with artifacts on postoperative imaging such as computed tomography and/or magnetic resonance imaging. These artifacts hamper radiation treatment planning and execution and follow-up imaging. Recently, carbon fiber–reinforced polyetheretherketone (CFRP) implants became available for posterior instrumentation with the aim to reduce imaging artifacts by implants. Methods Patients harboring spinal tumors underwent posterior stabilization using CFRP pedicle screws. Postoperative imaging was evaluated for implant a…

Malemedicine.medical_specialtyTomography Scanners X-Ray ComputedPolymersmedicine.medical_treatmentRadiodensityPolyethylene GlycolsBenzophenones03 medical and health sciences0302 clinical medicineCarbon FiberPedicle ScrewsHounsfield scalemedicineHumansSpinal ChordomaRadiation treatment planningAgedRetrospective StudiesAged 80 and overPostoperative CareSpinal NeoplasmsRadiotherapymedicine.diagnostic_testbusiness.industryMagnetic resonance imagingKetonesMiddle Agedequipment and suppliesmedicine.diseaseMagnetic Resonance ImagingCarbonSurgeryRadiation therapySpinal FusionTreatment Outcome030220 oncology & carcinogenesisFemaleSurgeryNeurology (clinical)RadiologyImplantChordomabusiness030217 neurology & neurosurgeryFollow-Up StudiesWorld Neurosurgery
researchProduct

Clinical microbeam radiation therapy with a compact source: specifications of the line-focus X-ray tube

2020

Highlights • Line-focus X-ray tubes are suitable for clinical microbeam radiation therapy (MRT). • A modular high-voltage supply safely enables high electron beam powers. • An electron accelerator was designed to generate an eccentric focal spot. • We simulated a peak-to-valley dose ratio above 20 for single-field MRT. • Microbeam arc therapy spares healthy brain tissue compared to single-field MRT.

Equivalent uniform doselcsh:Medical physics. Medical radiology. Nuclear medicineMaterials scienceCompact radiation sourcelcsh:R895-920Monte Carlo methodElectronlcsh:RC254-282030218 nuclear medicine & medical imaginglaw.inventionCompact Radiation Source ; Equivalent Uniform Dose ; Line-focus X-ray Tube ; Microbeam Arc Therapy ; Microbeam Radiation Therapy ; Modular High-voltage Supply03 medical and health sciences0302 clinical medicineOpticslawRadiology Nuclear Medicine and imagingFocal Spot SizeOriginal Research ArticleLine-focus X-ray tubeRange (particle radiation)Radiationbusiness.industryMicrobeam arc therapyMicrobeamHot cathodeModular high-voltage supplyX-ray tubeequipment and supplieslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens030220 oncology & carcinogenesisCathode raybusinessMicrobeam radiation therapyPhysics and Imaging in Radiation Oncology
researchProduct