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RESEARCH PRODUCT
Clinical microbeam radiation therapy with a compact source: specifications of the line-focus X-ray tube
Christoph MatejcekChristoph MatejcekKurt AulenbacherJohanna WinterJan J. WilkensStefan BartzschStephanie E. CombsMarek Galeksubject
Equivalent uniform doselcsh:Medical physics. Medical radiology. Nuclear medicineMaterials scienceCompact radiation sourcelcsh:R895-920Monte Carlo methodElectronlcsh:RC254-282030218 nuclear medicine & medical imaginglaw.inventionCompact Radiation Source ; Equivalent Uniform Dose ; Line-focus X-ray Tube ; Microbeam Arc Therapy ; Microbeam Radiation Therapy ; Modular High-voltage Supply03 medical and health sciences0302 clinical medicineOpticslawRadiology Nuclear Medicine and imagingFocal Spot SizeOriginal Research ArticleLine-focus X-ray tubeRange (particle radiation)Radiationbusiness.industryMicrobeam arc therapyMicrobeamHot cathodeModular high-voltage supplyX-ray tubeequipment and supplieslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens030220 oncology & carcinogenesisCathode raybusinessMicrobeam radiation therapydescription
Highlights • Line-focus X-ray tubes are suitable for clinical microbeam radiation therapy (MRT). • A modular high-voltage supply safely enables high electron beam powers. • An electron accelerator was designed to generate an eccentric focal spot. • We simulated a peak-to-valley dose ratio above 20 for single-field MRT. • Microbeam arc therapy spares healthy brain tissue compared to single-field MRT.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-04-01 | Physics and Imaging in Radiation Oncology |