0000000000136198

AUTHOR

Amparo Roig-bataller

showing 2 related works from this author

Decellularized tracheal prelamination implant: A proposed bilateral double organ technique

2021

Introduction In tracheal replacement transplantation, prelamination is a critical stage. Nowadays, the most widely used prelamination technique is the prethoracic fascia flap with lateral thoracic artery. We propose a flap based on the internal thoracic artery, which allows a relatively non-aggressive double organ implant, and we have tested its efficacy in decellularized tracheas. Material and methods Tracheas of albino New Zealand rabbits were decellularized following a protocol that uses detergents and cryogenization, sterilized with 1kGy gamma radiation and tutorized with a stent. Bilateral pedicled flaps made of pectoral fascia and a muscular component were harvested through a longitud…

Malemedicine.medical_specialtyBiomedical EngineeringMedicine (miscellaneous)BioengineeringInternal thoracic arteryBiomaterialsmedicine.arterymedicineAnimalsTransplantation HomologousBioprosthesisDecellularizationCell-Free SystemTissue EngineeringLateral thoracic arterybusiness.industryGeneral MedicineFasciaPedicled FlapSurgeryTracheaTransplantationairway animal immune tolerance models tissue engineering trachea transplantsmedicine.anatomical_structureRabbitsImplantbusinessPectoral fasciaArtificial Organs
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A Standardised Approach to the Biomechanical Evaluation of Tracheal Grafts

2021

[EN] The ideal tracheal substitute must have biomechanical properties comparable to the native trachea, but currently there is no standardised approach to evaluating these properties. Here we propose a novel method for evaluating and comparing the properties of tracheal substitutes, thus systematising both measurement and data curation. This system was tested by comparing native rabbit tracheas to frozen and decellularised specimens and determining the histological characteristics of those specimens. We performed radial compression tests on the anteroposterior tracheal axis and longitudinal axial tensile tests with the specimens anastomosed to the jaw connected to a measuring system. All ca…

Materials scienceVolume UnitBioengineeringtracheaBiochemistryMicrobiologyArticlebiomechanicsUltimate tensile strengthAnimalsHumansTissue engineeringBiomechanicsLongitudinal axisairway bioengineering biomechanics tissue engineering trachea transplantationMolecular BiologyTransplantationbioengineeringTissue ScaffoldsBiomechanicsrespiratory systemQR1-502Biomechanical PhenomenaTracheaTransplantationAirwayRadial compressionairwaytissue engineeringRabbitsBiomedical engineeringtransplantationBiomolecules
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