0000000000136704

AUTHOR

Hector I. Michelena

showing 4 related works from this author

Corrigendum to Patterns of ascending aortic dilatation and predictors of surgical replacement of the aorta: A comparison of bicuspid and tricuspid ao…

2020

The authors regret that the author name of Romano and Raffa are incorrect. The corrected author's name are Romano G and Raffa GM. The authors would like to apologise for any inconvenience caused.

Aortic dilatationAortic valveAortamedicine.medical_specialtybusiness.industrySettore ING-IND/34 - Bioingegneria Industrialeaorta bicuspid aortic valvemedicine.anatomical_structuremedicine.arteryInternal medicinemedicineCardiologyCardiology and Cardiovascular MedicinebusinessMolecular Biology
researchProduct

Patterns of ascending aortic dilatation and predictors of surgical replacement of the aorta: A comparison of bicuspid and tricuspid aortic valve pati…

2019

Abstract Background Predictors of thoracic aorta growth and early cardiac surgery in patients with bicuspid aortic valve are undefined. Our aim was to identify predictors of ascending aorta dilatation and cardiac surgery in patients with bicuspid aortic valve (BAV). Methods Forty-one patients with BAV were compared with 165 patients with tricuspid aortic valve (TAV). All patients had LV EF > 50%, normal LV dimensions, and similar degree of aortic root or ascending aorta dilatation at enrollment. Patients with more than mild aortic stenosis or regurgitation were excluded. A CT-scan was available on 76% of the population, and an echocardiogram was repeated every year for a median time of 4 ye…

0301 basic medicineAortic valveMalemedicine.medical_specialtyBicuspid aortic valveHeart Valve Diseases030204 cardiovascular system & hematologyThoracic aorta03 medical and health sciencesAortic aneurysm0302 clinical medicineBicuspid aortic valveAneurysmBicuspid Aortic Valve DiseaseAneurysm; Bicuspid aortic valve; Echocardiography; Repeated measures; Thoracic aortaInternal medicinemedicine.arterymedicineThoracic aortaHumansMolecular BiologyAortaAgedDyslipidemiasAortaTricuspid valvebusiness.industryAortic Valve StenosisMiddle Agedmedicine.diseaseAneurysmStenosis030104 developmental biologymedicine.anatomical_structureRepeated measureEchocardiographyAortic ValveHypertensioncardiovascular systemCardiologyFemaleTricuspid ValveRepeated measuresCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedDilatation PathologicFollow-Up Studies
researchProduct

Shear Stress and Aortic Strain Associations With Biomarkers of Ascending Thoracic Aortic Aneurysm

2019

This study aims to investigate the association of wall shear stress (WSS) and aortic strain with circulating biomarkers including matrix metalloproteinases (MMP), tissue inhibitors of metalloproteinase (TIMP), and exosomal level of microRNA (miRNA) in ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valve.A total of 76 variables from 125 patients with ascending aortic aneurysms were collected from (1) blood plasma to measure plasma levels of miRNAs and protein activity; (2) computational flow analysis to estimate peak systolic WSS and time-average WSS (TAWSS); and (3) imaging analysis of computed tomography angiography to determine aortic wall strain. Principal compo…

AdultMalePulmonary and Respiratory MedicineAortic valvemedicine.medical_specialtybicuspid aortic valveVascular Remodeling030204 cardiovascular system & hematologyMechanotransduction CellularThoracic aortic aneurysm03 medical and health sciencesAortic aneurysm0302 clinical medicineBicuspid aortic valveBicuspid Aortic Valve Diseaseascending thoracic aortic aneurysmMatrix Metalloproteinase 12medicine.arteryInternal medicineAscending aortamedicineHumansAortaAgedComputed tomography angiographyAortaTissue Inhibitor of Metalloproteinase-1Aortic Aneurysm Thoracicmedicine.diagnostic_testbusiness.industrybiomarkersSettore ING-IND/34 - Bioingegneria IndustrialeMiddle Agedmedicine.diseaseMicroRNAsLogistic ModelsBlood pressuremedicine.anatomical_structure030228 respiratory systemAortic Valvecardiovascular systemCardiologyFemaleSurgeryStress MechanicalMatrix Metalloproteinase 1Cardiology and Cardiovascular MedicinebusinessThe Annals of Thoracic Surgery
researchProduct

Speckle myocardial imaging modalities for early detection of myocardial impairment in isolated left ventricular non-compaction

2009

Objective To examine the hypothesis that speckle myocardial imaging (SMI) modalities, including longitudinal, radial and circumferential systolic (s) and diastolic (d) myocardial velocity imaging, displacement (D), strain rate (SR) and strain (S), as well as left ventricular (LV) rotation/torsion are sensitive for detecting early myocardial dysfunction in isolated LV non-compaction (iLVNC). Design and results Twenty patients with iLVNC diagnosed by cardiac magnetic resonance (15) or echocardiography (5) were included. Patients were divided into two groups: ejection fraction (EF)>50% (n=10) and EF≤50% (n=10). Standard measures of systolic and diastolic function including pulsed wave tissue D…

AdultMalemedicine.medical_specialtyDiastoleDoppler imagingechocardiography cardiomyopathy.ArticleVentricular Dysfunction LeftYoung AdultSpeckle patternInternal medicinemedicineHumansUltrasonographyObserver VariationIsolated Noncompaction of the Ventricular MyocardiumEjection fractionmedicine.diagnostic_testbusiness.industryArea under the curveReproducibility of ResultsStroke VolumeMagnetic resonance imagingStroke volumeMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolareMagnetic Resonance ImagingCirculatory systemCardiologyFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesHeart
researchProduct