THREE-DIMENSIONAL CULTURES AND CO-CULTURES OF ADULT RAT CARDIOMYOCYTES

3D cultures as an in vitro model to study human vasostatin-1 effects

Oxidative stress apoptosis in carcinogenesis: molecular players and interactions.

The effects of oxidative stress on neoplastic cell survival.

Effects of conjugated linoleic acid and endurance training on peripheral blood and bone marrow of trained mice

Fat supplements, es- pecially conjugated linoleic acid (CLA), are increasingly popular ergogenic aids among endurance athletes. To evaluate the im- portance of fat supplementation in the practice of endurance sports, we investigated the effects of CLA supplementation on body weight, muscle hypertrophy, peripheral blood composition, and bone marrow composition in healthy, young, endurance- trained mice. Young, healthy mice were subdivided into control, trained, and treated groups, according to their running atti- tudes. Training was performed over a period of 6 weeks on a treadmill, at a gradually increasing duration and speed. CLA- treated groups were gavaged with 0.425 mg·d 1 CLA supplemen…

Sicilian extra virgin olive oils: characterisics, packaging and shelf life

Altered electrical activity in duodenal muscle cells from mdx (dystrophic) mice.

Human recombinant vasostatin-1 may interfere with cell-extracellular matrix interactions

Vasostatin-1 (VS-1), the N-terminal fragment derived from the cleavage of chromogranin A (CgA), has been shown to exert several biological activities on several tissues and organs. Recently, it has been reported that human recombinant VS-1 (STA-CGA(1-78)) may alter myocardial contractility in eel, frog., and rat hearts. In this article we have explored if STA-CGA(1-78) can induce intracellular cascades interacting both with adhesion molecules and/or extracellular matrix (ECM), components, that is, involvement of the heat shock protein 90 (HSP90) and the endothelial NOS (eNOS), known to be implicated in signal transduction mechanisms affecting myocardial contractility. We used 3D cultured ad…

HSP90 AND ENOS PARTIALLY CO-LOCALIZE AND CHANGE CELLULAR LOCALIZATION IN RELATION TO DIFFERENT ECM COMPONENTS IN 2D AND 3D CULTURES OF ADULT RAT CARDIOMYOCYTES.

Nestin as a marker of adult rat cardiac cells

c-Kit positive cells isolated from Adult Rat Myocardium can organze them-selves into a tissue-like cell mass.

Effects of conjugated linoleic acid on bone marrow composition of endurance trained mice

Characterization of c-kit positive cardiac stem cells subpopulations obtained from adult rat myocardium