0000000000139806

AUTHOR

Guenther Witzke

showing 5 related works from this author

Treatment of Hereditary Angioedema with the Mutation c.988A>G (p.K330E) in the Plasminogen Gene

2020

business.industryImmunologyMutation (genetic algorithm)Plasminogen GeneHereditary angioedemamedicineImmunology and Allergymedicine.diseasebusinessMolecular biologyJournal of Allergy and Clinical Immunology
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Risk of laryngeal edema and facial swellings after tooth extraction in patients with hereditary angioedema with and without prophylaxis with C1 inhib…

2010

Objective Tooth extractions may trigger clinical symptoms of hereditary angioedema due to C1 inhibitor deficiency (HAE-C1-INH). The aim of this study was to determine how many tooth extractions were followed by symptoms of HAE-C1-INH in patients with and without preoperative short-term prophylaxis with C1 inhibitor concentrate. Study design Tooth extractions and clinical symptoms of HAE-C1-INH were determined from clinical record files of 171 patients with HAE-C1-INH. Results Facial swelling or potentially life-threatening laryngeal edema, or both, occurred in 124/577 tooth extractions (21.5%) without prophylaxis. Similar symptoms occurred in a fewer proportion of patients undergoing extrac…

LarynxAdultMalemedicine.medical_specialtyTime FactorsPremedicationComplement C1 Inactivator ProteinsLaryngeal EdemaChemopreventionC1-inhibitorRisk FactorsEdemamedicineEdemaHumansRisk factorGeneral DentistryRetrospective StudiesbiologyDose-Response Relationship Drugbusiness.industryAngioedemas HereditaryRetrospective cohort studyLaryngeal Edemamedicine.diseaseSurgerymedicine.anatomical_structureTreatment OutcomeOtorhinolaryngologyFaceHereditary angioedemaInjections IntravenousTooth Extractionbiology.proteinSurgeryPremedicationFemaleOral Surgerymedicine.symptombusinessComplement C1 Inhibitor ProteinFollow-Up StudiesOral surgery, oral medicine, oral pathology, oral radiology, and endodontics
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Severe Tongue Swellings In Hereditary Angioedema With A Specific Mutation In The Plasminogen Gene

2018

Pathologymedicine.medical_specialtymedicine.anatomical_structureTongueSpecific mutationbusiness.industryImmunologyPlasminogen GeneHereditary angioedemamedicineImmunology and Allergymedicine.diseasebusinessJournal of Allergy and Clinical Immunology
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Tamoxifen, a Trigger Factor of Hereditary Angioedema with Normal C1-INH with a Specific Mutation in the F12 Gene (HAE-FXII)

2016

medicine.medical_specialtyTrigger factorSpecific mutationbusiness.industryImmunologymedicine.diseaseEndocrinologyInternal medicineHereditary angioedemamedicineCancer researchImmunology and AllergybusinessGeneTamoxifenmedicine.drugJournal of Allergy and Clinical Immunology
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Hereditary Angioedema with Normal C1-INH with Versus without a Specific Mutation in the F12 Gene

2015

business.industrySpecific mutationImmunologyHereditary angioedemaImmunologymedicineImmunology and Allergymedicine.diseasebusinessGeneJournal of Allergy and Clinical Immunology
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