0000000000140857
AUTHOR
Stéphane Galland
Semantic oriented data structuration for MABS Application to BIM
International audience; This paper presents a multiagent-based simulation approach to qualify the usage of buildings from the design phase. Our approach combines ontology and evolution process based on machine learning algorithms. The ontology relies on semantic data structures for the representation of environment components, agent knowledge and all data generated during the simulation.
Between the Megalopolis and the Deep Blue Sky: Challenges of Transport with UAVs in Future Smart Cities
International audience; With the rapid increase of the world's urban population, the infrastructure of the constantly expanding metropolitan areas is undergoing an immense pressure. To meet the growing demands of sustainable urban environments and improve the quality of life for citizens, municipalities will increasingly rely on novel transport solutions. In particular, Unmanned Aerial Vehicles (UAVs) are expected to have a crucial role in the future smart cities thanks to their interesting features such as autonomy, flexibility, mobility, adaptive altitude, and small dimensions. However, densely populated megalopolises of the future are administrated by several municipals, governmental and…
Molecular cloning and characterization of the cDNA encoding the rat liver gamma-butyrobetaine hydroxylase
Carnitine biosynthesis from lysine and methionine involves five enzymatic reactions. gamma-butyrobetaine hydroxylase (BBH; EC 1.14. 11.1) is the last enzyme of this pathway. It catalyzes the reaction of hydroxylation of gamma-butyrobetaine to carnitine. The cDNA encoding this enzyme has been isolated and characterized. The cDNA contained an open reading frame of 1161 bp encoding a protein of 387 amino acids with a deduced molecular weight of 44.5 kDa. The sequence of the cDNA showed an important homology with the human cDNA recently isolated. Northern analysis showed gamma-butyrobetaine hydroxylase expression in the liver and in some extend in the testis and the epididymis. During this stud…
THE METAMODEL: A STARTING POINT FOR DESIGN PROCESSES CONSTRUCTION
The construction of ad-hoc design processes following the Situational Method Engineering (SME) paradigm is currently carried out by adopting a set of phases for which, until now, no well defined techniques and guidelines have been established. The consequence is that organizations are very dependent on method designers' skills. In this paper, we propose an approach based on SME for constructing customized agent oriented design processes. Our approach adopts the metamodel as the most important factor leading to the selection and assembly of method fragments and an algorithm for establishing the instantiation order of metamodel elements. The algorithm makes the proposed approach repeatable a…
Ontology-based multiagent systems using Inductive Recommendations - A new approach to qualify building use during the Design phase
International audience; In this paper we propose a new metamodel to represent data for mutliagent-based simulations. Using this model, we also propose a method to perform the qualification of a building as soon as it is designed. The metamodel relies on semantic structures and allows representing both agents and environment. The representation of the environment use two kind of data: semantic and geometry. The qualification relies, for its part, on reasoning systems.
A MAS metamodel-driven approach to process fragments selection
The construction of ad-hoc design processes is more and more required today. In this paper we present our approach for the construction of a new design process following the Situational Method Engineering paradigm. We mainly focus on the selection and assembly activities on the base of what we consider a key element in agent design processes: the MAS metamodel. The paper presents an algorithm establishing a priority order in the realization (instantiation) of MAS metamodel elements by the fragments that will compose the new process.
Carnitine transport into muscular cells. inhibition of transport and cell growth by mildronate
Carnitine is involved in the transfer of fatty acids across mitochondrial membranes. Carnitine is found in dairy and meat products, but is also biosynthesized from lysine and methionine via a process that, in rat, takes place essentially in the liver. After intestinal absorption or hepatic biosynthesis, carnitine is transferred to organs whose metabolism is dependent on fatty acid oxidation, such as heart and skeletal muscle. In skeletal muscle, carnitine concentration was found to be 50 times higher than in the plasma, implicating an active transport system for carnitine. In this study, we characterized this transport in isolated rat myotubes, established mouse C2C12 myoblastic cells, and …
Qualifying Building Information Models with Multi-Agent System
6 pages; International audience; This paper presents a new approach combining the 3D elements composing the environment of mobile agents with semantic descriptors from building information models. Our proposal is based on the IFC standard which is used in the field of Civil Engineering to build digital models of buildings during the design phase. The semantic of IFC objects composing the 3D environment is used to select and set up 3D objects and elements of simulation scenarios. The result of this process dynamically generates the input files to the JaSIM environment that performs the simulation.
SEMANTIC MANAGEMENT OF INTELLIGENT MULTI-AGENTS SYSTEMS IN A 3D ENVIRONMENT
8 pages; International audience; This paper presents a new approach combining the 3D elements composing the environment of mobile agents with semantic descriptors from Building Information Models. Our proposal is based on the IFC standard, which is used in the field of Civil Engineering to build digital models of buildings during the design phase. The semantic of IFC objects composing the 3D environment is used to select and set up 3D objects and elements of simulation scenarios. The result of this process dynamically generates the input files for the JaSIM environment that performs the simulation. These files deserve the representation of the virtual environment in which the simulation is …
An ontology-based metamodel for multiagent-based simulations
Multiagent-based simulations enable us to validate dierent use-case scenarios in a lot of application domains. The idea is to develop a realistic virtual environment to test particular domain-specic procedures. This paper presents our general framework for interactive multiagent-based simulations in virtual environments. The major contribution of this paper is the integration of the notion of ontology as a core element to the design process of a behavioral simulation. The proposed metamodel describes the concepts of a multiagent simulation using situated agents moving in a semantically enriched 3D environment. The agents perceive the geometric and semantic data in the surrounding environmen…
Beneficial effects of l-carnitine in myoblastic C2C12 cells
L-Carnitine is a key molecule in the transfer of fatty acid across mitochondrial membranes. Bioavailable L-carnitine is either provided by an endogeneous biosynthesis or after intestinal absorption of dietary items containing L-carnitine. After intestinal absorption or hepatic biosynthesis, L-carnitine is transferred to organs whose metabolism is dependent upon fatty acid oxidation, such as skeletal muscle. To cross the muscle plasma membrane, there are several transporters involved. Among those transporters, OCTN2 is actually the only one to have been clearly characterized. Zidovudine is a commonly used inhibitor of human immunodeficiency virus (HIV) replication. Zidovudine has many side e…
Towards a multi-agent model to prevent damage caused by cocoa mirids to cocoa pods
Agriculture in general and cocoa farm in particular is one of the primary sources of income for several African countries. Although quite useful for the development of Africa, cocoa production is faced with several challenges like the diseases of cocoa trees. Mirid (Sahlbergella singularis) is the worst pest affecting cocoa production across west Africa causing 30% to 40% of damage on cocoa production. It is difficult to control the mirids’ population and its impact on the cacao production. Related works on mirids studied the mirids population as a macroscopic entity without considering local interactions of individual mirids. These models did not consider the behaviours and the environment…
Using Semantics in the Environment for Multiagent-Based Simulation
In this chapter, we carry out an overview and analysis of the usage of semantics to enhance environments in the domain of multiagent-based simulations. Firstly, we take a look at what a multiagent system (MAS) is, and after that we look at the environment for these systems, and why semantics are required in it. Various propositions to put semantics in the environment for MAS are then reviewed, as well as the strengths and weaknesses for these approaches. These propositions are grouped together under two categories, regarding whether the proposed approach is based on only the environment or on both the agents and the environment. The paper is then concluded with findings that have emerged by…
An organisational approach to engineer emergence within holarchies
An open issue in self-organisation is how to engineer emergent behaviours. This issue is also of interest for engineering holonic multi-agent systems as any level of a holarchy is dependant of the emergent behaviours of its sub-levels. In order to tackle this specific feature of holonic multi-agent systems, the capacity concept which abstracts a know-how from its concrete realisation is introduced. The use of this concept is illustrated in this paper through a case study using the ASPECS development process which enables the analysis, design, implementation and deployment of holonic multi-agent systems and integrates the capacity as a core concept of it is underlying metamodel, called capac…
A Cyber-Physical System for Semi-autonomous Oil & Gas Drilling Operations
International audience; In Oil&Gas drilling operations and after reaching deep drilled depths, high temperature increases significantly enough to damage the down-hole drilling tools, and the existing mitigation process is insufficient. In this paper, we propose a Cyber-Physical System (CPS) where agents are used to represent the collaborating entities in Oil\&Gas fields both up-hole and down-hole. With the proposed CPS, down-hole tools respond to high temperature autonomously with a decentralized collective voting based on the tools' internal decision model while waiting for the cooling performed up-hole by the field engineer. This decision model, driven by the tools' specifications, aims t…
Thyroid hormone controls carnitine status through modifications of gamma-butyrobetaine hydroxylase activity and gene expression.
The carnitine system plays a key role in beta-oxidation of long-chain fatty acids by permitting their transport into the mitochondrial matrix. The effects of hypothyroidism and hyperthyroidism were studied on gamma-butyrobetaine hydroxylase (BBH), the enzyme responsible for carnitine biosynthesis in the rat. In rat liver, BBH activity was decreased in the hypothyroid state and increased in hyperthyroid animals. The modifications in BBH activity correlated with changes in the enzyme Vmax values. These changes were shown to be related to hepatic BBH mRNA abundance. Thyroid hormones are known to interact with lipid metabolism, in particular by increasing long-chain fatty acid oxidation through…