0000000000141214
AUTHOR
Inés Moragrega
Relationship between eating styles and temperament in an Anorexia Nervosa, Healtlhy Control, and Morbid Obesity female sample.
Contains fulltext : 127209.pdf (Publisher’s version ) (Closed access) Objectives: Eating styles have been studied in both Obesity (OB) and Eating Disorders (ED), but they have not been examined in these two weight conditions together. The present study explores differences in eating styles in an Anorexia Nervosa (AN) and OB sample, compared to Healthy Controls (HC), and it analyses their relationship with Body Mass Index (BMI) and personality traits. Method: The total sample consisted of 291 female participants (66 AN, 79 OB and 146 HC). Evaluation: Assessment measures included the Dutch Eating Behaviour Questionnaire-DEBQ- and the Temperament and Character Inventory-Revised-TCI-R-. Results…
Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies.
AbstractMedicinal plants and their extracts are natural remedies with enormous potential for treating various diseases, including depression and anxiety. In the case of depression, hundreds of plants have traditionally been used in folk medicine for generations. Different plant extracts and natural products have been analyzed as potential antidepressant agents with validated models to test for antidepressant-like effects in animals, although other complementary studies have also been employed. Most of these studies focus on the possible mediators implicated in these potential effects, with dopamine, serotonin, and noradrenaline being the principal neurotransmitters implicated, both through …
Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Human.
Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) and executive impairments. However, to date, no published reports establish the relationship between endocannabinoids, as biomarkers of the cannabinoid neurotransmission system, and executive functioning in humans. The aim of the present study was to explore the association between circulating levels of plasma endocannabinoids N-arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) and executive functions (decision making, response inhibition and cognit…
Motor activity in group-housed and isolated mice with short and long attack latencies: Effects of scopolamine
Isolation-induced behavioral changes are well described in mice, although few studies have investigated the involvement of the cholinergic system in these effects. It has also been suggested that mice that display short or long attack latencies show differences in their reactions to a novel environment. The purpose of the present study was, first, to investigate locomotor activity in grouped and isolated mice that displayed short or long attack latencies and, second, to evaluate locomotor activity to determine whether it was affected interactively by differential housing and scopolamine treatment. Two experiments were performed in which NMRI mice, either isolated or group housed, were used …
Effects of housing and nicotine on shuttle-box avoidance in male NMRI mice
The present study aimed to evaluate whether housing condition could interact with nicotine administration in influencing the acquisition of a two-way active avoidance task. Male NMRI mice were either group- or individually housed for 30 days and, after this period, evaluated both in the actimeter and, 24h later, in the elevated plus-maze. On the basis of the percentage of time spent in the open arms of the plus-maze, both group- and individually housed mice were sub-classified into three groups with high, moderate or low anxiety baseline levels. Effects of nicotine on the acquisition of the two-way active avoidance task was assessed in each of these groups of mice using an automated shuttle…
Early detection of the risk of developing psychiatric disorders: a study of 461 Chinese university students under chronic stress
Chronic stress, a characteristic of modern time, has a significant impact on general health. In the context of psychiatric disorders, insufficient coping behavior under chronic stress has been linked to higher rates of (1) depressive symptoms among subjects of the general population, (2) relapse among patients under treatment for clinical depression, and (3) negative symptoms among subjects with an elevated vulnerability to psychosis. In this normative study we assessed basic coping behavior among 461 Chinese freshman university students along with their consumption behavior and general health in terms of regular exercises, physical health, psychosomatic disturbances, and mental health. The…
An Internet-based program for depression using activity and physiological sensors: efficacy, expectations, satisfaction, and ease of use
Cristina Botella,1,2 Adriana Mira,1 Inés Moragrega,2,3 Azucena García-Palacios,1,2 Juana Bretón-López,1,2 Diana Castilla,1,2 Antonio Riera López del Amo,1 Carla Soler,1 Guadalupe Molinari,1 Soledad Quero,1,2 Verónica Guillén-Botella,2,3 Ignacio Miralles,1,2 Sara Nebot,1 Berenice Serrano,1,2 Dennis Majoe,4 Mariano Alcañiz,2,5 Rosa María Baños2,31Department of Basic, Clinical Psychology and Psychobiology, Universitat Jaume, Castellón, Spain; 2CIBER Physiopathology of Obesity and Nutrition, CIBERobn, Instituto de Salud Carlos III, Santiago de Compostela, Spain; 3Department o…
A User-Friendly Tool for Detecting the Stress Level in a Person s Daily Life
[EN] Mental health care represents over a third of the cost of health care to all EU nations and, in USA, it is estimated to be around the 2.5% of the gross national product. Depression and Stress related disorders are the most common mental illnesses. The European project OPTIMI will develop tools to make predictions through the early identification on the onset of the disease. In this paper, we present a user-friendly application developed in the OPTIMI project to detect the stress level in a person's daily life. The results of a first usability study of this application are also presented.
Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials
AbstractDepression is a syndrome characterized by deep sadness and the inhibition of psychic functions, sometimes accompanied by neurovegetative disorders, with symptoms of anxiety almost always present. The disease produces alterations in a variety of neural networks and neurotransmission systems, along with a dysfunction of the hypothalamic-pituitary-adrenal axis, which leads to concomitant alterations in the immunological response. Generally, there is a parallel increase in proinflammatory mediators as well as oxidative and nitrosative damage caused by a reduction of antioxidant defenses. In a previous review, we compiled and examined studies of medicinal plants that had been evaluated i…
Spatial learning in male mice with different levels of aggressiveness: effects of housing conditions and nicotine administration
The main aim of the present investigation was to evaluate the possible modulation of spatial learning ability by housing conditions and level of aggressiveness in mice, also testing whether differences in locomotion and anxiety could influence this relationship. Additionally, we have examined effects of nicotine in the acquisition and retention of a spatial learning task in groups of mice differing in these variables. NMRI male mice were either group-housed or individually housed for 30 days and then classified into mice with short (SAL) and long (LAL) attack latency after a pre-screening agonistic encounter. Locomotor activity and baseline levels of anxiety of these groups were evaluated i…
Phenolics as GABA-A receptor ligands:an updated review
Natural products can act as potential GABA modulators, avoiding the undesirable effects of traditional pharmacology used for the inhibition of the central nervous system such as benzodiazepines (BZD). Phenolics, especially flavonoids and phlorotannins, have been considered as modulators of the BZD-site of GABAA receptors (GABAARs), with sedative, anxiolytic or anticonvulsant effects. However, the wide chemical structural variability of flavonoids shows their potential action at more than one additional binding site on GABAARs, which may act either negatively, positively, by neutralizing GABAARs, or directly as allosteric agonists. Therefore, the aim of the present review is to compile and d…