0000000000143146

AUTHOR

Mario A. Isiordia-espinoza

showing 3 related works from this author

Patients with advanced oral squamous cell carcinoma have high levels of soluble E-cadherin in the saliva

2017

Background: The objective of this study was to assess the potential clinical value of the concentration of soluble salivary E-cadherin (sE-cadherin) compared with the clinical value of the resence of membranous E-cadherin (mE-cadherin) in oral squamous cell carcinoma tumor tissues. Material and Methods: Data regarding patient demographics, clinical stage, saliva and tumor tissue samples were collected. The saliva was analyzed for sE-cadherin protein levels and was compared to the mE-cadherin immunohistochemical expression levels in tumor tissues, which were assessed via the HercepTest® method. Patients without cancer were included in the study as a control group for comparisons of the sE-ca…

0301 basic medicineMalemedicine.medical_specialtySalivaE-cadher.inDiseaseGastroenterology03 medical and health sciences0302 clinical medicineInternal medicinemedicineCarcinomaHumansStage (cooking)SalivaGeneral DentistryLymph nodeNeoplasm StagingOral Medicine and PathologyCadherinbusiness.industryResearchOral cancerCancerMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Cadherins030104 developmental biologymedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellImmunohistochemistrySurgeryFemaleMouth Neoplasmsbusiness
researchProduct

Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery: A parallel, double-blind, randomized,…

2015

Background Preemptive analgesia is considered an alternative for treating the postsurgical pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic efficacy of oral ketorolac versus intramuscular tramadol after a mandibular third molar surgery. Material and Methods A parallel, double-blind, randomized, placebo-controlled clinical trial was carried out. Thirty patients were randomized into two treatment groups using a series of random numbers: Group A, oral ketorolac 10 mg plus intramuscular placebo (1 mL saline solution); or Group B, oral placebo (similar tablet to oral ketorolac) plus intramuscular tramadol 50 mg diluted in 1 mL saline solution. These tre…

Molarmedicine.medical_specialtymedicine.medical_treatmentAnalgesicPlacebolaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialDouble-Blind MethodlawmedicineHumansAdverse effectGeneral DentistrySalineTramadolPain MeasurementAnalgesicsPain Postoperativebusiness.industryResearchAnti-Inflammatory Agents Non-SteroidalTooth Impacted030206 dentistry:CIENCIAS MÉDICAS [UNESCO]SurgeryKetorolacbody regionsAnalgesics OpioidOtorhinolaryngologyAnesthesiaUNESCO::CIENCIAS MÉDICASSurgeryMolar ThirdTramadolOral SurgerybusinessKetorolac030217 neurology & neurosurgerymedicine.drugMedicina oral, patologia oral y cirugia bucal
researchProduct

Preemptive analgesic effectiveness of oral ketorolac plus local tramadol after impacted mandibular third molar surgery

2010

Objective: The aim of this study was to compare preemptive analgesia of oral ketorolac plus submucous local placebo with oral ketorolac plus submucous local tramadol after impacted mandibular third molar surgery. Study design: A double-blind, randomized, placebo-controlled clinical trial was conducted. Patients were randomized into two treatment groups (n = 15 per group): group A, oral ketorolac 10 mg, 30 minutes before surgery plus submucous local placebo (1 mL saline solution); group B, oral ketorolac 10 mg, 30 minutes before surgery plus submucous local tramadol (50 mg diluted in 1 mL saline solution). We evaluated the intensity of pain, time for the first analgesic rescue medication, an…

MaleMolarmedicine.medical_specialtyAdministration Topicalmedicine.medical_treatmentAnalgesicAdministration OralPlacebolaw.inventionYoung AdultDouble-Blind MethodRandomized controlled triallawStatistical significancemedicineHumansGeneral DentistrySalineTramadolPain Postoperativebusiness.industryAnti-Inflammatory Agents Non-SteroidalTooth Impacted:CIENCIAS MÉDICAS [UNESCO]SurgeryAnalgesics OpioidKetorolacOtorhinolaryngologyAnesthesiaUNESCO::CIENCIAS MÉDICASDrug Therapy CombinationFemaleMolar ThirdSurgeryTramadolbusinessKetorolacmedicine.drug
researchProduct