0000000000146983

AUTHOR

Olga V. Zaborova

0000-0003-1646-9981

showing 2 related works from this author

Complexes of star-shaped cationic polyelectrolytes with anionic liposomes: Towards multi-liposomal assemblies with controllable stability

2016

Abstract Complexes were formed via the electrostatic interaction between 30–50 nm anionic liposomes and a star-shaped polyelectrolyte, poly{[2-(methacryloyloxy)ethyl]trimethyl ammonium iodide}, having cationic arms that radiate from a silicon-based central core. The complexation was investigated with attention given to assessing the capacity of the cationic stars for the anionic liposomes (both liquid and solid); the integrity of the complexed liposomes; and the stability of the resulting star/liposome complexes in aqueous salt solutions. We have found that by changing the content of anionic groups in the liposomal membrane as well as the phase-state of membrane, the stability of star/lipos…

chemistry.chemical_classificationendocrine systemLiposomeAqueous solutionPolymers and PlasticsChemistryOrganic ChemistryCationic polymerizationSalt (chemistry)02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesPolyelectrolyteAmmonium iodide0104 chemical scienceschemistry.chemical_compoundMembranePolymer chemistryMaterials ChemistryOrganic chemistrySelf-assembly0210 nano-technologyPolymer
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Electrostatically Driven Complexation of Liposomes with a Star-Shaped Polyelectrolyte to Low-Toxicity Multi-Liposomal Assemblies

2013

Anionic liposomes are electrostatically complexed to a star-shaped cationic polyelectrolyte. Upon complexation, the liposomes retain their integrity and the resulting liposome-star complexes do not dissociate in a physiological solution with 0.15 M NaCl. This provides a multi-liposomal container for possible use as a high-capacity carrier.

endocrine systemLiposomePolymers and PlasticsLow toxicityChemistryCationic polymerizationBioengineeringPolyelectrolyteBiomaterialsStar polymerChemical engineeringMaterials ChemistryOrganic chemistryBiotechnologyMacromolecular Bioscience
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