6533b871fe1ef96bd12d2291

RESEARCH PRODUCT

Electrostatically Driven Complexation of Liposomes with a Star-Shaped Polyelectrolyte to Low-Toxicity Multi-Liposomal Assemblies

Andrey V. SybachinF.m. MengerNikolay S. Melik-nubarovAlexander A. YaroslavovDmitry V. PergushovAlexander B. ZezinFelix A. PlamperAxel H. E. MüllerOlga V. Zaborova

subject

endocrine systemLiposomePolymers and PlasticsLow toxicityChemistryCationic polymerizationBioengineeringPolyelectrolyteBiomaterialsStar polymerChemical engineeringMaterials ChemistryOrganic chemistryBiotechnology

description

Anionic liposomes are electrostatically complexed to a star-shaped cationic polyelectrolyte. Upon complexation, the liposomes retain their integrity and the resulting liposome-star complexes do not dissociate in a physiological solution with 0.15 M NaCl. This provides a multi-liposomal container for possible use as a high-capacity carrier.

https://doi.org/10.1002/mabi.201300436