0000000000149684
AUTHOR
Michael L. Hinni
Alteration of the Calcium Content in Inner Hair Cells of the Cochlea of the Guinea Pig after Acute Noise Trauma with and without Application of the Organic Calcium Channel Blocker Diltiazem
Calcium ions are known to be important to the process of signal transduction across the apical and basal sides of the inner hair cells. Calcium channel antagonists have been demonstrated by light microscopy to provide protection against acoustic trauma. To evaluate the protective effect of calcium channel blocker on the inner ear cells to noise exposure, the amount of the histochemical reaction products formed in the cytoplasm of the inner hair cells of the guinea pig after application of pyroantimonate was measured by an image processing system connected to an energy-filtering transmission electron microscope (EFTEM). Compared to untreated control specimens (experimental animal group I) th…
Objective measures of nasal function
Numerous techniques to objectively measure nasal function are available to the rhinologic surgeon. Rhinomanometry, acoustic rhinometry, laser Doppler flowmetry, saccharin transport time, determination of ciliary beat frequency, and olfactory and trigeminal event-related potentials are all techniques in current use. Rhinomanometry is the standard clinical tool used to indicate those patients complaining of nasal obstruction who are likely to benefit from septal and turbinate surgery. Acoustic rhinometry permits the precise localization of nasal stenoses and is the best predictor of a patient's postoperative satisfaction. It is, in addition, more sensitive than rhinomanometry in recording cha…
Effects of contralateral white noise stimulation on transitory evoked otoacoustic emissions in patients with acoustic neuroma.
Abstract Transitory evoked otoacoustic emissions are normal phenomena observed in most persons with hearing levels greater than 35 dB. Further, masking of the contralateral ear produces amplitude reductions in the transitory evoked otoacoustic emissions. We have undertaken a study of transitory evoked otoacoustic emissions in 20 patients with acoustic neuroma. All patients were assessed for transitory evoked otoacoustic emissions bilaterally, with and without contralateral masking with white band noise at 40, 50, and 60 dB. We found that transitory evoked otoacoustic emissions were present in 30% of ears with tumor and that the presence of transitory evoked otoacoustic emissions is associat…