0000000000149747

AUTHOR

Max J. Astrom

showing 4 related works from this author

Glucose regulation and pain in older people-The Helsinki Birth Cohort Study

2021

Aims: To assess if individuals with diabetes or prediabetes report more pain or have increased use of pain medication compared to normoglycaemic individuals. Methods: Using cross-sectional data, we studied 928 men and 1075 women from the Helsinki Birth Cohort Study in 2001-2004 at a mean age of 61.5 years. Glucose regulation was assessed with a 2-h 75 g oral glucose tolerance test, and applying World Health Organization criteria, participants were defined as having normoglycaemia, prediabetes (impaired fasting glucose or impaired glucose tolerance), newly diagnosed diabetes or previously diagnosed diabetes. Self-reported pain intensity and interference during the previous 4 weeks was estima…

Blood GlucoseMalePREDICTOREpidemiologyIMPACTEndocrinology Diabetes and MetabolismglukoosiaineenvaihduntaprediabetesDISEASECohort StudiesImpaired glucose tolerance0302 clinical medicinepain030212 general & internal medicinePrediabetesepidemiologiaPOPULATION2. Zero hungereducation.field_of_studyNutrition and DieteticsdiabetesDiabetesMiddle Aged3. Good healthPREVALENCEFemaleepidemiologyFamily Practiceikääntyneetmedicine.medical_specialtyPopulationPain030209 endocrinology & metabolismPrediabetic State03 medical and health sciencesInternal medicineDiabetes mellitusGlucose IntoleranceInternal MedicinemedicineHumansTOLERANCEeducationAgedbusiness.industryBeck Depression Inventorykipumedicine.diseaseImpaired fasting glucoseLIFEHIGH-RISKCross-Sectional StudiesGlucose3121 General medicine internal medicine and other clinical medicinekrooninen kipuBlood sugar regulationbusinessBody mass indexPrediabetesPERIPHERAL NEUROPATHY
researchProduct

Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study

2018

Aims To assess whether disturbances in glucose regulation are associated with impairment in physical performance during a 10-year follow-up. Methods 475 Men and 603 women from the Helsinki Birth Cohort Study were studied. Glucose regulation was evaluated with a 2-h 75-g oral glucose tolerance test (OGTT) in 2001-2004. Subjects were categorised as having either impaired fasting glucose (IFG), impaired glucose tolerance (IGT), newly diagnosed diabetes or previously known diabetes. Physical performance was assessed approximately 10 years later using the validated senior fitness test (SFT). The relationship between glucose regulation and the overall SFT score was estimated using multiple linear…

Blood GlucoseMaleAgingFITNESSEpidemiologyEndocrinology Diabetes and MetabolismPhysical fitnessCohort StudiesImpaired glucose toleranceMUSCLE STRENGTHDiabetes mellitus0302 clinical medicineEndocrinologyglukoosi-intoleranssiEpidemiology030212 general & internal medicineepidemiologiaFinlandAged 80 and overeducation.field_of_studyGlucose tolerance testdiabetesmedicine.diagnostic_testINDEPENDENCEGeneral Medicinefyysinen kuntodiabetes mellitusOriginal ArticleFemaleHEALTHmedicine.medical_specialtyBODY-COMPOSITIONPopulation030209 endocrinology & metabolismglucose tolerance testIMPAIRMENTSPrediabetic State03 medical and health sciencesUS ADULTSInternal medicineDiabetes mellitusGlucose IntoleranceInternal MedicinemedicineHumanseducationAgedbusiness.industryDISABILITYPhysical fitnessGlucose Tolerance Testmedicine.diseaseImpaired fasting glucoseHIGH-RISKAgeingikääntyminenverensokeri3121 General medicine internal medicine and other clinical medicineBlood sugar regulation3111 BiomedicinebusinessMEXICAN-AMERICANSFollow-Up StudiesActa Diabetologica
researchProduct

Telomere length and physical performance among older people-The Helsinki Birth Cohort Study.

2019

Telomere length has been suggested a biomarker of aging and is associated with several chronic diseases. However, the association between telomere length and physical performance is not well known. Using both cross-sectional and longitudinal data, we studied 582 women and 453 men from the Helsinki Birth Cohort Study at two time-points; a baseline examination in 2001-2004 at a mean age of 61 years and a follow-up examination approximately 10 years later in 2011-2013. Telomere length was measured both at baseline and at follow-up using real-time quantitative polymerase chain reaction. Physical performance was evaluated only at follow-up using the Senior Fitness Test (SFT), which assesses stre…

0301 basic medicineMaleAgingBLOODFITNESSEpidemiologybiomarkkeritCAPABILITY0302 clinical medicineMARKERSEpidemiologyMedicine2. Zero hungerSex CharacteristicsASSOCIATIONMiddle AgedTelomere3142 Public health care science environmental and occupational healthfyysinen kuntoPhysical functionBiomarker (medicine)Smoking statusepidemiologyFemaleHEALTHBirth cohortmedicine.medical_specialtyBIOMARKERSfyysinen toimintakyky03 medical and health sciencesphysical functionHumansFRAILTYAgedbusiness.industryMORTALITYDISABILITYagingbiomarkersTelomere HomeostasisTelomere030104 developmental biologyikääntyminenPhysical performancetelomeeritbusinessOlder peopleBody mass index030217 neurology & neurosurgeryDevelopmental BiologyDemographyFollow-Up StudiesMechanisms of ageing and development
researchProduct

Glucose regulation and grip strength in adults: Findings from the Helsinki Birth Cohort Study.

2021

Aim: this study aimed to assess the association between grip strength and glucose regulation in a cross-sectional setting.Methods: using data from the Helsinki Birth Cohort Study, 924 men and 953 women were studied at a mean age of 61.6 years. Grip strength was assessed in the dominant hand using a Newtest Grip Force dynamometer. A standard 2-h 75 g oral glucose tolerance test (OGTT) was used to define glucose regulation. The participants were classified into four groups: normoglycaemia, prediabetes (impaired fasting glucose or impaired glucose tolerance), newly diagnosed diabetes and previously known diabetes. The association between grip strength and glucose regulation was assessed using …

Blood GlucoseMaleAgingHealth (social science)EpidemiologyPhysical fitnesspuristusvoimaprediabetesImpaired glucose toleranceCohort StudiesMUSCLE STRENGTHGrip strengthDiabetes mellitus0302 clinical medicine030212 general & internal medicinePrediabetesepidemiologiakohorttitutkimusRISK2. Zero hungerdiabetesHand Strength3. Good healthfyysinen kuntodiabetes mellitusepidemiologyFemaleHEALTHmedicine.medical_specialtyPrediabetic State03 medical and health sciencesAGEDiabetes mellitusInternal medicinemedicineHumansOLDER-ADULTS030214 geriatricsbusiness.industryDIABETES-MELLITUSPhysical fitnessmedicine.diseaseImpaired fasting glucoseikääntyminenPHYSICAL-ACTIVITYCross-Sectional StudiesGlucoseDiabetes Mellitus Type 2Grip strengthMOBILITYgrip strength3121 General medicine internal medicine and other clinical medicinephysical fitnessBlood sugar regulationGeriatrics and GerontologybusinessPrediabetesGerontologyBody mass indexArchives of gerontology and geriatrics
researchProduct