0000000000149872

AUTHOR

P. Esposito

showing 4 related works from this author

Pegylated interferon α plus ribavirin for the treatment of chronic hepatitis C: A multicentre independent study supported by the Italian Drug Agency

2014

a b s t r a c t Background: Data on the efficacy of Peg-interferon/ribavirin therapy for chronic hepatitis C are mostly derived from treatment of selected patients enrolled in clinical trials. This study aimed to assess the effectiveness of Peg-interferon/ribavirin therapy in “real world” chronic hepatitis C patients in Italy. Methods: Independent observational multicentre study including consecutive patients receiving Peginterferon/ribavirin in the 18 months before (retrospective phase) and after (prospective phase) the start of the study. Results: 4176 patients were eligible. The final study population consisted of 2051 patients in the retrospective and 2073 in the prospective phase. Sust…

RegistrieMaleCirrhosismedicine.disease_causePolyethylene GlycolGastroenterologyPolyethylene Glycolschemistry.chemical_compoundHepatitis VirusesHepatitis ViruseProspective StudiesViralRegistriesChronicProspective cohort studyDrug CarrierDrug CarriersSettore MED/12 - GastroenterologiaMedicine (all)GastroenterologyRecombinant ProteinMiddle AgedHepatitis CRecombinant ProteinsTreatment OutcomeItalyCombinationRNA ViralPopulation studyDrug Therapy CombinationFemaleHumanmedicine.medical_specialtyGenotypeHepatitis C virusAlpha interferonRibavirin; Sustained virological response (SVR); TreatmentAntiviral AgentsFollow-Up StudieRibavirin; Sustained virological response (SVR); Treatment; Hepatology; GastroenterologyDrug TherapyInternal medicineRibavirinmedicineHumansAntiviral AgentHepatologybusiness.industryRibavirinInterferon-alphaHCV therapyHepatitis C ChronicHepatologymedicine.diseaseClinical trialTreatmentProspective StudiechemistryImmunologyRNARibavirin; Sustained virological response (SVR); Treatment; Antiviral Agents; Drug Carriers; Drug Therapy Combination; Female; Follow-Up Studies; Genotype; Hepatitis C Chronic; Hepatitis Viruses; Humans; Interferon-alpha; Italy; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; RNA Viral; Recombinant Proteins; Ribavirin; Treatment Outcome; RegistriesbusinessRibavirin; Sustained virological response (SVR); Treatment; Antiviral Agents; Drug Carriers; Drug Therapy Combination; Female; Follow-Up Studies; Genotype; Hepatitis C Chronic; Hepatitis Viruses; Humans; Interferon-alpha; Italy; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; RNA Viral; Recombinant Proteins; Ribavirin; Treatment Outcome; Registries; Gastroenterology; Hepatology; Medicine (all)Follow-Up StudiesSustained virological response (SVR)
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Surface–bottom relationships in the Gulf of Salerno (Tyrrhenian Sea) over the last 34 kyr: Compositional data analysis of palaeontological proxies an…

2009

The palaeontological, geochemical and mineralogical records of core GNS84-C106 were analysed in order to reconstruct palaeohydrological changes and palaeoproductivity patterns in the Gulf of Salerno for the last 34 kyr. This approach, including compositional analysis of planktonic and benthic assemblages, gave an insight into the relationships between continental, sea surface and bottom environmental changes. The main source of variability of planktonic and benthic assemblages is related respectively to sea surface temperature and palaeobathymetry. Interrelated changes in surface salinity, nutrients, density gradient in the water column and organic fluxes at the bottom act as a secondary fa…

Deep chlorophyll maximumbiologyfungiAnalisi dei dati composizionaliPaleontologybiology.organism_classificationgeochimicaForaminiferaBottom waterpaleoproduttivitàPaleontologyOceanographyWater columnMediterranean seaSpace and Planetary ScienceBenthic zoneGlacial periodgeographic locationsGeologyHoloceneGeobios
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A high resolution record of the last deglaciation in the southern Tyrrhenian Sea: environmental and climatic evolution.

2002

A multidisciplinary study was carried out on core C106 collected in the Salerno Gulf (southern Tyrrhenian Sea). Two tephra layers recovered in the core, N 18 O record of Globigerinoides ruber and Globigerina bulloides and seven 14 C calibrated ages provided the stratigraphic framework. The core sediments cover the last 28 kyr BP. Seismostratigraphic analysis of a high resolution acoustic profile, integrated by the dated core samples, allowed us to reconstruct the architecture and age of sedimentary bodies on the continental shelf. An integrated study based on different taxonomic groups (nannofossils, pteropods, foraminifera, and palynomorphs) provided palaeoclimatic trends, in agreement wit…

geographygeography.geographical_feature_categorybiologyContinental shelfGeologyGlobigerina bulloidesSapropelOceanographybiology.organism_classificationPaleontologyMediterranean seaOceanographyGeochemistry and PetrologyDeglaciationGlacial periodGlobigerinoidesHoloceneGeology
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XIPE: the x-ray imaging polarimetry explorer

2016

XIPE, the X-ray Imaging Polarimetry Explorer, is a mission dedicated to X-ray Astronomy. At the time of writing XIPE is in a competitive phase A as fourth medium size mission of ESA (M4). It promises to reopen the polarimetry window in high energy Astrophysics after more than 4 decades thanks to a detector that efficiently exploits the photoelectric effect and to X-ray optics with large effective area. XIPE uniqueness is time-spectrally-spatially- resolved X-ray polarimetry as a breakthrough in high energy astrophysics and fundamental physics. Indeed the payload consists of three Gas Pixel Detectors at the focus of three X-ray optics with a total effective area larger than one XMM mirror bu…

X-ray AstronomyHigh-energy astronomyPolarimetryX-ray opticsX-ray telescopeCondensed Matter Physic01 natural sciencesObservatory0103 physical sciencesPolarimetryElectronicOptical and Magnetic MaterialsSpectral resolutionElectrical and Electronic Engineering010303 astronomy & astrophysicsGas Pixel DetectorPhysicsX-ray astronomyta115X-ray optics010308 nuclear & particles physicsElectronic Optical and Magnetic MaterialApplied MathematicsVegaAstronomyComputer Science Applications1707 Computer Vision and Pattern RecognitionGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray opticsCondensed Matter PhysicsComputer Science ApplicationsApplied MathematicGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray optics; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications1707 Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringGas Pixel Detector; Polarimetry; X-ray Astronomy; X-ray optics; Electronic Optical and Magnetic Materials; Condensed Matter Physics; Computer Science Applications; Computer Vision and Pattern Recognition; Applied Mathematics; Electrical and Electronic EngineeringComputer Vision and Pattern RecognitionX-ray optic
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