0000000000150201

AUTHOR

Sara Vela

showing 3 related works from this author

Impact of Acute Hemoglobin Falls in Heart Failure Patients: A Population Study

2020

Aims: This study assessed the impact of acute hemoglobin (Hb) falls in heart failure (HF) patients. Methods: HF patients with repeated Hb values over time were included. Falls in Hb greater than 30% were considered to represent an acute episode of anemia and the risk of hospitalization and all-cause mortality after the first episode was assessed. Results: In total, 45,437 HF patients (54.9% female, mean age 74.3 years) during a follow-up average of 2.9 years were analyzed. A total of 2892 (6.4%) patients had one episode of Hb falls, 139 (0.3%) had more than one episode, and 342 (0.8%) had concomitant acute kidney injury (AKI). Acute heart failure occurred in 4673 (10.3%) patients, represent…

medicine.medical_specialtyAnemiaheart failurelcsh:Medicine030204 cardiovascular system & hematologyArticle03 medical and health sciences0302 clinical medicineInternal medicinemedicineRisk of mortality030212 general & internal medicineblood lossFirst episodebusiness.industryHazard ratiolcsh:RAcute kidney injuryGeneral Medicinemedicine.diseaseanemiamortalityConfidence interval3. Good healthacute kidney injuryConcomitantHeart failurebusinesshospitalizationJournal of Clinical Medicine
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Real-World Data of Anticoagulant Treatment in Non-valvular Atrial Fibrillation

2022

AimsTo assess the impact of anticoagulant treatment on risk for stroke and all-cause mortality of patients with atrial fibrillation using real-world data (RWD).MethodsPatients with prevalent or incident atrial fibrillation were selected throughout a study period of 5 years. Stroke, transitory ischemic attack, hemorrhagic stroke, and all-cause mortality were identified in the claims of the electronic health records (EHRs). Subjects were classified according to the anticoagulant treatment in four groups: untreated, vitamin K antagonists (VKAs), New Oral Anticoagulants (NOACs), and antiplatelet (AP). Risk of events and protection with anticoagulant therapy were calculated by Cox proportional h…

anticoagulant therapyRC666-701VKADiseases of the circulatory (Cardiovascular) systematrial fibrillationNOACsCardiovascular MedicineantiplateletCardiology and Cardiovascular MedicinestrokemortalityOriginal ResearchFrontiers in Cardiovascular Medicine
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Acute kidney injury in heart failure: a population study

2020

Abstract Aims The objective of the present study is to assess the prognostic value of acute kidney injury (AKI) in the evolution of patients with heart failure (HF) using real‐world data. Methods and results Patients with a diagnosis of HF and with serial measurements of renal function collected throughout the study period were included. Estimated glomerular filtration rate (GFR) was calculated with the CKD‐EPI (Chronic Kidney Disease Epidemiology Collaboration). AKI was defined when a sudden drop in creatinine with posterior recovery was recorded. According to the Risk, Injury, Failure, Loss, and End‐Stage Renal Disease (RIFLE) scale, AKI severity was graded in three categories: risk [1.5‐…

medicine.medical_specialtyRenal functionHeart failure030204 cardiovascular system & hematologyRisk of hospitalization03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineOriginal Research ArticlesRisk of mortalitymedicineHumansDiseases of the circulatory (Cardiovascular) system030212 general & internal medicineOriginal Research ArticleRetrospective StudiesFirst episodeCreatininebusiness.industryIncidence (epidemiology)Hazard ratioAcute kidney injurymedicine.disease3. Good healthAcute kidney injurychemistryRisk of mortalityCreatinineRC666-701CardiologyFemaleCardiology and Cardiovascular MedicinebusinessKidney diseaseGlomerular Filtration RateRenal functionESC Heart Failure
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