6533b7d1fe1ef96bd125cdaf

RESEARCH PRODUCT

Impact of Acute Hemoglobin Falls in Heart Failure Patients: A Population Study

Carlos BeaAdrian RuizCristina LopezAntonio FernandezSara VelaJosep RedonJosep RedonJose Luis HolgadoJavier GamezInmaculada SauriJose Luis TrilloRuth UsoAna FerrerJulio Núñez

subject

medicine.medical_specialtyAnemiaheart failurelcsh:Medicine030204 cardiovascular system & hematologyArticle03 medical and health sciences0302 clinical medicineInternal medicinemedicineRisk of mortality030212 general & internal medicineblood lossFirst episodebusiness.industryHazard ratiolcsh:RAcute kidney injuryGeneral Medicinemedicine.diseaseanemiamortalityConfidence interval3. Good healthacute kidney injuryConcomitantHeart failurebusinesshospitalization

description

Aims: This study assessed the impact of acute hemoglobin (Hb) falls in heart failure (HF) patients. Methods: HF patients with repeated Hb values over time were included. Falls in Hb greater than 30% were considered to represent an acute episode of anemia and the risk of hospitalization and all-cause mortality after the first episode was assessed. Results: In total, 45,437 HF patients (54.9% female, mean age 74.3 years) during a follow-up average of 2.9 years were analyzed. A total of 2892 (6.4%) patients had one episode of Hb falls, 139 (0.3%) had more than one episode, and 342 (0.8%) had concomitant acute kidney injury (AKI). Acute heart failure occurred in 4673 (10.3%) patients, representing 3.6/100 HF patients/year. The risk of hospitalization increased with one episode (Hazard Ratio = 1.30, 95% confidence interval (CI) 1.19&ndash

yearjournalcountryeditionlanguage
2020-06-15Journal of Clinical Medicine
10.3390/jcm9061869http://dx.doi.org/10.3390/jcm9061869