0000000000151820
AUTHOR
F Balsamo
Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery
Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…
Safety of hospital discharge before return of bowel function after elective colorectal surgery
Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…
Deformation mechanism and hydraulic properties of normal and strike-slip fault zones in porous carbonates outcropping in central and southern Italy.
Deformation of porous carbonate grainstones takes generally place by compactive shear banding, which initially produce single bands that may evolve during incremental strain into zones of multiple bands and, eventually, fault zones with discrete slip surfaces. The several processes associated to increased deformation are recorded in the aforementioned structural elements. In fact, they are characterized by a different texture, porosity, dimensional attributes (length, thickness, displacement). Fault zones are characterized by inner fault cores made of cataclastic material surrounded by thicker damage zones including single bands and zones of bands. In this work, we present the results of in…