0000000000152803

AUTHOR

A Ghosh

showing 6 related works from this author

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
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Safety of hospital discharge before return of bowel function after elective colorectal surgery

2020

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

operativeMalepostoperative dischargePostoperative Complications0302 clinical medicineColostomyCRITERIAProspective StudiesBowel functionColectomyIMAGINEstomaintestinesProctectomyIleostomydigestive oral and skin physiologypatient dischargecolorectal surgery hospital discharge bowel functionRECOVERYMiddle Agedadult; colostomy; elective surgical procedures; female; follow-up studies; humans; ileostomy; ileus; male; middle aged; multivariate analysis; patient discharge; patient readmission; patient safety; postoperative complications; prospective studies; recovery of function; colectomy; proctectomyPatient DischargeColorectal surgeryileus - - discharge - bowel function - elective - colorectal surgeryElective Surgical Procedures030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologyPatient SafetyCohort studysafetyAdultmedicine.medical_specialtyIleusPatient Readmissiondefecation03 medical and health sciencesIleuspostoperative complicationsmedicineHospital dischargeHumanscolorectal surgery; postoperative discharge; IMAGINE; stomacolorectal resectionColorectal resectiondefecation postoperative complications colorectal surgery intestines patient discharge patient readmission safety surgical procedures operative colorectal resection ileusbusiness.industryRecovery of FunctionOdds ratiomedicine.diseasedigestive system diseasessurgical proceduresSurgeryMultivariate AnalysisDefecationcolorectal surgerySurgerybusinessFollow-Up Studies
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Measurement of the Lund jet plane using charged particles in 13 TeV proton-proton collisions with the ATLAS detector

2020

The prevalence of hadronic jets at the LHC requires that a deep understanding of jet formation and structure is achieved in order to reach the highest levels of experimental and theoretical precision. There have been many measurements of jet substructure at the LHC and previous colliders, but the targeted observables mix physical effects from various origins. Based on a recent proposal to factorize physical effects, this Letter presents a double-differential cross-section measurement of the Lund jet plane using 139  fb−1 of √s=13  TeV proton-proton collision data collected with the ATLAS detector using jets with transverse momentum above 675 GeV. The measurement uses charged particles to ac…

:Kjerne- og elementærpartikkelfysikk: 431 [VDP]Protonshowers [parton]13000 GeV-cmsPhysics::Instrumentation and DetectorsHadronGeneral Physics and Astronomyjet: transverse momentumPhysical Effects01 natural sciencestransverse momentum [jet]High Energy Physics - ExperimentSubatomär fysikHigh Energy Physics - Experiment (hep-ex)Charged ParticlesSubatomic PhysicsComputingMilieux_COMPUTERSANDEDUCATIONscattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Parton showerNuclear ExperimentGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)PhysicsSettore FIS/01Jet (fluid)Large Hadron ColliderDouble Differential Cross SectionsDetectorhadronic [jet]Monte Carlo [numerical calculations]ATLASTransverse Momentacharged particleCharged particlemedicine.anatomical_structureCERN LHC Coll:Nuclear and elementary particle physics: 431 [VDP]colliding beams [p p]numerical calculations: Monte CarloParticle Physics - Experimentp p: scatteringCiências Naturais::Ciências Físicas530 Physicsformation [jet]Astrophysics::High Energy Astrophysical Phenomena:Ciências Físicas [Ciências Naturais]FOS: Physical sciencesMeasurements ofLHC ATLAS High Energy Physicsjet: formation530GeneralLiterature_MISCELLANEOUSMonte Carlo Modelparton: showersNuclear physicsdifferential cross section: measuredAtlas (anatomy)Fragmentationmeasured [differential cross section]0103 physical sciencesmedicineddc:530High Energy Physicsstructure010306 general physicsATLAS CollaborationScience & Technology010308 nuclear & particles physicsComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKSFísicajet: hadronic530 Physikangular resolutionProton Proton CollisionsElementary Particles and FieldsHigh Energy Physics::ExperimentDetector EffectsHadron-hadron collisionsp p: colliding beamsMathematicsofComputing_DISCRETEMATHEMATICSacceptanceexperimental results
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A Standard Siren Measurement of the Hubble Constant from GW170817 without the Electromagnetic Counterpart

2019

We perform a statistical standard siren analysis of GW170817. Our analysis does not utilize knowledge of NGC 4993 as the unique host galaxy of the optical counterpart to GW170817. Instead, we consider each galaxy within the GW170817 localization region as a potential host; combining the redshift from each galaxy with the distance estimate from GW170817 provides an estimate of the Hubble constant, $H_0$. We then combine the $H_0$ values from all the galaxies to provide a final measurement of $H_0$. We explore the dependence of our results on the thresholds by which galaxies are included in our sample, as well as the impact of weighting the galaxies by stellar mass and star-formation rate. Co…

AstrofísicaGravitacióCosmology and Nongalactic Astrophysics (astro-ph.CO)010504 meteorology & atmospheric sciencesStellar massStar (game theory)AstronomyFOS: Physical sciencesPREDICTIONSInterval (mathematics)AstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsAstronomy & AstrophysicsMASSdistance scale01 natural sciencessymbols.namesake0103 physical sciencesRange (statistics)distance scale; gravitational waves010303 astronomy & astrophysicsgravitational waveAstrophysics::Galaxy AstrophysicsQB0105 earth and related environmental sciencesPhysicsSettore FIS/01Science & TechnologyAstronomy and AstrophysicsAstronomy and AstrophysicRedshiftGalaxyWeightingGALAXIESdistance scale; gravitational waves; Astronomy and Astrophysics; Space and Planetary SciencePhysics and Astronomygravitational wavesSpace and Planetary SciencePhysical Sciencessymbols[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]STARSAstrophysics - Cosmology and Nongalactic AstrophysicsHubble's lawAstrophysical Journal Letters
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Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

2021

This international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). Average national Oxford COVID-19 Stringency Index scores were calculated to define the government response to COVID-19 for each patient for the period they awaited surgery, and classified into light restrictions (index 60). The primary outcome was the non-operation rate (defined as the proportion of patients who did not undergo planned surgery). Cox proportional-hazards regression models wer…

MaleCOVID-19 COVIDSURG COVIDSURG CANCEROutcome AssessmentIMPACTSettore MED/18 - CHIRURGIA GENERALEBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Surgery.surgeryCancer surgeryNeoplasms/classificationBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Surgical oncologyNeoplasmsAcute careCOVID-19 - epidemiologyOutcome Assessment Health CareMedicine and Health Sciences80 and overGlobal healthtimingProspective StudiesUK610 Medicine & healthProspective cohort studyCOVID-19/epidemiologyCOVIDAged 80 and overBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Oncology.BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Kirurgija.Hazard ratioArticlesMiddle AgedOncologyAdult; Aged; Aged 80 and over; Communicable Disease Control; COVID-19; Female; Humans; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; SARS-CoV-2; Time-to-Treatment; Withholding Treatment/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalecancer surgeryCovid-19Life Sciences & BiomedicineMENTAL-HEALTHmental healthCohort studyHumanAdultmedicine.medical_specialtydelay3122 CancersCOVID-19 - prevention and control610 Medicine & healthCOVIDSurg CollaborativeNOTime-to-TreatmentSDG 3 - Good Health and Well-beingLockdownmedicineHumanscancer1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryLS7_4Proportional Hazards ModelsAgedScience & Technologybusiness.industrySARS-CoV-2Public healthGeneral surgeryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.COVID-193126 Surgery anesthesiology intensive care radiologyHealth CareCommunicable Disease Control/legislation & jurisprudenceProspective StudieWithholding TreatmentCOVID-19; delay; SARS-CoV-2; surgery; timing; cancer surgery;COVID-19 ; lockdowns ; cancer surgeryCommunicable Disease ControlBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Onkologija.Proportional Hazards ModelNeoplasmbusiness
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Gravitational Waves and Gamma-Rays from a Binary Neutron Star Merger: GW170817 and GRB 170817A

2017

On 2017 August 17, the gravitational-wave event GW170817 was observed by the Advanced LIGO and Virgo detectors, and the gamma-ray burst (GRB) GRB 170817A was observed independently by the Fermi Gamma-ray Burst Monitor, and the Anticoincidence Shield for the Spectrometer for the International Gamma-Ray Astrophysics Laboratory. The probability of the near-simultaneous temporal and spatial observation of GRB 170817A and GW170817 occurring by chance is $5.0\times 10^{-8}$. We therefore confirm binary neutron star mergers as a progenitor of short GRBs. The association of GW170817 and GRB 170817A provides new insight into fundamental physics and the origin of short gamma-ray bursts. We use the ob…

AstrofísicaGravitacióneutron star: binaryclose [binaries]Astronomy[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]BATSE OBSERVATIONSgamma-ray burst: generalEQUIVALENCE PRINCIPLEEXTENDED EMISSIONastro-ph.HE; astro-ph.HEAstrophysicsKilonovageneral [gamma-ray burst]01 natural sciences7. Clean energyGeneral Relativity and Quantum Cosmologyphoton: velocityPROMPT EMISSIONLIGOclose gamma-ray burst: general gravitational waves [binaries]gravitational wave010303 astronomy & astrophysicsGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)BURST SPECTRAQCQBPhysicsastro-ph.HEHigh Energy Astrophysical Phenomena (astro-ph.HE)binaries: closeGRBEQUATION-OF-STATEviolation: Lorentzgamma ray: emissiongravitational wavesAstrophysics - High Energy Astrophysical PhenomenaGWradiation: electromagneticAfterglow Light CurvesAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic Astrophysicsgamma ray: burstinvariance: LorentzGW GRB LIGO Virgo Fermi BNSGLASTOptical Afterglows0103 physical sciencesgamma ray: detectorBinaries: close; gamma-ray burst: general; gravitational wavesSTFCFermi010308 nuclear & particles physicsGravitational waveVirgogravitational radiationRCUKAstronomy and AstrophysicsAstronomy and Astrophysictime delaysensitivityShapiro delayLIGORedshiftNeutron starVIRGOPhysics and AstronomyHOST GALAXYCPT VIOLATION13. Climate actiongravitationSpace and Planetary ScienceLUMINOSITY FUNCTIONVIEWING ANGLEbinaries: close; gamma-ray burst: general; gravitational waves; Astronomy and Astrophysics; Space and Planetary ScienceBNSspectrometerGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]redshift: measuredFermi Gamma-ray Space TelescopeAstrophysical Journal Letters
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