0000000000158165

AUTHOR

Carmela Maria Montone

0000-0002-2953-5696

showing 3 related works from this author

Stereoselective Synthesis of Spiro-Decalin Oxindole Derivatives via Sequential Organocatalytic Michael-Domino Michael/Aldol Reaction.

2022

A highly stereoselective procedure for the synthesis of spiro-polycyclic oxindoles bearing five contiguous stereogenic centers including two tetrasubstituted carbons has been developed. Under sequential organocatalysis performed by a pyrrolidine-based organocatalyst and DBU, a highly atom-economical Michael–domino Michael/aldol reaction sequence was optimized, yielding variously functionalized spiro-decalin oxindoles with excellent stereoselectivity (>99:1 dr, up to 92% ee). peerReviewed

kemiallinen synteesiAldehydesMolecular StructureOrganic Chemistryasymmetric organocatalysisdomino reactionssprio heterocyclesStereoisomerismNaphthalenesCatalysisOxindolesorgaaninen kemiaSpiro Compoundsasymmetric organocatalysis; oxindoles; sprio heterocycles; domino reactionsThe Journal of organic chemistry
researchProduct

Production and Characterization of Medium-Sized and Short Antioxidant Peptides from Soy Flour-Simulated Gastrointestinal Hydrolysate.

2021

Soybeans (Glycine max) are an excellent source of dietary proteins and peptides with potential biological activities, such as antihypertensive, anti-cholesterol, and antioxidant activity

peptidomicAntioxidantPhysiologymedicine.medical_treatmentClinical BiochemistryeducationPeptideRM1-950Fractionationantioxidative activity; bioactive peptides; mass spectrometry; peptidomics; soybean01 natural sciencesBiochemistryHydrolysateArticle0404 agricultural biotechnologymedicineDatabase search enginesoybeanMolecular Biologymass spectrometrychemistry.chemical_classification010401 analytical chemistryantioxidative activitypeptidomicsfood and beverages04 agricultural and veterinary sciencesCell Biology040401 food sciencehumanities0104 chemical sciencesAmino acidBiochemistrychemistrybioactive peptideGlycineTherapeutics. Pharmacologybioactive peptidesSoy flourAntioxidants (Basel, Switzerland)
researchProduct

CCDC 2165719: Experimental Crystal Structure Determination

2022

Related Article: Leonardo Straminelli, Francesco Vicentini, Antonio Di Sabato, Carmela Maria Montone, Chiara Cavaliere, Kari Rissanen, Francesca Leonelli, Fabrizio Vetica|2022|J.Org.Chem.|87|10454|doi:10.1021/acs.joc.2c01046

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters1-[(4-bromophenyl)methyl]-8'a-hydroxy-3'-nitro-2-oxo-4'-phenyl-123'4'4'a5'6'7'8'8'a-decahydro-1'H-spiro[indole-32'-naphthalene]-1'1'-dicarbonitrileExperimental 3D Coordinates
researchProduct