0000000000158166

AUTHOR

Chiara Cavaliere

0000-0003-1332-682x

showing 4 related works from this author

Stereoselective Synthesis of Spiro-Decalin Oxindole Derivatives via Sequential Organocatalytic Michael-Domino Michael/Aldol Reaction.

2022

A highly stereoselective procedure for the synthesis of spiro-polycyclic oxindoles bearing five contiguous stereogenic centers including two tetrasubstituted carbons has been developed. Under sequential organocatalysis performed by a pyrrolidine-based organocatalyst and DBU, a highly atom-economical Michael–domino Michael/aldol reaction sequence was optimized, yielding variously functionalized spiro-decalin oxindoles with excellent stereoselectivity (>99:1 dr, up to 92% ee). peerReviewed

kemiallinen synteesiAldehydesMolecular StructureOrganic Chemistryasymmetric organocatalysisdomino reactionssprio heterocyclesStereoisomerismNaphthalenesCatalysisOxindolesorgaaninen kemiaSpiro Compoundsasymmetric organocatalysis; oxindoles; sprio heterocycles; domino reactionsThe Journal of organic chemistry
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Production and Characterization of Medium-Sized and Short Antioxidant Peptides from Soy Flour-Simulated Gastrointestinal Hydrolysate.

2021

Soybeans (Glycine max) are an excellent source of dietary proteins and peptides with potential biological activities, such as antihypertensive, anti-cholesterol, and antioxidant activity

peptidomicAntioxidantPhysiologymedicine.medical_treatmentClinical BiochemistryeducationPeptideRM1-950Fractionationantioxidative activity; bioactive peptides; mass spectrometry; peptidomics; soybean01 natural sciencesBiochemistryHydrolysateArticle0404 agricultural biotechnologymedicineDatabase search enginesoybeanMolecular Biologymass spectrometrychemistry.chemical_classification010401 analytical chemistryantioxidative activitypeptidomicsfood and beverages04 agricultural and veterinary sciencesCell Biology040401 food sciencehumanities0104 chemical sciencesAmino acidBiochemistrychemistrybioactive peptideGlycineTherapeutics. Pharmacologybioactive peptidesSoy flourAntioxidants (Basel, Switzerland)
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Development of a Rapid LC-MS/MS Method for the Determination of Emerging Fusarium mycotoxins Enniatins and Beauvericin in Human Biological Fluids

2015

A novel method for the simultaneous determination of enniatins A, A1, B and B1 and beauvericin, both in human urine and plasma samples, was developed and validated. The method consisted of a simple and easy pretreatment, specific for each matrix, followed by solid phase extraction (SPE) and detection by high performance liquid chromatography-tandem mass spectrometry with an electrospray ion source. The optimized SPE method was performed on graphitized carbon black cartridges after suitable dilution of the extracts, which allowed high mycotoxin absolute recoveries (76%–103%) and the removal of the major interferences from the matrix. The method was extensively evaluated for plasma and urine …

AdultMaleElectrosprayHealth Toxicology and Mutagenesislcsh:MedicineToxicologyMass spectrometryTandem mass spectrometryArticleMatrix (chemical analysis)chemistry.chemical_compoundenniatinsFusariumLiquid chromatography–mass spectrometryLimit of DetectionTandem Mass SpectrometrymycotoxinsDepsipeptidesHumansSolid phase extractionliquid chromatography-tandem mass spectrometryplasmaAgedDetection limitChromatographylcsh:RbeauvericinSolid Phase ExtractionMiddle Agedbeauvericin; enniatins; liquid chromatography-tandem mass spectrometry; mycotoxins; plasma; urineBeauvericinurinechemistryFemaleChromatography LiquidToxins
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CCDC 2165719: Experimental Crystal Structure Determination

2022

Related Article: Leonardo Straminelli, Francesco Vicentini, Antonio Di Sabato, Carmela Maria Montone, Chiara Cavaliere, Kari Rissanen, Francesca Leonelli, Fabrizio Vetica|2022|J.Org.Chem.|87|10454|doi:10.1021/acs.joc.2c01046

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters1-[(4-bromophenyl)methyl]-8'a-hydroxy-3'-nitro-2-oxo-4'-phenyl-123'4'4'a5'6'7'8'8'a-decahydro-1'H-spiro[indole-32'-naphthalene]-1'1'-dicarbonitrileExperimental 3D Coordinates
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