0000000000161386

AUTHOR

Christian Hörtz

showing 2 related works from this author

Cylindrical Brush Polymers with Polysarcosine Side Chains: A Novel Biocompatible Carrier for Biomedical Applications

2015

Cylindrical brush polymers constitute promising polymeric drug delivery systems (nanoDDS). Because of the densely grafted side chains such structures may intrinsically exhibit little protein adsorption (“stealth” effect) while providing a large number of functional groups accessible for bioconjugation reactions. Polysarcosine (PSar) is a highly water-soluble, nonionic and nonimmunogenic polypeptoid based on the endogenous amino acid sarcosine (N-methyl glycine). Here we report on the synthesis, characterization and biocompatibility of cylindrical brush polymers with either polysarcosine side chains or poly-l-lysine-b-polysarcosine side chains. The latter leads to block copolypept(o)id based…

chemistry.chemical_classificationSarcosineBioconjugationPolymers and PlasticsBiocompatibilityOrganic ChemistryCationic polymerizationPolymerInorganic Chemistrychemistry.chemical_compoundPolymerizationchemistryPolymer chemistryMaterials ChemistrySide chainProtein adsorptionMacromolecules
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Preparation of Nanoporous MgAl2O4 by Combined Utilization of Sol-Gel Process and Combustion of Biorenewable Oil

2011

ABSTRACTNanoporous MgAl2O4 particulates with high porosities were successfully prepared from sol-gel reactions, solvent exchange with castor oil and subsequent combustion and calcination at 700 °C. The products were crystalline and semitransparent. Changes in the metal precursor concentrations allowed control of pore volumes from 0.7 to 1.1 cm3/g and average pore sizes from 14 to 19 nm. The specific surface areas are about 200 m2/g regardless of the precursor concentrations. After heating at 1000 °C for 10 hours, the products kept about 70% of their original pore volume and about 60% of the original surface area. Heating at 1100 °C caused a drastic reduction of pore volume and surface area …

Materials scienceNanoporousAerogellaw.inventionSolventVolume (thermodynamics)Chemical engineeringlawCastor oilmedicineOrganic chemistryCalcinationParticle sizeSol-gelmedicine.drugMRS Proceedings
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