0000000000161671

AUTHOR

Fermín Mayoral

showing 14 related works from this author

Research Letter: is neuroticism a risk factor for postpartum depression?

2012

Although the relationship between personality and depressive illness is complex (Shea, 2005), there is empirical evidence that some personality features such as neuroticism, harm avoidance, introversion, dependency, self-criticism or perfectionism are related to depressive illness risk (Gunderson et al. 1999). Moreover, personality traits, especially neuroticism, may explain the increased prevalence of depression among females (Goodwin & Gotlib, 2004). Few studies have explored neuroticism, extraversion and psychoticism as risk factors for depression after an event as stressful as childbirth. Pitt (1968) was the first author to report high scores on neuroticism and low scores on extraversio…

Postpartum depressionNeurotic DisordersDepresión postpartoEvaluación de la personalidad:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]medicine.disease_causePersonality Assessment:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]PregnancyRisk Factors62P ApplicationsBig Five personality traits:Psychiatry and Psychology::Mental Disorders::Neurotic Disorders [Medical Subject Headings]Applied Psychology:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]education.field_of_studyPerfectionism (psychology)Middle AgedNeuroticismPsychiatry and Mental healthMathematical statistics:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings]Harm avoidanceFemaleEstudios de seguimientoPsychology:Psychiatry and Psychology::Behavioral Disciplines and Activities::Personality Assessment [Medical Subject Headings]Factores de riesgoAdultmedicine.medical_specialtyAdolescent:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]PopulationEstadísticaDepression PostpartumYoung AdultPsychoticismCorrespondence:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies [Medical Subject Headings]medicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]Humans:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychiatric Status Rating Scales [Medical Subject Headings]Escalas de valoración psiquiátricaPsychiatryeducationPsychiatric Status Rating ScalesExtraversion and introversion:Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària [Àrees temàtiques de la UPC]:Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder::Depression Postpartum [Medical Subject Headings]medicine.diseaseLogistic Models:Check Tags::Female [Medical Subject Headings]Trastornos neuróticosFollow-Up Studies
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Efficacy of low-intensity psychological intervention applied by ICTs for the treatment of depression in primary care: a controlled trial

2015

Background: Depression is one of the most common disorders in Psychiatric and Primary Care settings and is associated with significant disability and economic costs. Low-intensity psychological interventions applied by Information and Communication Technologies (ICTs) could be an efficacious and cost-effective therapeutic option for the treatment of depression. The aim of this study is to assess 3 low-intensity psychological interventions applied by ICTs (healthy lifestyle, positive affect and mindfulness) in Primary Care; significant efficacy for depression treatment has previously showed in specialized clinical settings by those interventions, but ICTs were not used. Method: Multicenter c…

MaleMindfulnesshumanosPsychological interventiondepresiónlaw.invention:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Study ProtocolRandomized controlled trialClinical ProtocolslawEconomic costDepresión:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols [Medical Subject Headings]Young adultTratamiento asistido por ordenadorDepression (differential diagnoses)Primary health careDepressionPromoción de la saludadulto:Health Care::Health Services Administration::Patient Care Management::Comprehensive Health Care::Primary Health Care [Medical Subject Headings]adulto jovenPsychiatry and Mental healthPsicoterapiaRandomized controlled trialAtención plena:Health Care::Health Care Facilities Manpower and Services::Health Promotion [Medical Subject Headings]FemaleMindfulnessClinical psychologyAtención primaria de la saludAdultmedicine.medical_specialty:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychotherapy [Medical Subject Headings]:Check Tags::Male [Medical Subject Headings]Health Promotion:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Therapy Computer-Assisted [Medical Subject Headings]Young Adultatención plenaparasitic diseasesmedicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansPsychiatryComputer-delivered psychotherapypsicoterapia:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Mindfulness [Medical Subject Headings]protocolos clínicosbusiness.industryPsychotherapyHealth promotion:Check Tags::Female [Medical Subject Headings]Therapy Computer-AssistedProtocolos clínicosICTSbusiness:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Behavioral Symptoms::Depression [Medical Subject Headings]
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Efficacy of a blended low-intensity internet-delivered psychological programme in patients with multimorbidity in primary care: study protocol for a …

2019

BackgroundThe World Health Organization (WHO) has included comorbidity between depression and a chronic disease among the 10 leading global health priorities. Although there is a high prevalence of multimorbidity, health care systems are mainly designed for the management of individual diseases. Given the difficulty in delivering face-to-face psychological treatments, alternative models of treatment delivery have been proposed, emphasizing the role of technologies such as the Internet. The aim of this study is to assess the efficacy in Primary Care (PC) of a blended low-intensity psychological intervention applied using information and communication technologies (ICTs) for the treatment of …

MaleTecnología de la informaciónhumanosPsychological interventiondepresiónEnsayo clínico controlado aleatoriolaw.invention:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]dolor lumbarStudy Protocol0302 clinical medicineRandomized controlled triallawlcsh:PsychiatryDepresiónHealth careGlobal healthMedicine030212 general & internal medicineRandomized Controlled Trials as Topic:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Controlled Clinical Trials as Topic::Randomized Controlled Trials as Topic [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Clinical Trials as Topic::Controlled Clinical Trials as Topic::Randomized Controlled Trials as Topic [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]Depressionensayos clínicos controlados aleatorizados como asuntoMultimorbilidadadultoPrimary careLow back pain:Health Care::Health Services Administration::Patient Care Management::Comprehensive Health Care::Primary Health Care [Medical Subject Headings]Psychiatry and Mental healthdiabetes mellitus:Information Science::Information Science::Computing Methodologies::Computer Systems::Computer Communication Networks::Internet [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Pain::Back Pain::Low Back Pain [Medical Subject Headings]Femalemedicine.symptomAdultmedicine.medical_specialtyenfermedad crónicalcsh:RC435-571:Check Tags::Male [Medical Subject Headings]03 medical and health sciencesInformation and communication technologies (ICTs)Atención primaria de saludIntervention (counseling)Humans:Persons::Persons::Age Groups::Adult [Medical Subject Headings]:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]InternetPrimary Health Carebusiness.industry:Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings]Multimorbidity:Health Care::Health Care Facilities Manpower and Services::Health Personnel::Physicians::Physicians Primary Care [Medical Subject Headings]medicine.diseaseComorbidity030227 psychiatryClinical trial:Check Tags::Female [Medical Subject Headings]Diabetes Mellitus Type 2SpainChronic DiseasePhysical therapyRandomized controlled trial (RCT)business:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Behavioral Symptoms::Depression [Medical Subject Headings]Low Back PainBMC psychiatry
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La humanización en los planes de salud mental en España

2021

Resumen Introduccion La asistencia en salud mental (SM) presenta importantes retos, especialmente en el campo de la humanizacion. Los objetivos fueron identificar las medidas de humanizacion en los planes de SM de las comunidades autonomas (CC. AA.) espanolas y las prioridades a desarrollar en este ambito. Material y metodos Un grupo amplio y multidisciplinar de personas implicadas en la asistencia en SM participo en un consenso, segun un metodo Delphi modificado, basado en el «pensamiento de diseno», en 3 fases: 1) identificacion de medidas de humanizacion en los planes de SM de las CC. AA.; 2) analisis de la implantacion de estas medidas, y 3) identificacion de prioridades de humanizacion…

Psychiatry and Mental healthRevista de Psiquiatría y Salud Mental
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An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomized Controlled Trial.

2016

Background: Depression is the most prevalent cause of illness-induced disability worldwide. Face-to-face psychotherapeutic interventions for depression can be challenging, so there is a need for other alternatives that allow these interventions to be offered. One feasible alternative is Internet-based psychological interventions. This is the first randomized controlled trial (RCT) on the effectiveness of an Internet-based intervention on depression in primary health care in Spain. Objective: Our aim was to compare the effectiveness of a low-intensity therapist-guided (LITG) Internet-based program and a completely self-guided (CSG) Internet-based program with improved treatment as usual (iTA…

AdultMalemedicine.medical_specialty020205 medical informaticsmedicine.medical_treatmenthumanosMEDLINEPsychological interventiondepresiónHealth Informatics02 engineering and technologyPrimary carelaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawIntervention (counseling)0202 electrical engineering electronic engineering information engineeringmedicineHumansDepression (differential diagnoses)Original PaperInternetbusiness.industryDepressionRepeated measures designadultoInternet-based intervention030227 psychiatryCognitive behavioral therapySpainTherapy Computer-AssistedRandomized Controlled Trial (RCT)Physical therapyFemalebusinessClinical psychology
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Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized study

2013

Abstract Background Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. Methods The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/mod…

Research designMalemedicine.medical_treatmentCost-Benefit Analysis:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Methods::Research Design [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]law.invention:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Study ProtocolRandomized controlled trialQuality of lifeClinical Protocols:Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder::Depressive Disorder Major [Medical Subject Headings]law:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Clinical Protocols [Medical Subject Headings]Tratamiento asistido por ordenadorDepression (differential diagnoses)DepressionMiddle Aged:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychotherapy::Behavior Therapy::Cognitive Therapy [Medical Subject Headings]Psychiatry and Mental healthTreatment OutcomeResearch DesignRandomized controlled trial:Information Science::Information Science::Computing Methodologies::Computer Systems::Computer Communication Networks::Internet [Medical Subject Headings]FemaleAnálisis Costo-BeneficioPsychologyAdultmedicine.medical_specialtyPsychotherapist:Check Tags::Male [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Therapy Computer-Assisted [Medical Subject Headings]:Health Care::Health Care Economics and Organizations::Economics::Costs and Cost Analysis::Cost-Benefit Analysis [Medical Subject Headings]Trastorno depresivo mayor:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]medicineHumansPsychiatryComputer-delivered psychotherapy:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome [Medical Subject Headings]Depressive Disorder MajorInternetIntention-to-treat analysisCognitive Behavioral TherapyBeck Depression InventoryClinical trial:Check Tags::Female [Medical Subject Headings]Diseño de la investigaciónTherapy Computer-AssistedProtocolos clínicosCognitive therapyResultado del tratamientoTerapia cognitiva
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Adherence predictors in an Internet-based Intervention program for depression

2017

Internet-delivered psychotherapy has been demonstrated to be effective in the treatment of depression. Nevertheless, the study of the adherence in this type of the treatment reported divergent results. The main objective of this study is to analyze predictors of adherence in a primary care Internet-based intervention for depression in Spain. A multi-center, three arm, parallel, randomized controlled trial was conducted with 194 depressive patients, who were allocated in self-guided or supported-guided intervention. Sociodemographic and clinical characteristics were gathered using a case report form. The Mini international neuropsychiatric interview diagnoses major depression. Beck Depressio…

AdultMalemedicine.medical_specialtyAdolescent020205 medical informaticsPsychological intervention02 engineering and technologylaw.inventionprimary careYoung Adult03 medical and health sciences0302 clinical medicineRandomized controlled trialQuality of lifelawIntervention (counseling)0202 electrical engineering electronic engineering information engineeringHumansMedicineadherencePsychiatryCase report formDepression (differential diagnoses)AgedMini-international neuropsychiatric interviewPsychiatric Status Rating ScalesDepressive Disorder MajorInternetPrimary Health Carebusiness.industryBeck Depression InventoryMiddle AgedInternet-based intervention030227 psychiatryPsychotherapyClinical PsychologyTherapy Computer-AssisteddepressionQuality of LifePatient ComplianceFemalebusinessClinical psychologyCognitive Behaviour Therapy
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Association study of 44 candidate genes with depressive and anxiety symptoms in post-partum women.

2009

The post-partum period is a time of extreme vulnerability for a whole spectrum of psychiatric disorders. Delivery may be considered an important risk factor in genetically susceptible women. Five hundred and eight SNPs in 44 genes at candidate pathways putatively related to mood changes after delivery were genotyped in a multicenter cohort of 1804 women from Spain. Participants completed two scales at 2-3 days, 8 weeks, and 32 weeks post-partum, the Edinburgh Post-partum Depression Scale (EPDS) and the Spielberger State-Trait Anxiety Inventory (STAI). Those women who scored 9 or more on EPDS were evaluated for major depression using the Diagnostic Interview for Genetics Studies (DIGS) adapt…

Candidate genemedicine.medical_specialtyTime FactorsGenotypeAnxietyPolymorphism Single NucleotideWhite PeopleCohort StudiesDepression PostpartumInternal medicinePost-hoc analysisProtein Kinase C betamedicineHumansPsychiatryBiological PsychiatrySerotonin transporterDepression (differential diagnoses)Protein Kinase CRetrospective StudiesPsychiatric Status Rating ScalesSerotonin Plasma Membrane Transport ProteinsbiologyPostpartum PeriodRepeated measures designPsychiatry and Mental healthMoodSpainCohortbiology.proteinDopa DecarboxylaseAnxietyFemalemedicine.symptomPsychologyGenome-Wide Association StudyJournal of psychiatric research
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Coping strategies and postpartum depressive symptoms: A structural equation modelling approach.

2014

AbstractBackgroundVariables such as the mother's personality, social support, coping strategies and stressful events have been described as risk factors for postpartum depression. Structural Equation Modelling (SEM) analysis was used to examine whether neuroticism, perceived social support, perceived life events, and coping strategies are associated with postpartum depressive symptoms at the 8th and 32nd weeks.MethodsA total of 1626 pregnant women participated in a longitudinal study. Different evaluations were performed 8 and 32 weeks after delivery. Several measures were used: the Edinburgh Postnatal Depression Scale (EPDS), the Diagnostic Interview for Genetic Studies (DIGS), the Eysenck…

Postpartum depressionAdultCoping (psychology)Longitudinal studymedia_common.quotation_subjectStatistics as TopicPsychological TechniquesPersonality AssessmentDepression PostpartumLife Change EventsSocial supportPredictive Value of TestsPregnancyRisk FactorsAdaptation PsychologicalmedicinePersonalityHumansLongitudinal Studiesmedia_commonNeuroticismPostpartum PeriodSocial Supportmedicine.diseasePrognosisNeuroticismAnxiety DisordersEysenck Personality QuestionnairePsychiatry and Mental healthEdinburgh Postnatal Depression ScaleFemalePsychologyStress PsychologicalClinical psychologyEuropean psychiatry : the journal of the Association of European Psychiatrists
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Exploring the Relationship Between the Acceptability of an InternetBased Intervention for Depression in Primary Care and Clinical Outcomes: Secondary…

2019

Background: Depression is one of the most prevalent psychological disorders worldwide. Although psychotherapy for depression is effective, there are barriers to its implementation in primary care in Spain. The use of the Internet has been shown to be a feasible solution. However, the acceptability of Internet-based interventions has not been studied sufficiently. Objective: To assess the acceptability of an Internet-based intervention (IBI) for depression in primary care, and explore the relationship between expectations and satisfaction and the improvement in the clinical variables in primary care patients receiving this intervention. Furthermore, it offers data about the effects of some s…

lcsh:RC435-571media_common.quotation_subjectPsychological interventionSatisfactionlaw.invention03 medical and health sciencesprimary care0302 clinical medicineAcceptabilityRandomized controlled triallawIntervention (counseling)Perceptionacceptabilitylcsh:PsychiatryMedicineDepression (differential diagnoses)Original Researchmedia_commonPsychiatrybusiness.industryDepressionsatisfactionExpectationsPrimary careInternet-based intervention030227 psychiatry3. Good healthClinical trialPsychiatry and Mental healthdepressionAnxietyThe Internetmedicine.symptombusiness030217 neurology & neurosurgeryClinical psychologyexpectations
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Expectations, experiences and attitudes of patients and primary care health professionals regarding online psychotherapeutic interventions for depres…

2013

Abstract Background In the year 2020, depression will cause the second highest amount of disability worldwide. One quarter of the population will suffer from depression symptoms at some point in their lives. Mental health services in Western countries are overburdened. Therefore, cost-effective interventions that do not involve mental health services, such as online psychotherapy programs, have been proposed. These programs demonstrate satisfactory outcomes, but the completion rate for patients is low. Health professionals’ attitudes towards this type of psychotherapy are more negative than the attitudes of depressed patients themselves. The aim of this study is to describe the profile of d…

Médicos de atención primariaPsychological interventionActitud ante los ordenadoresActitud ante la salud:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Attitude::Attitude to Computers [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]DepresionStudy ProtocolCompletion rateProtocol:Health Care::Health Care Quality Access and Evaluation::Delivery of Health Care::Attitude to Health [Medical Subject Headings]Depression (differential diagnoses)Qualitative Researcheducation.field_of_studyOnline psychotherapyEntrevistas como asuntoAttitude to ComputersDepressionGrupos focales:Health Care::Health Care Quality Access and Evaluation::Delivery of Health Care::Attitude of Health Personnel [Medical Subject Headings]TelemedicinaFocus GroupsTelemedicinePsychiatry and Mental health:Health Care::Health Services Administration::Patient Care Management::Delivery of Health Care::Telemedicine [Medical Subject Headings]Attitude to Healthmedicine.medical_specialtyTelemedicineAttitude of Health Personnel:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychotherapy [Medical Subject Headings]PopulationInternet-based treatmentPhysicians Primary CareInterviews as TopicActitud del personal sanitariomedicineHumansPsychiatryeducationbusiness.industry:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Interviews as Topic::Focus Groups [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Interviews as Topic [Medical Subject Headings]:Health Care::Health Care Facilities Manpower and Services::Health Personnel::Physicians::Physicians Primary Care [Medical Subject Headings]:Disciplines and Occupations::Natural Science Disciplines::Science::Research::Empirical Research::Qualitative Research [Medical Subject Headings]Mental healthFocus groupPsychotherapyQualitative study:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Behavioral Symptoms::Depression [Medical Subject Headings]businessQualitative research
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Consumo de substancias durante el embarazo y dimensiones de personalidad

2020

Este estudio evalúa los patrones de consumo de substancias durante el embarazo y las dimensiones de personalidad asociadas, en una muestra multicéntrica de 1804 mujeres de población general. En el 2-3 día posparto, completaron una entrevista auto-administrada sobre el consumo de alcohol, tabaco, cafeína, cannabis, cocaína, opiáceos, drogas de diseño, además de variables socio-demográficas, obstétricas/reproductivas, historia psiquiátrica previa, apoyo social durante el embarazo y el cuestionario de personalidad de Eysenck (EPQ-RS). Se generaron modelos de regresión logística múltiple. La prevalencia del consumo fue del 50% (N=909): 40% cafeína, 21% tabaco, 3,5% alcohol, y 0,3 cannabis. Las …

Embarazomedia_common.quotation_subject030508 substance abuseMedicine (miscellaneous)03 medical and health sciencesSocial supportPsychiatric historyPsychoticismmedicinePersonalityPersonalidadmedia_commonCannabisPregnancyExtraversion and introversionbusiness.industryEstadística matemàtica--AplicacionsConsumo de substancias:62 Statistics::62P Applications [Classificació AMS]medicine.diseaseNeuroticismEysenck Personality QuestionnairePsychiatry and Mental healthMathematical statisticsCafeínaTabaco:Matemàtiques i estadística::Estadística matemàtica [Àrees temàtiques de la UPC]0305 other medical sciencebusinessAlcoholClinical psychology
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Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

2018

Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the application of polygenic risk scores to also highlight patterns of common genetic risk. We analyze polygenic risk scores for psychiatric disorders in a large pedigree (n ~ 260) in which 30% of family members suffer from major depressive disorder or bipolar disorder. Studying patterns of assortative mating and anticipation, it appears increased polygenic risk is contributed by affected individuals who married into the family, resulting in an increasing genetic risk over generat…

Netherlands Twin Register (NTR)0301 basic medicineMajor Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics ConsortiumBipolar DisorderSAMPLEMedicine (miscellaneous)Pedigree chartDisease0302 clinical medicineSCHIZOPHRENIA2.1 Biological and endogenous factorsMedicineAetiologyANTICIPATIONlcsh:QH301-705.5Psychiatry0303 health sciencesDepressionASSOCIATIONSerious Mental IllnessPeer reviewMental HealthSchizophrenia/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingMajor depressive disorderGeneral Agricultural and Biological SciencesEngineering sciences. Technologymedicine.medical_specialtyContext (language use)ArticlePsykiatriGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAGESDG 3 - Good Health and Well-beingddc:570Behavioral and Social Science/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_GeneticsPLINKGenetic TestingBipolar disorderPsychiatryBiology030304 developmental biologybusiness.industryPreventionHuman GenomeAssortative matingmedicine.diseaseBrain Disorders030104 developmental biologyMoodlcsh:Biology (General)Mood disordersAnticipation (genetics)ONSETHuman medicinebusiness030217 neurology & neurosurgery
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Subjective Perception of Cognitive Deficit in Psychotic Patients

2006

The objective of this study is to evaluate the subjective perception of cognitive deficit and how it relates to the perception of patients' relatives. Differences between the subjective perception of cognitive deficits in 107 DSM-IV-diagnosed psychotic patients and that of their relatives or caregivers were evaluated using the GEOPTE Scale. Fair agreement was observed between patient and family perception of cognitive functions, although there were important differences on those items that correspond to social functioning. A high degree of correlation was detected between the scores on this scale and clinical global impression scores, as well as the physicians' global impression of cognitiv…

AdultMalePersonality Inventorygenetic structuresPsychometricsAttitude of Health PersonnelHealth Statusmedia_common.quotation_subjectbehavioral disciplines and activitiesDevelopmental psychologySurveys and QuestionnairesPerceptionmedicineHumansCognitive deficitmedia_commonFamily HealthPsychiatric Status Rating ScalesPsychiatrySocial perceptionCognitive disorderCognitionAwarenessmedicine.diseaseDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthCaregiversPsychotic DisordersSocial PerceptionSchizophreniaClinical Global ImpressionFemalemedicine.symptomCognition DisordersPsychologyAttitude to HealthSocial Adjustmentpsychological phenomena and processesJournal of Nervous & Mental Disease
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