0000000000162005

AUTHOR

Márton Gelléri

showing 6 related works from this author

Nanoscale distribution of TLR4 on primary human macrophages stimulated with LPS and ATI

2019

Toll-like receptor 4 (TLR4) plays a crucial role in the recognition of invading pathogens. Upon activation by lipopolysaccharides (LPS), TLR4 is recruited into specific membrane domains and dimerizes. In addition to LPS, TLR4 can be stimulated by wheat amylase-trypsin inhibitors (ATI). ATI are proteins associated with gluten containing grains, whose ingestion promotes intestinal and extraintestinal inflammation. However, the effect of ATI vs. LPS on the membrane distribution of TLR4 at the nanoscale has not been analyzed. In this study, we investigated the effect of LPS and ATI stimulation on the membrane distribution of TLR4 in primary human macrophages using single molecule localization m…

LipopolysaccharidesSingle molecule localizationStimulationInflammation02 engineering and technology010402 general chemistry01 natural sciencesmedicineHumansDistribution (pharmacology)General Materials ScienceReceptorCells CulturedChemistryMacrophagesCell Membrane021001 nanoscience & nanotechnology0104 chemical sciencesCell biologyToll-Like Receptor 4MembraneMicroscopy FluorescenceTLR4lipids (amino acids peptides and proteins)Receptor clusteringmedicine.symptomTrypsin Inhibitors0210 nano-technologyNanoscale
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Back Cover: Nanographenes: Ultrastable, Switchable, and Bright Probes for Super‐Resolution Microscopy (Angew. Chem. Int. Ed. 1/2020)

2019

Materials scienceSuper-resolution microscopybusiness.industryOptoelectronicsCover (algebra)General ChemistrybusinessFluorescenceCatalysisAngewandte Chemie International Edition
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Nanographene: ultrastabile, schaltbare und helle Sonden für die hochauflösende Mikroskopie

2020

General Medicine
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High-resolution deep view microscopy of cells and tissues

2020

Abstract Methods, experimental setups and perspectives of three-dimensional deep view imaging microscopy of cell or tissue samples are reported. Preliminary biophysical and clinically relevant examples are presented.

Materials scienceNuclear magnetic resonanceAxial tomographyMicroscopyHigh resolutionStatistical and Nonlinear PhysicsElectrical and Electronic Engineering3d microscopySuperresolutionFluorescenceAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsQuantum Electronics
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Rücktitelbild: Nanographene: ultrastabile, schaltbare und helle Sonden für die hochauflösende Mikroskopie (Angew. Chem. 1/2020)

2019

General MedicineAngewandte Chemie
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Nanographenes: Ultrastable, Switchable, and Bright Probes for Super-Resolution Microscopy.

2019

Abstract Super‐resolution fluorescence microscopy has enabled important breakthroughs in biology and materials science. Implementations such as single‐molecule localization microscopy (SMLM) and minimal emission fluxes (MINFLUX) microscopy in the localization mode exploit fluorophores that blink, i.e., switch on and off, stochastically. Here, we introduce nanographenes, namely large polycyclic aromatic hydrocarbons that can also be regarded as atomically precise graphene quantum dots, as a new class of fluorophores for super‐resolution fluorescence microscopy. Nanographenes exhibit outstanding photophysical properties: intrinsic blinking even in air, excellent fluorescence recovery, and sta…

Materials sciencenanographenes010405 organic chemistrySuper-resolution microscopyGrapheneNanotechnologyGeneral ChemistryChromophore010402 general chemistry01 natural sciencesFluorescenceCatalysis0104 chemical scienceslaw.inventionlawQuantum dotSuper‐Resolution ImagingMicroscopyFluorescence microscopechromophoresfluorescenceblinkingResearch Articlessuper-resolution imagingResearch ArticleAngewandte Chemie (International ed. in English)
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