0000000000164137

AUTHOR

Sebastian Ludwig

0000-0002-5752-4951

showing 3 related works from this author

Impact of Proportionality of Secondary Mitral Regurgitation on Outcome After Transcatheter Mitral Valve Repair

2020

The purpose of this paper was to evaluate the impact of proportionality of secondary mitral regurgitation (SMR) in a large real-world registry of transcatheter edge-to-edge mitral valve repair (TMVr) BACKGROUND: Differences in the outcomes of recent randomized trials of TMVr for SMR may be explained by the proportionality of SMR severity to left ventricular (LV) volume.The ratio of pre-procedural effective regurgitant orifice area (EROA) to LV end-diastolic volume (LVEDV) was retrospectively assessed in patients undergoing TMVr for severe SMR between 2008 and 2019 from the EuroSMR registry. A recently proposed SMR proportionality scheme was adapted to stratify patients according to EROA/LVE…

medicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentRenal function030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicinemedicineNatriuretic peptideHumansRadiology Nuclear Medicine and imagingRetrospective StudiesBody surface areaMitral valve repairMitral regurgitationEjection fractionbusiness.industryMortality rateMitral Valve Insufficiencymedicine.diseaseTreatment OutcomeHeart failureQuality of LifeCardiologyMitral ValveCardiology and Cardiovascular MedicinebusinessJACC: Cardiovascular Imaging
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Impact of Residual Mitral Regurgitation on Survival After Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation.

2021

OBJECTIVES The aim of this study was to assess the impact of residual mitral regurgitation (resMR) on mortality with respect to left ventricular dilatation (LV-Dil) or right ventricular dysfunction (RV-Dys) in patients with secondary mitral regurgitation (SMR) who underwent mitral valve transcatheter edge-to-edge repair (TEER). BACKGROUND The presence of LV-Dil and RV-Dys correlates with advanced stages of heart failure in SMR patients, which may impact the outcome after TEER. METHODS SMR patients in a European multicenter registry were evaluated. Investigated outcomes were 2-year all-cause mortality and improvement in New York Heart Association functional class with respect to MR reduction…

medicine.medical_specialtyVentricular Dysfunction Right030204 cardiovascular system & hematologyNew york heart association03 medical and health sciences0302 clinical medicineInternal medicinemedicine.arteryMitral valvemedicineHumans030212 general & internal medicineCardiac Surgical Procedures610 Medicine & healthHeart FailureMitral regurgitationbusiness.industryMortality rateHazard ratioMitral Valve Insufficiencymedicine.diseaseConfidence intervalmedicine.anatomical_structureTreatment OutcomeHeart failurePulmonary arteryCardiologyCardiology and Cardiovascular MedicinebusinessJACC. Cardiovascular interventions
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Outcomes of transcatheter tricuspid valve intervention by right ventricular function: a multicentre propensity-matched analysis

2021

BACKGROUND Tricuspid regurgitation (TR) has a poor prognosis and limited treatment options and is frequently accompanied by right ventricular (RV) dysfunction. Transcatheter tricuspid valve interventions (TTVI) to reduce TR have been shown to be safe and feasible with encouraging early results. Patient selection for TTVI remains challenging, with the role of right ventricular (RV) function being unknown. AIMS The aims of this study were 1) to investigate survival in a TTVI-treated patient population and a conservatively treated TR population, and 2) to evaluate the outcome of TTVI as compared to conservative treatment stratified according to the degree of RV function. METHODS We studied 684…

medicine.medical_specialtyeducation.field_of_studyTricuspid valveVentricular functionbusiness.industryVentricular Dysfunction RightMortality rateHazard ratioPopulationTertiary careTricuspid Valve InsufficiencyTreatment Outcomemedicine.anatomical_structureInternal medicinePropensity score matchingCohortVentricular Function RightmedicineCardiologyHumansTricuspid ValveCardiology and Cardiovascular MedicineeducationbusinessEuroIntervention
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