0000000000164884
AUTHOR
Paolo Aiello
Concomitant Small Cell Neuroendocrine Carcinoma of Gallbladder and Breast Cancer
The neuroendocrine carcinoma is defined as a high-grade malignant neuroendocrine neoplasm arising from enterochromaffin cells, usually disposed in the mucosa of gastric and respiratory tracts. The localization in the gallbladder is rare. Knowledge of these gallbladder tumors is limited and based on isolated case reports. We describe a case of an incidental finding of small cell neuroendocrine carcinoma of the gallbladder, observed after cholecystectomy for cholelithiasis, in a 55-year-old female, who already underwent quadrantectomy and sentinel lymph-node biopsy for breast cancer. The patient underwent radiotherapy for breast cancer and six cycles of chemotherapy with cisplatin and etoposi…
Post-operative ileus in elderly patients
Materials and methods Data collected from 20 patients undergoing right hemicolectomy for right bowel cancer were evaluated. Patients included were divided in two groups of 10 subjects respectively, according their age. In the first group were allocated patients of age ≥ 70 years, whereas in the second group were included subjects of age ≤ 60 years. Patients affected by postoperative delirium or presenting complications that could altered the regain of intestinal motility were excluded. The time of first passage of flatus, the time of first defecation and the postoperative stay were evaluated.
Advancement flap in the management of chronic anal fissure: A prospective study
Lateral internal sphincterotomy is the surgical treatment of choice of chronic anal fissure after failure of conservative measures. Several randomized trials identified an overall risk of incontinence of 10 % mostly for flatus. Fissurectomy is the most commonly used procedure to preserve the integrity of the anal sphincters. However, a possible complication is keyhole defect that may lead to faecal soiling. In this study, chronic anal fissure (CAF) was treated by fissurectomy and anal advancement flap to preserve the anatomo-functional integrity of sphincters and to reduce healing time and the risk of anal stenosis. In patients with hypertonia, surgical treatment was combined with chemical …
Acute inflammatory response in the subcutaneous versus periprosthethic space after incisional hernia repair: an original article.
BACKGROUND: The acute inflammatory response following mesh implantation has been often evaluated in vitro and in animal models. The aim of this study was to evaluate the acute inflammatory response near the prosthesis in human by analysing some inflammatory indicators.METHODS: We used a cohort of twelve male patients affected by midline incisional hernia, who were admitted for surgical mesh repair. A suction drain was placed between the mesh and rectal muscles whereas, the other one was placed between the subcutaneous tissue and the oblique external sheath. The acute inflammatory response was analyzed by measuring the production of interleukin [IL]-1, IL-10, IL-1ra, C-Reactive Protein (CRP)…
Manometric Evaluation of Internal Anal Sphincter after Fissurectomy and Anoplasty for Chronic Anal Fissure: A Prospective Study
Chronic anal fissure (CAF) is a common painful clinical disease and its pathogenesis remains poorly understood. After failure of pharmacological therapy, that is the first-line treatment, surgical sphincterotomy remains the treatment of choice although it is followed by a high rate of anal incontinence resulting from the sphincter damage; therefore, the research of a sphincter-saving surgical option has become an important goal. The aim of this study was to evaluate the manometric modifications and the incidence of anal incontinence after fissurectomy and anoplasty with advancement skin flap in patients affected by CAF with hypertonia of the internal anal sphincter (IAS). Fifteen patients …
Quality of life in elderly patients after inguinal hernioplasty
Background and aim Inguinal hernia is the most frequent abdominal wall her- nias in elderly population. Surgical treatment must be aware of the cardiovascular and respiratory disease these patients are often affected by. Inguinal hernia is responsi- ble to impair the quality of life (QoL). Aim of this study was to evaluate the QoL through the Short-Form (SF)-36 questionnaire in a cohort of elderly patients undergoing inguinal hernioplasty. Materials and methods Fifteen male patients of age ≥75 years affected by sympto- matic unilateral uncomplicated inguinal hernia were included in this study. All patients undergoing inguinal hernioplasty in local anaesthesia according to the Liech- tenstei…
Improvement of quality of life in elderly after inguinal hernioplasty
Background Inguinal hernia represents one of the most common diseases in the elderly. It causes aching and unsightly swelling affecting quality of life (QOL), with a concomitant risk of strangulation. Despite this, an assumption of the risks of surgery may lead clinicians, particularly non-surgeons, to advise elderly patients against the repair of hernia, especially if asymptomatic [1]. The aim of this study was to evaluate QOL by a short Form 36 (SF-36) questionnaire [2] in elderly patients undergoing inguinal hernioplasty.