0000000000165007

AUTHOR

Corneliu Tudor

showing 6 related works from this author

Indocyanine Green-Enhanced Colorectal Surgery—between Being Superfluous and Being a Game-Changer

2020

Nowadays, surgical innovations incorporate new technological conquests and must be validated by evidence-based medicine. The use of augmented reality-assisted indocyanine green (ICG) fluorescence has generated a myriad of intraoperative applications such as demonstration of key anatomical landmarks, sentinel lymph nodes, and real-time assessment of local blood flow. This paper presents a systematic review of the clinical evidence regarding the applications of ICG near-infrared (NIR) fluorescence in colorectal surgery. After we removed duplicate publications and screened for eligibility, a total of 36 articles were evaluated: 23 on perfusion assessment, 10 on lymph node mapping, and 3 on int…

medicine.medical_specialtyindocyanine greenlymph node mappinganastomotic leaksClinical BiochemistrySentinel lymph nodeReview03 medical and health scienceschemistry.chemical_compound0302 clinical medicinenear-infrared (NIR) fluorescencemedicineNir fluorescenceLymph nodelcsh:R5-920Lymph node mappingbusiness.industryColorectal anastomosisColorectal surgeryDissectionmedicine.anatomical_structurechemistry030220 oncology & carcinogenesiscolorectal surgery030211 gastroenterology & hepatologyRadiologylcsh:Medicine (General)businessIndocyanine greenDiagnostics
researchProduct

Acute surgical abdomen during the COVID‑19 pandemic: Clinical and therapeutic challenges

2021

The present study investigated the effects of the COVID-19 pandemic on the clinical presentation and therapeutic management of acute surgical abdomen. A retrospective study of emergency hospitalizations with a diagnosis of acute surgical abdomen between April and July 2020 vs. a similar period in 2019 was performed. The observation sheets and the operating protocols were analyzed. Between April and July 2020, 50 cases of acute surgical abdomen were hospitalized and treated, compared to 43 cases in the same period last year. The main types of pathology in both groups included: Occlusions (60%, respectively 44.2% in 2019) and peritonitis (32%, respectively 41.8% in 2019). There was an increas…

0301 basic medicineCancer Researchmedicine.medical_specialtyAbdominal painbusiness.industryGeneral surgeryPerforation (oil well)PeritonitisRetrospective cohort studyArticlesGeneral Medicinemedicine.diseaseAsepsis03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureImmunology and Microbiology (miscellaneous)Acute abdomen030220 oncology & carcinogenesisPandemicmedicineAbdomenmedicine.symptombusinessExperimental and Therapeutic Medicine
researchProduct

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

2021

Multimodal treatment of breast cancer has made steady progress in recent years. The involvement of modern oncology, diagnostic imaging techniques and surgical treatment, have brought a definite benefit to patients, defining the multidisciplinary treatment of breast cancer. The introduction of immunohistochemical testing and genetic screening has led to the prioritization of therapy according to their results and a correct approach to initiating treatment. The main aim of the present study was to conduct a comparative analysis through a retrospective study of the therapeutic means used in breast cancer with the statistical evaluation of the obtained results. To carry out the study, a group o…

OncologyCancer Researchmedicine.medical_specialtyOncogenebusiness.industryCellPersonalized treatmentCancerArticlesGeneral MedicineCell cyclemedicine.diseaseMolecular medicinemedicine.anatomical_structureBreast cancerImmunology and Microbiology (miscellaneous)ApoptosisInternal medicinemedicinebusinessExperimental and Therapeutic Medicine
researchProduct

Acute Mesenteric Ischemia in COVID-19 Patients.

2022

Acute mesenteric ischemia is a rare but extremely severe complication of SARS-CoV-2 infection. The present review aims to document the clinical, laboratory, and imaging findings, management, and outcomes of acute intestinal ischemia in COVID-19 patients. A comprehensive search was performed on PubMed and Web of Science with the terms “COVID-19” and “bowel ischemia” OR “intestinal ischemia” OR “mesenteric ischemia” OR “mesenteric thrombosis”. After duplication removal, a total of 36 articles were included, reporting data on a total of 89 patients, 63 being hospitalized at the moment of onset. Elevated D-dimers, leukocytosis, and C reactive protein (CRP) were present in most reported cases, a…

hypercoagulabilitySARS-CoV-2RthromboemboembolismMedicineCOVID-19General MedicineReviewendothelitisacute mesenteric ischemiacytokinesJournal of clinical medicine
researchProduct

Significance of Neutrophil to Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) in Diabetic Foot Ulcer and Potential New Therapeutic Targets

2021

Diabetic foot ulcer (DFU) is a well-known complication of diabetes and a significant burden on the national health systems. The neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio are inexpensive and easily accessible biomarkers that have proved to be useful in several inflammatory, infectious and cardiovascular diseases. We carried out a comprehensive review examining the association of NLR and PLR with the onset and progression of DFU. PLR and NLR were significantly increased in patients with DFU, compared with a control group of T2DM patients without DFU, and correlate well with DFU severity, evaluated by Wagner and IWGDF grading scales. In patients with diabetic foot infect…

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentOsteomyelitisGeneral MedicineSystemic inflammationmedicine.diseaseGastroenterologyDiabetic foot ulcerAmputationDiabetes mellitusInternal medicinediabetes diabetic foot ulcer inflammation neutrophil-to-lymphocyte ratio (NLR) platelet lymphocyte ratio (PLR)medicineSurgeryClinical significancemedicine.symptomNeutrophil to lymphocyte ratioComplicationbusiness
researchProduct

Optimization of a GF-AAS method for lead testing in blood and urine: A useful tool in acute abdominal pain management in emergency.

2021

Suspicion of lead poisoning is confirmed by its concentration in blood and protoporphyrin red blood cells. At low concentrations, lead influences the synthesis of the heme in the sense of lowering it. Acute and chronic lead intoxication is extremely polymorphic in regards to its clinical manifestations, with digestive, hematological, cardiovascular, renal hepatic and neurological features. The aim of the study was to evaluate the presence of lead in human whole blood and urine harvested before and during chelation treatment in the case of lead poisoning. An atomic absorption spectroscopic method for the analysis of lead was developed using graphite furnace atomic absorption spectrophotomete…

Cancer Researchmedicine.medical_specialtybusiness.industryGeneral MedicineUrineArticlesmedicine.diseaseGastroenterologyLead poisoninglaw.inventionchemistry.chemical_compoundImmunology and Microbiology (miscellaneous)chemistrylawInternal medicineMedicineProtoporphyrinChelation therapybusinessGraphite furnace atomic absorptionLead (electronics)Atomic absorption spectroscopyWhole bloodExperimental and therapeutic medicine
researchProduct