IRIDE: Interdisciplinary research infrastructure based on dual electron linacs and lasers

This paper describes the scientific aims and potentials as well as the preliminary technical design of RUDE, an innovative tool for multi-disciplinary investigations in a wide field of scientific, technological and industrial applications. IRIDE will be a high intensity "particles factory", based on a combination of high duty cycle radio-frequency superconducting electron linacs and of high energy lasers. Conceived to provide unique research possibilities for particle physics, for condensed matter physics, chemistry and material science, for structural biology and industrial applications, IRIDE will open completely new research possibilities and advance our knowledge in many branches of sci…

Cavezzo, the first Italian meteorite recovered by the PRISMA fireball network. Orbit, trajectory, and strewn-field

ABSTRACT Two meteorite pieces have been recovered in Italy, near the town of Cavezzo (Modena), on 2020 January 4th. The associated fireball was observed on the evening of New Year’s Day 2020 by eight all-sky cameras of the PRISMA fireball network, a partner of FRIPON. The computed trajectory had an inclination angle of approximately 68° and a velocity at infinity of 12.8 km s−1. Together with the relatively low terminal height, estimated as 21.5 km, those values were indicating the significant possibility of a meteorite dropping event, as additionally confirmed by the non-zero residual total mass. The strewn-field was computed taking into account the presence of two bright light flashes, re…

The adipokine leptin a pleiotropic molecule in the human respiratory tract

Leptin, a 16-kd adipocyte-derived hormone originally described in metabolism regulation, plays a pleiotropic role in the immune system and inflammation (1). Leptin exerts its action through the leptin receptor (Ob-R), present in several tissues, human respiratory tract included. Leptin is a survival cytokine for human neutrophils and eosinophils (2, 3), other than for other cytotypes, included lung carcinoma cells (4). The following findings highlight the specific role of leptin both in the lung and in the nasal tract. We firstly find that ex-vivo leptin expression is increased and co-localized with lymphocytes T inflammatory cells, in bronchial mucosa of chronic obstructive pulmonary disea…

Micromaterials lipid-based for topic release of fluticasone propionate for the COPD treatment

Enhanced pulmonary delivery of Salmeterol Xinafoate (SX) by mucoadhesive microparticles

NEW RESULTS ON NONMESONIC WEAK DECAY OF Lambda HYPERNUCLEI WITH FINUDA

The FINUDA experiment has performed a systematic study of the NonMesonic Weak Decay (NMWD) of Λ hypernuclei analizing all the data collected from 2003 up to 2007. The results of a measurement of the spectra of protons coming from the NMWD of [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] are the subject of this paper.

Recent results on mesonic weak decay of Λ-hypernuclei

The FINUDA experiment has performed a systematic study of mesonic weak decay of p-shell Λ-hypernuclei. Recent results on the mesonic decay spectra and ratios are illustrated and discussed.

Time performance of a triple-GEM detector at high rate

Gaseous detectors are used in high energy physics as trackers or, more generally, as devices for the measurement of the particle position. For this reason, they must provide high spatial resolution and they have to be able to operate in regions of intense radiation, i.e. around the interaction point of collider machines. Among these, Micro Pattern Gaseous Detectors (MPGD) are the latest frontier and allow to overcome many limitations of the pre-existing detectors, such as the radiation tolerance and the rate capability. The gas Electron Multiplier (GEM) is a MPGD that exploits an intense electric field in a reduced amplification region in order to prevent discharges. Several amplification s…

FRIPON: a worldwide network to track incoming meteoroids

Context. Until recently, camera networks designed for monitoring fireballs worldwide were not fully automated, implying that in case of a meteorite fall, the recovery campaign was rarely immediate. This was an important limiting factor as the most fragile - hence precious - meteorites must be recovered rapidly to avoid their alteration. Aims. The Fireball Recovery and InterPlanetary Observation Network (FRIPON) scientific project was designed to overcome this limitation. This network comprises a fully automated camera and radio network deployed over a significant fraction of western Europe and a small fraction of Canada. As of today, it consists of 150 cameras and 25 European radio receiver…

Mesonic and Non-Mesonic Weak Decay of Hypernuclei with FINUDA

Abstract The FINUDA experiment performed a systematic study of both mesonic and non-mesonic weak decay of p - shell Λ-hypernuclei. Recent results on the mesonic decay rates and the non-mesonic decay ratios are illustrated and briefly discussed.

Electrochemical quantification of oxidative stress in airway epithelial cells

NLC Containing Fluticasone Propionate for Inhalatory Delivery: Biocompatibility and Drug Antiinflamatory Effect

New results on mesonic weak decay of p-shell Lambda-hypernuclei

The FINUDA experiment performed a systematic study of the charged mesonic weak decay channel of $p$-shell $\Lambda$-hypernuclei. Negatively charged pion spectra from mesonic decay were measured with magnetic analysis for the first time for ${^{7}_{\Lambda}Li}$, ${^{9}_{\Lambda}Be}$, ${^{11}_{\Lambda}B}$ and ${^{15}_{\Lambda}N}$. The shape of the $\pi^{-}$ spectra was interpreted through a comparison with pion distorted wave calculations that take into account the structure of both hypernucleus and daughter nucleus. Branching ratios $\Gamma_{\pi^{-}}/\Gamma_{tot}$ were derived from the measured spectra and converted to $\pi^{-}$ decay rates $\Gamma_{\pi^{-}}$ by means of known or extrapolate…