0000000000173807

AUTHOR

Jean-françois Guégan

0000-0002-7218-107x

showing 2 related works from this author

The macroecology of cancer incidences in humans is associated with large-scale assemblages of endemic infections.

2018

8 pages; International audience; It is now well supported that 20% of human cancers have an infectious causation (i.e., oncogenic agents). Accumulating evidence suggests that aside from this direct role, other infectious agents may also indirectly affect cancer epidemiology through interactions with the oncogenic agents within the wider infection community. Here, we address this hypothesis via analysis of large-scale global data to identify associations between human cancer incidence and assemblages of neglected infectious agents. We focus on a gradient of three widely-distributed cancers with an infectious cause: bladder (~2% of recorded cancer cases are due to Shistosoma haematobium), liv…

0301 basic medicineMicrobiology (medical)Endemic Diseases[SDV.CAN]Life Sciences [q-bio]/CancerMicrobiologyBiomesHelicobacter Infections[ SDV.CAN ] Life Sciences [q-bio]/Cancer03 medical and health sciencesSchistosomiasis haematobiaEnvironmental healthNeoplasmsPathogen-cancer interactionsEpidemiology of cancerGeneticsmedicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsHumansStomach cancerMolecular BiologyData miningEcology Evolution Behavior and SystematicsHuman cancer incidencesBladder cancerCancer preventionbiologyIncidenceCancerHelicobacter pyloriHepatitis Bmedicine.diseasebiology.organism_classificationHepatitis BHepatitis C3. Good health030104 developmental biologyInfectious DiseasesNeglected diseasesHost-Pathogen InteractionsFemalePublic HealthPublic health strategiesLiver cancer[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
researchProduct

Isolation and characterization of microsatellite markers in the liver fluke (Fasciola hepatica)

2004

PRIMER NOTE; International audience; Six microsatellite markers were isolated from Fasciola hepatica, a re-emerging parasite that causes important veterinary and public health problems. In a sample of 52 liver flukes from a region of hyperendemicity (Bolivian Altiplano), five microsatellite were polymorphic. Our results showed that liver flukes present important genetic variability, suggesting a preferential outcrossing reproduction mode for this hermaphroditic parasite.

microsatellitemedia_common.quotation_subjectOutcrossingBiochemistryGeneral Biochemistry Genetics and Molecular Biology030308 mycology & parasitology03 medical and health sciences[SDE.BE.PARA]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.paraparasitic diseasesParasite hostingFasciola hepaticaGenetic variability030304 developmental biologymedia_commonGenetics0303 health sciencesliver flukeEcologybiologyFasciola hepaticaLiver flukebiology.organism_classificationIsolation (microbiology)3. Good healthMicrosatelliteReproductionMolecular Ecology Notes
researchProduct