0000000000173973
AUTHOR
Juan Zhang
In-flight performance of the DAMPE silicon tracker
Abstract DAMPE (DArk Matter Particle Explorer) is a spaceborne high-energy cosmic ray and gamma-ray detector , successfully launched in December 2015. It is designed to probe astroparticle physics in the broad energy range from few GeV to 100 TeV. The scientific goals of DAMPE include the identification of possible signatures of Dark Matter annihilation or decay, the study of the origin and propagation mechanisms of cosmic-ray particles, and gamma-ray astronomy . DAMPE consists of four sub-detectors: a plastic scintillator strip detector, a Silicon–Tungsten tracKer–converter (STK), a BGO calorimeter and a neutron detector . The STK is composed of six double layers of single-sided silicon mi…
Internal alignment and position resolution of the silicon tracker of DAMPE determined with orbit data
Abstract The DArk Matter Particle Explorer (DAMPE) is a space-borne particle detector designed to probe electrons and gamma-rays in the few GeV to 10 TeV energy range, as well as cosmic-ray proton and nuclei components between 10 GeV and 100 TeV. The silicon–tungsten tracker–converter is a crucial component of DAMPE. It allows the direction of incoming photons converting into electron–positron pairs to be estimated, and the trajectory and charge (Z) of cosmic-ray particles to be identified. It consists of 768 silicon micro-strip sensors assembled in 6 double layers with a total active area of 6.6 m 2 . Silicon planes are interleaved with three layers of tungsten plates, resulting in about o…
Radiomic analysis reveals DCE-MRI features for prediction of molecular subtypes of breast cancer.
The purpose of this study was to investigate the role of features derived from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and to incorporated clinical information to predict the molecular subtypes of breast cancer. In particular, 60 breast cancers with the following four molecular subtypes were analyzed: luminal A, luminal B, human epidermal growth factor receptor-2 (HER2)-over-expressing and basal-like. The breast region was segmented and the suspicious tumor was depicted on sequentially scanned MR images from each case. In total, 90 features were obtained, including 88 imaging features related to morphology and texture as well as dynamic features from tumor and …
Transformation synthesis of aluminosilicate SSZ-39 zeolite from ZSM-5 and beta zeolite
Aluminosilicate SSZ-39 zeolite has been successfully prepared by transformation from ZSM-5 and beta zeolite in the presence of N,N-diethyl-cis-2,6-dimethylpiperidinium hydroxide (DMPOH) under hydrothermal conditions. Catalytic tests in the selective catalytic reduction of NOx with NH3 (NH3-SCR) show that the copper-exchanged products synthesized from the interzeolite transformation exhibit excellent catalytic performance.
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
Arrival of encephalitogenic T cells at inflammatory foci represents a critical step in development of experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. EBI2 and its ligand, 7{alpha},25-OHC, direct immune cell localization in secondary lymphoid organs. CH25H and CYP7B1 hydroxylate cholesterol to 7{alpha},25-OHC. During EAE, we found increased expression of CH25H by microglia and CYP7B1 by CNS-infiltrating immune cells elevating the ligand concentration in the CNS. Two critical pro-inflammatory cytokines, interleukin-23 (IL-23) and interleukin-1 beta (IL-1{beta}), maintained expression of EBI2 in differentiating Th17 cells. In line with this, EBI2 enhan…