0000000000177010

AUTHOR

M.l. Bondì

showing 8 related works from this author

Cationic SLN for siRNA and DNA plasmid delivery in hepatocellular carcinoma

2014

Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third leading cause of cancer-related deaths. For the treatment of HCC several drugs are under development, but the only one with proven survival benefit is sorafenib. This agent is a multikinase inhibitor that blocks Raf signaling and VEGF, PDGF and c-Kit. It has antiproliferative and antiangiogenic activity and delays tumor progression [1,2]. Moreover, systemic tumor-targeted gene delivery is attracting increasing attention as a promising alternative to conventional therapeutic strategies. At this purpose a large number of viral and non-viral vectors have been studied and applied as systems of stable transfec…

hepatocellular carcinoma DNA RNA cationic SLN
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PEGYLATED PHOSPHOLIPID-POLYASPARTAMIDE COPOLYMERS AS SELF-ASSEMBLING COLLOIDAL DRUG DELIVERY SYSTEMS

2009

Settore CHIM/09 - Farmaceutico Tecnologico Applicativophospholipids polyaspartamide drug delivery systems
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LIPID AND POLYMERIC NANOSTRUCTURES FOR BRAIN DRUG DELIVERY AND TARGETING

2009

Settore CHIM/09 - Farmaceutico Tecnologico Applicativolipid nanoparticles polymeric nanoparticles brain targeting
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LIPID NANOPARTICLES AS CARRIERS FOR TARGETED RELEASE OF RILUZOLE INTO THE CENTRAL NERVOUS SYSTEM

2009

Settore CHIM/09 - Farmaceutico Tecnologico Applicativosolid lipid nanoparticles central nervous system drug delivery
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PREPARATION AND CHARACTERIZATION OF CURCUMIN-LOADED LIPID NANOPARTICLES WITH IMPROVED ANTI-CANCER THERAPEUTIC EFFICACY

2011

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoSOLID LIPID NANOPARTICLES CURCUMIN COLLOIDAL DRUG CARRIERS
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NANOSTRUCTURED LIPID CARRIERS (NLC) AS DRUG DELIVERY SYSTEMS FOR SORAFENIB

2012

SORAFENIBSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoNLC
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ENCAPSULATION OF A MULTIKINASE INHIBITOR FOR THE TREATMENT OF HUMAN HEPATOCELLULAR CARCINOMA

2014

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoNANOSTRUCTURED LIPID CARRIER SORAFENIB
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Micelle polimeriche galattosilate contenenti Sorafenib: preparazione, caratterizzazione e studi di biodistribuzione

2013

Micelle sorafenib targetig attivo
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