0000000000179236

AUTHOR

Alfredo Pontillo

Using R via PHP for Teaching Purposes: R-php

This paper deals with the R-php statistical software, that is an environment for statistical analysis, freely accessible and attainable through the World Wide Web, based on R. Indeed, this software uses, as "engine" for statistical analyses, R via PHP and its design has been inspired by a paper of de Leeuw (1997). R-php is based on two modules: a base module and a point-and-click module. R-php base allows the simple editing of R code in a form. R-php point-and-click allows some statistical analyses by means of a graphical user interface (GUI): then, to use this module it is not necessary for the user to know the R environment, but all the allowed analyses can be performed by using the compu…

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A software tool via web for the statistical data analysis; R-php

The spread of Internet and the growing demand of services from the web users have changed and are still changing the way to organize the work or the study. Nowadays, the main part of information and many services are on the web and the software is going toward the same direction: in fact, the use of software implemented via web is ever-increasing, with a client-server logic that enables the “centralized” use of software installed on a server. In this paper we describe the Structure and the running of R-php, an environment for statistical analysis, freely accessible and attainable through the World Wide Web, based on the statistical environment R. R-php is based on two modules: a base module…

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A prospective, randomized study of empirical antifungal therapy for the treatment of chemotherapy-induced febrile neutropenia in children

Given that the rationale for empirical antifungal therapy in neutropenic children is limited and based on adult patient data, we performed a prospective, randomized, controlled trial that evaluated 110 neutropenic children with persistent fever. Those at high risk for invasive fungal infections (IFI) received caspofungin (Arm C) or liposomal amphotericinB (Arm B); those with a lower risk were randomized to receive Arm B, C, or no antifungal treatment (Arm A). Complete response to empirical antifungal therapy was achieved in 90/104 patients (86·5%): 48/56 at high risk (85·7%) [88·0% in Arm B; 83·9% in Arm C (P = 0·72)], and 42/48 at low risk (87·5%) [87·5% in control Arm A, 80·0% Arm B, 94·1…

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