0000000000179744

AUTHOR

S. Gomez

showing 2 related works from this author

Elucidating the catalytic reaction mechanism of orotate phosphoribosyltransferase by means of X-ray crystallography and computational simulations

2020

15 p.-8 fig.-2 tab.1 graph. abst.+ 8 fig. supl.-1 tab. supl.

PyrimidineStereochemistry010402 general chemistry01 natural sciencesCatalysisEnzyme catalysischemistry.chemical_compoundOrotidineNucleotideReaction mechanismchemistry.chemical_classificationMD simulations010405 organic chemistryHydrogen bondEnzyme catalysisGeneral ChemistryTautomer0104 chemical sciencesPyrimidine metabolismOrotate phosphoribosyltransferasechemistryPyrimidine metabolismOrotate phosphoribosyltransferaseQM/MM methodsX-ray structure
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Insights into the inhibited form of the redox-sensitive SufE-like sulfur acceptor CsdE

2017

17 p.-8 fig.

0301 basic medicineProtein ConformationDimerlcsh:MedicineMolecular DynamicsCrystallography X-RayPhysical ChemistryBiochemistryDEAD-box RNA HelicasesMolecular dynamicschemistry.chemical_compoundComputational ChemistryNucleophileBiochemical Simulationslcsh:ScienceMultidisciplinaryCrystallographyChemistryOrganic CompoundsPhysicsEscherichia coli ProteinsCondensed Matter Physics3. Good healthPhysical sciencesChemistryCarbon-Sulfur LyasesBiochemistryCrystal StructureResearch ArticleChemical ElementsProtein subunitChemical physicschemistry.chemical_elementOxidative phosphorylationMolecular Dynamics Simulation03 medical and health sciencesThiolsEscherichia coliSolid State PhysicsProtein Interaction Domains and MotifsChemical BondingOrganic Chemistrylcsh:RChemical CompoundsBiology and Life SciencesComputational BiologyDimers (Chemical physics)Hydrogen BondingCell BiologySulfurAcceptorRedox sensitiveOxidative Stress030104 developmental biologyBiophysicslcsh:QProtein MultimerizationSulfur
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