0000000000180158

AUTHOR

Elvira Lafuente

showing 3 related works from this author

Effects of anthropogenic stress on hosts and their microbiomes: Treated wastewater alters performance and gut microbiome of a key detritivore ( Asell…

2023

Human activity is a major driver of ecological and evolutionary change in wild populations and can have diverse effects on eukaryotic organisms as well as on environmental and host-associated microbial communities. Although host-microbiome interactions can be a major determinant of host fitness, few studies consider the joint responses of hosts and their microbiomes to anthropogenic changes. In freshwater ecosystems, wastewater is a widespread anthropogenic stressor that represents a multifarious environmental perturbation. Here, we experimentally tested the impact of treated wastewater on a keystone host (the freshwater isopod Asellus aquaticus) and its gut microbiome. We used a semi-natur…

freshwater ecosystemsisopodschemical pollutionisäntälajithost–microbiome interactionsenvironmental stressekosysteemit (ekologia)mikrobistohost-microbiome interactionssiiratsaastuminenGeneticsmakea vesiGeneral Agricultural and Biological Scienceschemical pollution; environmental stress; freshwater ecosystems; host-microbiome interactions; isopodsEcology Evolution Behavior and SystematicsEvolutionary Applications
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The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system

2014

The regulated head-to-tail expression of Hox genes provides a coordinate system for the activation of specific programmes of cell differentiation according to axial level. Recent work indicates that Hox expression can be regulated via RNA processing but the underlying mechanisms and biological significance of this form of regulation remain poorly understood. Here we explore these issues within the developing Drosophila central nervous system (CNS). We show that the pan-neural RNA-binding protein (RBP) ELAV (Hu antigen) regulates the RNA processing patterns of the Hox gene Ultrabithorax (Ubx) within the embryonic CNS. Using a combination of biochemical, genetic and imaging approaches we demo…

Embryo Nonmammaliananimal structuresNeurogenesisRNA-binding proteinCellular differentiationMolecular Sequence DataRNA-binding proteinBiologyAntennapediaNervous SystemMorphogenesisAnimalsDrosophila ProteinsRNA Processing Post-TranscriptionalELAV/HuHox geneMolecular BiologyTranscription factorPhylogenyResearch ArticlesUltrabithoraxHomeodomain ProteinsAlternative polyadenylation (APA)GeneticsBase SequenceAlternative splicingGenes HomeoboxGene Expression Regulation DevelopmentalSegment-specific apoptosisHoxCell biologyDrosophila melanogasterELAV ProteinsRNA processingCentral nervous systemembryonic structuresDrosophilaDrosophila ProteinTranscription FactorsAlternative splicingDevelopmental BiologyDevelopment
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Building on 150 Years of Knowledge : The Freshwater Isopod Asellus aquaticus as an Integrative Eco-Evolutionary Model System

2021

Interactions between organisms and their environments are central to how biological diversity arises and how natural populations and ecosystems respond to environmental change. These interactions involve processes by which phenotypes are affected by or respond to external conditions (e.g., via phenotypic plasticity or natural selection) as well as processes by which organisms reciprocally interact with the environment (e.g., via eco-evolutionary feedbacks). Organism-environment interactions can be highly dynamic and operate on different hierarchical levels, from genes and phenotypes to populations, communities, and ecosystems. Therefore, the study of organism-environment interactions requir…

freshwater ecosystemsAnimal model systems; ecosystem function; evolutionary ecology; freshwater ecosystems; integrative biology; organism-environment interactions; microbiomevesiekosysteemitmicrobiomeintegrative biologyAnimal model systemsorganism-environment interactionsevoluutioekologiamikrobistoevolutionary ecologysiiratecosystem functionmallit (mallintaminen)animal model systemvesiekologia
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