0000000000180861

AUTHOR

Jair Carneiro Leão

showing 4 related works from this author

HPV infection in relation to OSCC histological grading and TNM stage. Evalutation by traditional statistics and fuzzy logic model

2006

We aimed to evaluate if in oral squamous cell carcinoma (OSCC) there is a relationship between histological grading (HG), TNM clinical stage and HPV infection; and to study the performance of fuzzy logic compared to traditional statistics, in the analysis of HPV status and correlates of OSCC. In cross-sectional analysis, the study group comprised 63 patients (mean age 68.89 years (SD ± 11.78), range (32–93); males 28 (44.4%), females 35 (55.6%)) with OSCC histologically diagnosed. HPV-DNA was studied in exfoliated oral epithelial cells by nested PCR (MY09/MY11 and GP5+/GP6+ primers). Data were analysed in parallel by traditional statistics with multivariate analysis and a fuzzy logic (FL) t…

AdultMaleCancer ResearchMultivariate analysisStage iiBiologyModels BiologicalFuzzy LogicStatisticsCarcinomamedicineHumansGrading (tumors)AgedAged 80 and overOSCC HPV-DNA GradingPapillomavirus InfectionsHPV infectionMiddle Agedmedicine.diseasestomatognathic diseasesCross-Sectional StudiesIncreased riskOncologyMultivariate AnalysisCarcinoma Squamous CellFemaleMouth NeoplasmsPrimary tumour sizeOral SurgeryStage iv
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Quality assessment of systematic reviews regarding the effectiveness of zygomatic implants: an overview of systematic reviews

2020

Background Oral rehabilitation of atrophic maxillae features high complexity, for which there are several therapeutic modalities reported on scientific literature. Zygomatic implant placement is a viable option that features low morbidity and allows immediate prosthetic loading. The purpose of the present study was to determine the methodological quality of systematic reviews that assessed the effectiveness of zygomatic implants placed in atrophic maxillae. Material and Methods Searches were conducted on Medline via Pubmed, LILACS, Dare Cochrane, Scopus, and Sigle via Open Grey up to June 2019. Results Seven systematic reviews were eligible for Overview and comprised a total of 2313 patient…

medicine.medical_treatmentMEDLINEDentistryScientific literatureReview03 medical and health sciences0302 clinical medicinemedicineMucositisMaxillaHumansJaw EdentulousSinusitisGeneral DentistryDental ImplantsRehabilitationbusiness.industryDental prosthesisDental Implantation Endosseous030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Maxillary SinusitisSystematic reviewOtorhinolaryngologyMaxillaUNESCO::CIENCIAS MÉDICASSurgeryDental Prosthesis Implant-SupportedbusinessImplantologyFollow-Up StudiesSystematic Reviews as TopicMedicina Oral, Patología Oral y Cirugía Bucal
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Impact of xerostomia on the quality of life of patients submitted to head and neck radiotherapy

2019

Background The aim of the present work was to evaluate the impact of xerostomia on the quality of life of patients who underwent radiotherapy in the head and neck region. Material and Methods This was a cross-sectional, quantitative study. The sample comprised 40 patients whose xerostomia was classified through the xerostomia inventory and the quality of life evaluated through the oral health impact profile questionnaire (OHIP). Results The majority of participants were male (75%), mean age 58.7 years. According to the degree of severity of the xerostomia, the average score among the participants was 36 points, this being considered moderate xerostomia. A significant impact was observed, wi…

MalePhysical disabilityCross-sectional studymedicine.medical_treatmentDentistryOral healthXerostomia03 medical and health sciences0302 clinical medicineHead and neck radiotherapyQuality of lifestomatognathic systemSurveys and Questionnairesmedicineotorhinolaryngologic diseasesHumansHead and neckGeneral DentistryOral Medicine and Pathologybusiness.industryResearchMean age030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Radiation therapystomatognathic diseasesCross-Sectional StudiesOtorhinolaryngologyHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASQuality of LifeSurgerybusiness
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Evaluation of the salivary function of patients in treatment with radiotherapy for head and neck cancer submitted to photobiomodulation

2020

Background Head and neck radiotherapy is typically associated with toxicities that can have profound effects on the patient's quality of life. Xerostomia, which may or may not be related to hypofunction of the salivary gland, leading to negative consequences, mainly in quality of life, leaving patients more susceptible to the development of oral mucositis, dental caries, oral infection and difficulties in speech is one of the most common side effects of such treatment. The aim of the present study was to evaluate salivary function of patients in treatment with radiotherapy for head and neck cancer submitted to photobiomodulation. Material and Methods A cross-sectional study with a quantitat…

Maleretrospective studymedicine.medical_treatmentDentistryDental CariesXerostomiaSalivary functionQuality of lifeStatistical significancemedicineMucositisHumansclinical appearanceGeneral DentistryUNESCO:CIENCIAS MÉDICASOral Medicine and PathologytreatmentSalivary glandbusiness.industryResearchHead and neck cancergingival cancerCancerMiddle Agedmedicine.diseaseRadiation therapyCross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyHead and Neck NeoplasmsQuality of LifeFemaleSurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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