0000000000181136

AUTHOR

François Cauchy

showing 5 related works from this author

Enhancing capsule in hepatocellular carcinoma: intra-individual comparison between CT and MRI with extracellular contrast agent

2021

Purpose: The purpose of this study was to compare the value of contrast-enhanced computed tomography (CT) to that of magnetic resonance imaging obtained with extracellular contrast agent (ECA-MRI) for the diagnosis of a tumor capsule in hepatocellular carcinoma (HCC) using histopathologic findings as the standard of reference. Materials and methods: This retrospective study included patients with pathologically-proven resected HCCs with available preoperative contrast-enhanced CT and ECA-MRI examinations. Two blinded radiologists independently reviewed contrast-enhanced CT and ECA-MRI examinations to assess the presence of an enhancing capsule. The histopathological analysis of resected spe…

Gadolinium DTPAMaleCarcinoma HepatocellularContrast MediaComputed tomographySensitivity and SpecificityMcNemar's testExtracellularmedicineHumansRadiology Nuclear Medicine and imagingCapsule Computed tomography Extracellular contrast agent Hepatocellular carcinoma Magnetic resonance imagingAgedRetrospective StudiesRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryLiver NeoplasmsCapsuleMagnetic resonance imagingRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseMagnetic Resonance ImagingHepatocellular carcinomaFemaleTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessNuclear medicineKappaDiagnostic and Interventional Imaging
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Imaging-guided interventions modulating portal venous flow: Evidence and controversies

2021

Portal hypertension is defined by an increase in the portosystemic venous gradient. In most cases, increased resistance to portal blood flow is the initial cause of elevated portal pressure. More than 90% of cases of portal hypertension are estimated to be due to advanced chronic liver disease or cirrhosis. Transjugular intrahepatic portosystemic shunts, a non-pharmacological treatment for portal hypertension, involve the placement of a stent between the portal vein and the hepatic vein or inferior vena cava which helps bypass hepatic resistance. Portal hypertension may also be a result of extrahepatic portal vein thrombosis or compression. In these cases, percutaneous portal vein recanalis…

HepatologyGastroenterologyInternal MedicineImmunology and AllergyALPPS associating liver partition and portal vein ligation for staged hepatectomy transjugular intrahepatic portosystemic shunt BSG British Society of Gastroenterology EASL European Association for the Study of the Liver FLR future liver remnant HE hepatic encephalopathy NCBA N-butyl cyanoacrylate PH portal hypertension PVE portal vein embolisation PVR portal vein recanalisation TIPS transjugular intrahepatic portosystemic shunt Portal vein interventions TACE trans-arterial chemoembolization portal vein recanalization RCT randomised controlled trial portal vein embolization portal hypertension image guidedJHEP Reports
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Long-term Evolution of Hepatocellular Adenomas at MRI Follow-up.

2020

Background Hepatocellular adenomas (HCAs) are rare benign liver tumors. Guidelines recommend continued surveillance of patients diagnosed with HCAs, but these guidelines are mainly based on small studies or expert opinion. Purpose To analyze the long-term evolution of HCAs, including solitary and multiple lesions, and to identify predictive features of progression with MRI. Materials and Methods In a retrospective study, patients diagnosed with pathologically proven solitary or multiple HCAs between January 2004 and December 2015 were included; β-catenin-mutated HCAs and HCAs with foci of malignancy were considered to be at risk for progression. MRI examinations were analyzed, and tumor evo…

AdultMalePediatricsmedicine.medical_specialtyCarcinoma HepatocellularAdenomahepatocellular adenomaMEDLINEDiseaseliverMalignancyGastroenterology030218 nuclear medicine & medical imagingAdenoma Liver Cell03 medical and health sciencessymbols.namesakeText mining0302 clinical medicineMcNemar's testInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingFisher's exact testResponse Evaluation Criteria in Solid TumorsRetrospective Studiesbusiness.industryLiver NeoplasmsRetrospective cohort studymedicine.diseaseMagnetic Resonance ImagingTerm (time)Response Evaluation Criteria in Solid Tumors030220 oncology & carcinogenesissymbolsDisease ProgressionFemalebusinessProgressive diseaseMRIFollow-Up StudiesRadiology
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Differentiation of hepatocellular adenoma by subtype and hepatocellular carcinoma in non-cirrhotic liver by fractal analysis of perfusion MRI.

2022

Abstract Background To investigate whether fractal analysis of perfusion differentiates hepatocellular adenoma (HCA) subtypes and hepatocellular carcinoma (HCC) in non-cirrhotic liver by quantifying perfusion chaos using four-dimensional dynamic contrast-enhanced magnetic resonance imaging (4D-DCE-MRI). Results A retrospective population of 63 patients (47 female) with histopathologically characterized HCA and HCC in non-cirrhotic livers was investigated. Our population consisted of 13 hepatocyte nuclear factor (HNF)-1α-inactivated (H-HCAs), 7 β-catenin-exon-3-mutated (bex3-HCAs), 27 inflammatory HCAs (I-HCAs), and 16 HCCs. Four-dimensional fractal analysis was applied to arterial, portal v…

Fractals Perfusion Hepatocellular adenoma Hepatocellular carcinoma Magnetic resonance imagingRadiology Nuclear Medicine and imagingInsights into imaging
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Imaging features of histological subtypes of hepatocellular carcinoma: Implication for LI-RADS

2021

Background & Aims The histopathological subtypes of hepatocellular carcinoma (HCC) are associated with distinct clinical features and prognoses. This study aims to report Liver Imaging Reporting and Data System (LI-RADS)-defined imaging features of different HCC subtypes in a cohort of resected tumours and to assess the influence of HCC subtypes on computed tomography (CT)/magnetic resonance imaging (MRI) LI-RADS categorisation in the subgroup of high-risk patients. Methods This retrospective institutional review board-approved study included patients with resected HCCs and available histopathological classification. Three radiologists independently reviewed preoperative CT and MRI exams. T…

medicine.medical_specialtyHepatocellular carcinomaALT alanine transaminaseComputed tomographyRC799-869AST aspartate aminotransferaseOS overall survivalHistopathological subtypeMagnetic resonance imagingNOS-HCC not otherwise specified hepatocellular carcinomaInternal MedicinemedicineImmunology and AllergyIn patientComputed tomographyLI-RADS Liver Imaging Reporting and Data SystemLiver imagingHepatologymedicine.diagnostic_testbiologyUS ultrasoundbusiness.industryNot Otherwise SpecifiedGastroenterologyTIV tumour-in-veinMagnetic resonance imagingHBP hepatobiliary phaseDiseases of the digestive system. Gastroenterologymedicine.diseasedigestive system diseasesHistopathological subtypesCT computed tomographyRFS recurrence-free survivalAlanine transaminaseHepatocellular carcinomaSH-HCC steatohepatitic hepatocellular carcinomaCohortMTM-HCC macrotrabecular-massive hepatocellular carcinomabiology.proteinLI-RADSRadiologyAPHE arterial phase hyperenhancementbusinessHCC hepatocellular carcinomaMRI magnetic resonance imagingResearch ArticleJHEP Reports
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