0000000000181157

AUTHOR

Uwe Spelmeyer

showing 2 related works from this author

Acute exposure to 50ppm toluene does not increase sleepiness

2005

Abstract The Pupillographic Sleepiness Test (PST) is a new neurophysiological method to assess sleepiness. In an exposure study to a constant exposure level of 50 ppm toluene on 20 healthy men, our aim was to find out, if increased sleepiness could be seen with PST. PST was performed before and after 4.5 h of exposure. General complaints were assessed with the Swedish Performance Evaluation System (SPES) self-assessment questionnaire, once before and during exposure. Values obtained during exposure were related to pre-exposure values. Parametric cross-over analysis of logarithmic Pupillary Unrest Index (PUI) values did not show an effect of toluene exposure. In a nonparametric cross-over an…

PharmacologyEvaluation systembusiness.industryThreshold limit valueHealth Toxicology and MutagenesisGeneral MedicineToxicologymedicine.disease_causeExposure levelAnesthesiaAcute exposureTOLUENE EXPOSUREMedicineExposure chamberIrritationbusinessEnvironmental Toxicology and Pharmacology
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Acute effects of low doses of methyl parathion on human EEG.

2005

Abstract Biological monitoring of workers exposed to organophosphates consists mainly of measuring serum or erythrocyte cholinesterase activity. However, animal experiments and a field study suggest that quantitative analysis of EEG may be more sensitive. In a parallel group design, 25 farmers were investigated, spraying methyl parathion or water for 50 min. EEG was recorded before and after spraying. Serum and erythrocyte cholinesterase activity was compared with intraindividual pre-exposure values. Plasma methyl parathion concentrations ranged up to 12.1 μg/l, methyl paraoxon was not detectable. Based on plasma concentrations, two exposed subgroups were defined. In EEG recorded with close…

PharmacologyAcute effectsmedicine.medical_specialtyParaoxonbiologymedicine.diagnostic_testHealth Toxicology and MutagenesisLow doseGeneral MedicineElectroencephalographyToxicologychemistry.chemical_compoundEndocrinologychemistryAnesthesiaInternal medicineClosed eyesmedicineParathion methylbiology.proteinQuantitative analysis (chemistry)medicine.drugCholinesteraseEnvironmental toxicology and pharmacology
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