0000000000181187

AUTHOR

Inara Logina

showing 3 related works from this author

Association of human herpesvirus 6 and human herpesvirus 7 with demyelinating diseases of the nervous system.

2001

Peripheral blood mononuclear cells and plasma of 113 patients with neurological disorders and 150 blood donors were analyzed for HHV-6 and HHV-7 sequences by PCR. The prevalence of HHV-6 was significantly higher in patients with multiple sclerosis (P < 0.01) than in cases of nondemyelinating diseases of the central and demyelinating diseases of the peripheral nervous systems and blood donors. HHV-6 viremia was found only in patients with multiple sclerosis, predominantly in the active phase of the disease. A significantly higher frequency of HHV-7 reactivation in patients with demyelinating diseases of the peripheral nervous system suggests also its association with demyelinating processes.

Nervous systemAdultMalemedicine.medical_specialtyNeurologyMultiple SclerosisAdolescentvirusesHerpesvirus 6 HumanRoseolovirus InfectionsViremiaHerpesvirus 7 HumanDiseasePeripheral blood mononuclear cellPolymerase Chain ReactionCellular and Molecular NeuroscienceVirologyPrevalenceMedicineHumansViremiaAgedBrain Diseasesbiologybusiness.industryMultiple sclerosisvirus diseasesMiddle Agedmedicine.diseasebiology.organism_classificationmedicine.anatomical_structureNeurologyPeripheral nervous systemImmunologyDNA ViralHuman herpesvirus 6FemaleNeurology (clinical)businessJournal of neurovirology
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Correlation between HHV-6 reactivation and multiple sclerosis disease activity.

2002

This study examined the association between HHV-6 infection and multiple sclerosis (MS) and the relationship between HHV-6 reactivation and disease activity. The frequency of HHV-6 genomic sequences in peripheral blood mononuclear cells (PBMCs), the incidence of plasma viremia (nPCR), the transcription of viral mRNA in PBMCs (RT-PCR), the presence of antiviral IgM and IgG class antibodies in the plasma (IFA) of 16 relapsing/remitting and secondary progressive MS patients were studied in comparison with clinical manifestations of the disease, magnetic resonance imaging (MRI) of brain, and serum interleukin (IL)-12 concentrations (ELISA). The prevalence of HHV-6 infection was significantly hi…

ExacerbationvirusesHerpesvirus 6 HumanViremiaEnzyme-Linked Immunosorbent Assaymedicine.disease_causePeripheral blood mononuclear cellHerpesviridaeCentral nervous system diseaseMultiple Sclerosis Relapsing-RemittingVirologymedicineHumansCells Culturedbiologybusiness.industryReverse Transcriptase Polymerase Chain ReactionMultiple sclerosisvirus diseasesInterleukinHerpesviridae Infectionsmedicine.diseaseVirologyInfectious DiseasesImmunoglobulin MImmunoglobulin GImmunologybiology.proteinLeukocytes MononuclearVirus ActivationAntibodybusinessJournal of medical virology
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Imaging photoplethysmography for assessment of chronic pain patients

2019

In present pilot study application of multi-spectral imaging photoplethysmography for assessment of chronic pain patients during topical skin heating test was proposed. Photoplethysmography signal was recorded at 420nm, 530nm and 810nm illumination from the skin and corresponding perfusion indexes and perfusion maps were calculated. The novel parameter-PPGflare index was introduced and compared in neuropathic patients and healthy volunteers. Preliminary results suggest that neuropathic patients exhibited significantly lower PPGflare index, and that local heating substantially change PPG waveform at heat exposed skin region. Present study emphasizes advantages of imaging photoplethysmography…

medicine.medical_specialtybusiness.industryPain assessmentPhotoplethysmogramNeuropathic painHealthy volunteersChronic painMedicineRadiologyLaser Doppler velocimetrybusinessmedicine.diseasePerfusionOptical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics
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