0000000000185710

AUTHOR

R. Piepenburg

showing 3 related works from this author

Klinische Relevanz der Anti-CEA-Immunszintigraphie mit dem99mTc-markierten monoklonalen Antikörper BW 431/26

1992

The results of 119 radioimmunoscintigraphies (RIS) in 113 patients with the 99mTc-labeled monoclonal anti-CEA-antibody BW 431/26 (Behring) have been analysed. The aim of our study was the estimation of the method's sensitivity and specificity under different aspects to find out for which indications and questions the 99mTc-RIS is useful. Colorectal primary tumours in 19 patients were scintigraphically detected with a sensitivity of 83% and a specificity of 100%; 3 out of 7 other tumour sites were localised correctly. 55 patients were examined during the follow-up of colorectal cancer. There were 17 out of 22 true positive findings of local recurrences (sensitivity 77%, specificity 88%). Liv…

medicine.medical_specialtyPathologymedicine.drug_classColorectal cancerbusiness.industryAnti-CEA AntibodyCancerMonoclonal antibodymedicine.diseaseGastroenterologyImmunoscintigraphyInternal medicineMonoclonalmedicineRadiology Nuclear Medicine and imagingCritical assessmentClinical significancebusinessRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Bedeutung der Ganzkörper-Skelettszintigraphie im Rahmen des Staging von Malignomen im HNO-Bereich*

1992

Concerning malignant tumours of the oral cavity, pharynx and larynx, bone metastases are in general rarely seen. For the specification to which patients the whole body bone scintigraphy as detection method should be applied, the findings of 370 patients were analysed retrospectively. In respect of primary staging, bone metastases could be found by scintigraphy in only 1.4% of the patients. On the other hand, there was a detection rate of 12% during the further course of the disease, especially in case of clinical symptoms pointing at spreading metastases or in tumour recurrences. Nevertheless, positive scan findings which were not due to metastases could be found in both groups with equal f…

Larynxmedicine.diagnostic_testBone diseasebusiness.industryPharynxCancermedicine.diseaseScintigraphyMetastasisBone scanningmedicine.anatomical_structureOtorhinolaryngologyBone scintigraphymedicinebusinessNuclear medicineLaryngo-Rhino-Otologie
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99mTc–MAG3–Nierenfunktionsszintigraphie ohne und mit Captopril zur Diagnostik der renovaskulären Hypertonie

1993

In this study, the diagnostic value of renal function scintigraphy performed both without and with ACE inhibition has been evaluated using the new radiopharmaceutical 99mTc-MAG3. In cases of decompensated renal artery stenoses, the typical scan finding with this tubular excreted agent was shown to be a distinct parenchymal nuclide retention in combination with a delayed appearance of the radiotracer in the pelvic system. Using this criterion in 43 patients with suspected renovascular hypertension, sensitivity and specificity were 89 and 88%, respectively. Bilateral positive findings were non-specific; excluding them from the study, specificity increased to 100%. In renal insufficiency, capt…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryUrologyRenal functionCaptoprilurologic and male genital diseasesScintigraphymedicine.diseaseRenal artery stenosisSurgeryRenovascular hypertensionStenosismedicine.arterymedicineRadiology Nuclear Medicine and imagingRenal arterybusinessTechnetium-99mmedicine.drugRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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