Artificial intelligence techniques for cancer treatment planning
An artificial intelligence system, NEWCHEM, for the development of new oncology therapies is described. This system takes into account the most recent advances in molecular and cellular biology and in cell-drug interaction, and aims to guide experimentation in the design of new optimal protocols. Further work is being carried out, aimed to embody in the system all the basic knowledge of biology, physiopathology and pharmacology, to reason qualitatively from first principles so as to be able to suggest cancer therapies.
Visual knowledge processing in computer-assisted radiology: A consultation system
This paper presents Visual Heuristics, a consultation system for diagnosis based on thorax radiograph recording. Visual Heuristics uses both prototypical representations of physiological and pathological states and reasoning aimed to infer conclusions from pathological or physiological conditions, establishing correspondences between pathological or physiological states and semantic descriptions of images. Images are assembled with groups of descriptors that guide the recognition process, achieving the possibility of comparisons with real images on the basis of 'expected' images. The system may be employed to generate a dynamic atlas that does not contain proper images, but generates them.
QUALITATIVE MODELING OF CELL GROWTH PROCESSES
In this paper we present a qualitative physics model to reason about cell growth processes and cell-drug interactions, to be used in the knowledge base of NEWCHEM, an expert system intended to guide experimentation in the design of new optimal protocols in cancer treatment, After a brief discussion of the contributions that artificial intelligence techniques could make in cancer research and a brief presentation of some currently developed expert systems, some details of the proposed model based on the Forbus and Kuipers approaches to qualitative physics are given and its implementation as a LISP program is briefly discussed.
A qualitative model of the HIV vital cycle
Qualitative modelling is a recent artificial intelligence approach to physical system modelling. This approach has been successfully applied in several fields. On the basis of an analysis and qualitative modelling of cell growth, we reckon that a qualitative model of the vital cycle of HIV can be proposed, including the phases in which HIV can be attacked. The actions of antiviral drugs can also be qualitatively modelled, provided their action mechanism is known, even only in a broad sense.