0000000000186083
AUTHOR
Claudio Nicolini
Artificial intelligence techniques for cancer treatment planning
An artificial intelligence system, NEWCHEM, for the development of new oncology therapies is described. This system takes into account the most recent advances in molecular and cellular biology and in cell-drug interaction, and aims to guide experimentation in the design of new optimal protocols. Further work is being carried out, aimed to embody in the system all the basic knowledge of biology, physiopathology and pharmacology, to reason qualitatively from first principles so as to be able to suggest cancer therapies.
QUALITATIVE MODELING OF CELL GROWTH PROCESSES
In this paper we present a qualitative physics model to reason about cell growth processes and cell-drug interactions, to be used in the knowledge base of NEWCHEM, an expert system intended to guide experimentation in the design of new optimal protocols in cancer treatment, After a brief discussion of the contributions that artificial intelligence techniques could make in cancer research and a brief presentation of some currently developed expert systems, some details of the proposed model based on the Forbus and Kuipers approaches to qualitative physics are given and its implementation as a LISP program is briefly discussed.